• Iberian red deer: paraphyletic nature at mtDNA but nuclear markers support its genetic identity 

      Carranza, Juan; Salinas, María; Andrés Cara, Damián de Upna; Pérez González, Javier (Wiley, 2016)   Artículo / Artikulua  OpenAccess
      Red deer populations in the Iberian glacial refugium were the main source for postglacial recolonization and subspecific radiation in north-western Europe. However, the phylogenetic history of Iberian red deer (Cervus ...
    • Identification of lptA, lpxE, and lpxO, three genes involved in the remodeling of Brucella cell envelope 

      Conde Álvarez, Raquel; Palacios Chaves, Leyre; Gil Ramírez, Yolanda Upna; Salvador Bescós, Miriam; Bárcena Varela, Marina; Aragón Aranda, Beatriz; Martínez Gómez, Estrella; Zúñiga Ripa, Amaia; Miguel López, María Jesús de; Bartholomew, Toby Leigh; Hanniffy, Sean; Grilló Dolset, María Jesús; Vences Guzmán, Miguel Ángel; Bengoechea Alonso, José Antonio; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moriyón Uría, Ignacio; Iriarte, Maite (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      The brucellae are facultative intracellular bacteria that cause a worldwide extended zoonosis. One of the pathogenicity mechanisms of these bacteria is their ability to avoid rapid recognition by innate immunity because ...
    • Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection 

      Crespo, Helena Upna; Reina Arias, Ramsés Upna; Glaría Ezquer, Idoia Upna; Ramírez, Hugo Upna; Andrés, Ximena de; Jauregui, Paula; Luján, Lluís; Martínez Pomares, Luisa; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna (BioMed Central, 2011)   Artículo / Artikulua  OpenAccess
      This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ...
    • Iflavirus increases its infectivity and physical stability in association with baculovirus 

      Jakubowska, Agata K.; Murillo Pérez, Rosa Upna; Carballo Palos, Arkaitz; Williams, Trevor Upna; Lent, Jan W. M. van; Caballero Murillo, Primitivo Upna; Herrero, Salvador (PeerJ, 2016)   Artículo / Artikulua  OpenAccess
      Virus transmission and the prevalence of infection depend on multiple factors, including the interaction with other viral pathogens infecting the same host. In this study, active replication of an iflavirus, Spodoptera ...
    • Immunization against small ruminant lentiviruses 

      Reina Arias, Ramsés Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna (MDPI, 2013)   Artículo / Artikulua  OpenAccess
      Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered ...
    • In vivo monitoring of Staphylococcus aureus biofilm infections and antimicrobial therapy by [18F]fluoro-deoxyglucose–MicroPET in a mouse model 

      Garrido, Victoria Upna; Collantes, María; Barberán, Montserrat; Peñuelas, Iván; Arbizu, Javier; Amorena Zabalza, Beatriz Upna; Grilló Dolset, María Jesús (American Society for Microbiology, 2014)   Artículo / Artikulua  OpenAccess
      A mouse model was developed for in vivo monitoring of infection and the effect of antimicrobial treatment against Staphylococcus aureus biofilms, using the [18F]fluoro-deoxyglucose–MicroPET ([18F]FDG-MicroPET) image ...
    • Inactivation of the Thymidylate synthase thyA in non-typeable Haemophilus influenzae modulates antibiotic resistance and has a strong impact on its interplay with the host airways 

      Rodríguez Arce, Irene; Martí, Sara; Euba, Begoña; Fernández Calvet, Ariadna; Moleres Apilluelo, Javier; López López, Nahikari; Barberán, Montserrat; Ramos Vivas, José; Tubau, Fe; Losa, Carmen; Ardanuy, Carmen; Leiva, José; Yuste, José E.; Garmendia García, Juncal (Frontiers Media, 2017)   Artículo / Artikulua  OpenAccess
      Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate ...
    • Increased bioethanol production from commercial tobacco cultivars overexpressing thioredoxin f grown under field conditions 

      Farrán Blanch, Inmaculada Upna; Fernández San Millán, Alicia Upna; Ancín Rípodas, María Upna; Larraya Reta, Luis María Upna; Veramendi Charola, Jon Upna (Springer, 2014)   Artículo / Artikulua  OpenAccess
      Bioethanol is mainly produced from food crops such as sugar cane and maize while it has been held partly responsible for the rise of food commodity prices. Tobacco, integrated in biorefinery facilities for the extraction ...
    • Increased biofilm formation by nontypeable Haemophilus influenzae isolates from patients with invasive disease or otitis media versus strains recovered from cases of respiratory infections 

      Puig, Carmen Upna; Domenech, Arnau; Garmendia García, Juncal; Langereis, Jeroen D.; Mayer, Pascal; Calatayud, Laura; Liñares, Josefina; Ardanuy, Carmen; Martí, Sara (American Society for Microbiology, 2014)   Artículo / Artikulua  OpenAccess
      Biofilm formation by nontypeable (NT) Haemophilus influenzae remains a controversial topic. Nevertheless, biofilm-like structures have been observed in the middle-ear mucosa of experimental chinchilla models of otitis media ...
    • Intra- and intergenerational persistence of an insect nucleopolyhedrovirus: adverse effects of sublethal disease on host development, reproduction, and susceptibility to superinfection 

      Cabodevilla de Andrés, Oihana; Villar, Eduardo; Virto Garayoa, Cristina Upna; Murillo Pérez, Rosa Upna; Williams, Trevor Upna; Caballero Murillo, Primitivo Upna (American Society for Microbiology, 2011)   Artículo / Artikulua  OpenAccess
      Sublethal infections by Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) are common in field populations of the beet armyworm (S. exigua, Hübner) in the Almerian horticultural region of Spain. Inoculation of ...
    • Isotopic composition of maize as related to N-fertilization and irrigation in the Mediterranean region 

      Lasa Larrea, Berta; Irañeta, Iosu; Muro Erreguerena, Julio Upna; Irigoyen Iriarte, Ignacio Upna; Aparicio Tejo, Pedro María Upna (Escola Superior de Agricultura "Luiz de Queiroz", Universidade de São Paulo, 2011)   Artículo / Artikulua  OpenAccess
      Nitrate leaching as a result of excessive application of N-fertilizers and water use is a major problem of vulnerable regions. The farming of maize requires high N fertilization and water inputs in Spain. Isotopic ...
    • Killing niche competitors by remote-control bacteriophage induction 

      Selva, Laura; Viana, David; Regev Yochay, Gili; Trzcinski, Krzysztof; Corpa, Juan Manuel; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Penadés, José R. (National Academy of Sciences, 2009)   Artículo / Artikulua  OpenAccess
      A surprising example of interspecies competition is the production by certain bacteria of hydrogen peroxide at concentrations that are lethal for others. A case in point is the displacement of Staphylococcus aureus by ...
    • Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells 

      March, Catalina; Moranta, David; Regueiro, Verónica; Llobet, Enrique; Tomás, Anna; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (American Society for Biochemistry and Molecular Biology, 2011)   Artículo / Artikulua  OpenAccess
      Outer membrane protein A (OmpA) is a class of proteins highly conserved among the Enterobacteriaceae family and throughout evolution. Klebsiella pneumoniae is a capsulated Gram-negative pathogen. It is an important cause ...
    • Lacanobia oleracea nucleopolyhedrovirus (LaolNPV): a new European species of alphabaculovirus with a narrow host range 

      Simón de Goñi, Oihane; Erlandson, Martin A.; Frayssinet, Marie; Williams, Trevor Upna; Theilmann, David A.; Volkoff, Anne Nathalie; Caballero Murillo, Primitivo Upna (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      During an insect sampling program in alfalfa crops near Montpellier, France in 2011, Lacanobia oleracea larvae were collected that died due to nucleopolyhedrovirus infection (LaolNPV). This virus was subjected to molecular ...
    • Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers 

      Salazar, Eider; Berriatua, Eduardo; Pérez, Marta; Marín, Belén; Acin, Cristina; Martín Burriel, Inmaculada; Reina Arias, Ramsés Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)   Artículo / Artikulua  OpenAccess
      The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and ...
    • Lack of the PGA exopolysaccharide in Salmonella as an adaptive trait for survival in the host 

      Echeverz Sarasúa, Maite Upna; García Martínez, Begoña Upna; Sabalza Baztán, Amaia; Valle Turrillas, Jaione Upna; Gabaldón Estevan, Juan Antonio; Solano Goñi, Cristina Upna; Lasa Uzcudun, Íñigo Upna (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      Many bacteria build biofilm matrices using a conserved exopolysaccharide named PGA or PNAG (poly-β-1,6-N-acetyl-D-glucosamine). Interestingly, while E. coli and other members of the family Enterobacteriaceae encode the ...
    • Leaf δ15N as a physiological indicator of the responsiveness of N2-fixing alfalfa plants to elevated CO2, temperature and low water availability 

      Ariz, Idoia Upna; Cruz, Cristina; Neves, Tomé; Irigoyen, J. Juan; García Olaverri, Carmen Upna; Nogués, Salvador; Aparicio Tejo, Pedro María Upna; Aranjuelo Michelena, Iker (Frontiers Media, 2015)   Artículo / Artikulua  OpenAccess
      The natural 15N/14N isotope composition (δ15N) of a tissue is a consequence of its N source and N physiological mechanisms in response to the environment. It could potentially be used as a tracer of N metabolism in plants ...
    • Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit 

      Crespo, Helena Upna; Guillén, Hugo; Pablo Maiso, Lorena de; Gómez Arrebola, Carmen; Rodríguez, Gregorio; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna; Reina Arias, Ramsés Upna (Taylor & Francis, 2017)   Artículo / Artikulua  OpenAccess
      β-glucans exhibited in cell walls of several pathogens as bacteria or fungi are sensed by pathogen recognition receptors such as scavenger receptors present in antigen presenting cells, i.e., macrophages. β-glucans obtained ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Conde Álvarez, Raquel; Bargen, Kristine von; Grilló Dolset, María Jesús; Jerala, Roman; Brandenburg, Klaus; Llobet, Enrique; Bengoechea Alonso, José Antonio; Moreno, Edgardo; Moriyón Uría, Ignacio; Gorvel, Jean-Pierre; Arce Gorvel, Vilma; Iriarte, Maite; Mancek Keber, Mateja; Barquero Calvo, Elías; Palacios Chaves, Leyre; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Martirosyan, Anna (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
    • Maedi-visna virus infection of ovine mammary epithelial cells 

      Bolea, Rosa; Monleón, Eva; Carrasco, Librado; Vargas, Antonia; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (EDP Sciences, 2006)   Artículo / Artikulua  OpenAccess
      The aim of this work was to perform a complete study of maedi-visna virus (MVV) infected mammary glands of naturally-infected sheep, and to determine if cells other than macrophages undergo a productive viral infection in ...