• Plastidic phosphoglucose isomerase is an important determinant of starch accumulation in mesophyll cells, growth, photosynthetic capacity, and biosynthesis of plastidic cytokinins in Arabidopsis 

      Bahaji, Abdellatif; Sánchez López, Ángela María; Diego, Nuria de; Muñoz Pérez, Francisco José; Baroja Fernández, Edurne Upna; Li, Jun; Ricarte Bermejo, Adriana; Baslam, Marouane; Aranjuelo Michelena, Iker; Almagro Zabalza, Goizeder Upna; Humplik, Jan F.; Novák, Ondrej; Spíchal, Lukás; Dolezal, Karel; Pozueta Romero, Javier Upna (Public Library of Science, 2015)   Artículo / Artikulua  OpenAccess
      Phosphoglucose isomerase (PGI) catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. It is involved in glycolysis and in the regeneration of glucose-6-P molecules in the oxidative pentose ...
    • Post-entry blockade of small ruminant lentiviruses by wild ruminants 

      Sanjosé, Leticia; Crespo, Helena Upna; Blatti-Cardinaux, Laure; Glaría Ezquer, Idoia Upna; Martínez Carrasco, Carlos; Berriatua, Eduardo; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna; Bertoni, Giuseppe; Reina Arias, Ramsés Upna (BioMed Central, 2016)   Artículo / Artikulua  OpenAccess
      Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...
    • Post-harvest light treatment increases expression levels of recombinant proteins in transformed plastids of potato tubers 

      Larraya Reta, Luis María Upna; Fernández San Millán, Alicia Upna; Ancín Rípodas, María Upna; Farrán Blanch, Inmaculada Upna; Veramendi Charola, Jon Upna (Wiley, 2015)   Artículo / Artikulua  OpenAccess
      Plastid genetic engineering represents an attractive system for the production of foreign proteins in plants. Although high expression levels can be achieved in leaf chloroplasts, the results for non-photosynthetic plastids ...
    • Protein A-mediated multicellular behavior in Staphylococcus aureus 

      Merino, Nekane; Toledo Arana, Alejandro Upna; Vergara Irigaray, Marta Upna; Valle Turrillas, Jaione Upna; Solano Goñi, Cristina Upna; Calvo, Enrique; Lopez, Juan Antonio; Foster, Timothy J.; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
      The capacity of Staphylococcus aureus to form biofilms on host tissues and implanted medical devices is one of the major virulence traits underlying persistent and chronic infections. The matrix in which S. aureus cells ...
    • The regulon of the RNA chaperone CspA and its auto-regulation in Staphylococcus aureus 

      Caballero Sánchez, Carlos; Menéndez Gil, Pilar; Catalán Moreno, Arancha; Vergara Irigaray, Marta Upna; García Martínez, Begoña Upna; Segura, Víctor; Irurzun Domínguez, Naiara; Villanueva San Martín, Maite Upna; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna; Lasa Uzcudun, Íñigo Upna; Toledo Arana, Alejandro Upna (Oxford University Press, 2018)   Artículo / Artikulua  OpenAccess
      RNA-binding proteins (RBPs) are essential to finetune gene expression. RBPs containing the coldshock domain are RNA chaperones that have been extensively studied. However, the RNA targets and specific functions for ...
    • Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection 

      Euba, Begoña; Moleres Apilluelo, Javier; Viadas Martínez, Cristina Upna; Barberán, Montserrat; Caballero Coronado, Lucía; Grilló Dolset, María Jesús; Bengoechea Alonso, José Antonio; Torres, Juan de; Liñares, Josefina; Leiva, José; Garmendia García, Juncal (American Society for Microbiology, 2015)   Artículo / Artikulua  OpenAccess
      Nontypeable Haemophilus influenzae (NTHI) is an opportunistic pathogen that is an important cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). COPD is an inflammatory disease of the airways, ...
    • Relative contribution of P5 and hap surface proteins to nontypable haemophilus influenzae interplay with the host upper and lower airways 

      Euba, Begoña; Moleres Apilluelo, Javier; Viadas Martínez, Cristina Upna; Ruiz de los Mozos Aliaga, Igor Upna; Valle Turrillas, Jaione Upna; Bengoechea Alonso, José Antonio; Garmendia, Junkal (Public Library of Science, 2015)   Artículo / Artikulua  OpenAccess
      Nontypable Haemophilus influenzae (NTHi) is a major cause of opportunistic respiratory tract disease, and initiates infection by colonizing the nasopharynx. Bacterial surface proteins play determining roles in the ...
    • Relative contributions of lipooligosaccharide inner and outer core modifications to nontypeable Haemophilus influenzae pathogenesis 

      Morey, Pau; Viadas Martínez, Cristina Upna; Euba, Begoña; Hood, Derek W.; Barberán, Montserrat; Gil Puig, Carmen Upna; Grilló Dolset, María Jesús; Bengoechea, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2013)   Artículo / Artikulua  OpenAccess
      Nontypeable Haemophilus influenzae (NTHi) is a frequent commensal of the human nasopharynx that causes opportunistic infection in immunocompromised individuals. Existing evidence associates lipooligosaccharide (LOS) with ...
    • Relevant role of fibronectin-binding proteins in Staphylococcus aureus biofilm-associated foreign-body infections 

      Vergara Irigaray, Marta Upna; Valle Turrillas, Jaione Upna; Merino, Nekane; Latasa Osta, Cristina Upna; García Martínez, Begoña Upna; Ruiz de los Mozos Aliaga, Igor; Solano Goñi, Cristina Upna; Toledo Arana, Alejandro Upna; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2009)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains ...
    • Resveratrol therapeutics combines both antimicrobial and immunomodulatory properties against respiratory infection by nontypeable Haemophilus influenzae 

      Euba, Begoña; López López, Nahikari; Rodríguez Arce, Irene; Fernández Calvet, Ariadna; Barberán, Montserrat; Caturla, Nuria; Martí, Sara; Díez Martínez, Roberto; Garmendia, Junkal (Springer Nature, 2017)   Artículo / Artikulua  OpenAccess
      The respiratory pathogen nontypeable Haemophilus influenzae (NTHi) is an important cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) that requires efficient treatments. A previous screening ...
    • RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria 

      Ferrer, María Desamparados; Quiles Puchalt, Nuria; Harwich, Michael D.; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Barbé, Jordi; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2011)   Artículo / Artikulua  OpenAccess
      Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
    • Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes 

      March, Catalina; Cano, Victoria; Moranta, David; Llobet, Enrique; Pérez Gutiérrez, Camino; Tomás, Juan M.; Suárez, Teresa; Garmendia, Junkal; Bengoechea Alonso, José Antonio (Public Library of Science, 2013)   Artículo / Artikulua  OpenAccess
      Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule ...
    • Role of biofilm-associated protein bap in the pathogenesis of bovine Staphylococcus aureus 

      Cucarella, Carme; Tormo, M. Ángeles; Ubeda, Carles; Trotonda, M. Pilar; Monzon, Marta; Peris, Cristòfol; Amorena Zabalza, Beatriz Upna; Lasa Uzcudun, Íñigo Upna; Penadés, José R. (American Society for Microbiology, 2004)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus is a common cause of intramammary infections, which frequently become chronic, associated with the ability of the bacteria to produce biofilm. Here, we report a relationship between the ability to ...
    • Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer 

      Maiques, Elisa; Ubeda, Carles; Tormo, María Ángeles; Ferrer, María Desamparados; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Penadés, José R. (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
      SaPIbov2 is a member of the SaPI family of staphylococcal pathogenicity islands and is very closely related to SaPIbov1. Typically, certain temperate phages can induce excision and replication of one or more of these islands ...
    • Role of the Omp25/Omp31 family in outer membrane properties and virulence of Brucella ovis 

      Caro-Hernandez, Paola; Fernandez-Lago, Luis; Miguel, María Jesús de; Martin-Martin, Ana I.; Cloeckaert, Axel; Grilló Dolset, María Jesús; Vizcaino, Nieves (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
      The genes coding for the five outer membrane proteins (OMPs) of the Omp25/Omp31 family expected to be located in the outer membrane (OM) of rough virulent Brucella ovis PA were inactivated to evaluate their role in virulence ...
    • Routes of transmission and consequences of small ruminant lentiviruses (SRLVs) infection and eradication schemes 

      Peterhans, Ernst; Greenland, Tim; Badiola, Juan; Harkiss, Gordon; Bertoni, Giuseppe; Amorena Zabalza, Beatriz Upna; Eliaszewicz, Muriel; Juste, Ramón; Krassnig, Renate; Lafont, Jean Pierre (EDP Sciences, 2004)   Artículo / Artikulua  OpenAccess
      Small ruminant lentiviruses (SRLV = maedi-visna in sheep and caprine arthritis encephalitis in goats) are distributed throughout most countries of the world, particularly Europe. Laboratories from 16 European countries ...
    • Salmonella biofilm development depends on the phosphorylation status of RcsB 

      Latasa Osta, Cristina Upna; García Martínez, Begoña Upna; Echeverz Sarasúa, Maite Upna; Toledo Arana, Alejandro Upna; Valle Turrillas, Jaione Upna; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina Upna; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...
    • SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development 

      Tormo Más, María Ángeles; Martí, Miguel; Valle Turrillas, Jaione Upna; Manna, Adhar C.; Cheung, Ambrose L.; Lasa Uzcudun, Íñigo Upna; Penadés, José R. (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      Staphylococcus epidermidis biofilm formation is associated with the production of the polysaccharide intercellular adhesin (PIA)--poly-N-acetylglucosamine polysaccharide (PNAG) by the products of the icaADBC operon. ...
    • SarA positively controls Bap-dependent biofilm formation in Staphylococcus aureus 

      Trotonda, María Pilar; Manna, Adhar C.; Cheung, Ambrose L.; Lasa Uzcudun, Íñigo Upna; Penadés, José R. (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      The biofilm-associated protein Bap is a staphylococcal surface protein involved in biofilm formation. We investigated the influence of the global regulatory locus sarA on bap expression and Bap-dependent biofilm formation ...
    • Sensitivity of the ISO 6579:2002/Amd 1:2007 standard method for detection of Salmonella spp. on mesenteric lymph nodes from slaughter pigs 

      Mainar Jaime, Raúl Carlos; Andrés, S.; Vico, J. P.; San Román Aberasturi, Beatriz; Garrido, Victoria Upna; Grilló Dolset, María Jesús (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The ISO 6579:2002/Amd 1:2007 (ISO) standard has been the bacteriological standard method used in the European Union for the detection of Salmonella spp. in pig mesenteric lymph nodes (MLN), but there are no published ...