Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs
Fecha
2014Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión publicada / Argitaratu den bertsioa
Impacto
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10.1186/1746-6148-10-59
Resumen
Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered
one of the major sources of human infections in developed countries. Baseline studies on salmonellosis prevalence
in fattening pigs in Europe are based on direct pathogen isolation from mesenteric lymph nodes (MLN). This
procedure is considered the most reliable for diagnosing salmone ...
[++]
Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered
one of the major sources of human infections in developed countries. Baseline studies on salmonellosis prevalence
in fattening pigs in Europe are based on direct pathogen isolation from mesenteric lymph nodes (MLN). This
procedure is considered the most reliable for diagnosing salmonellosis in apparently healthy pigs. The presence of
simultaneous infections by different Salmonella strains in the same animal has never been reported and could have
important epidemiological implications.
Results: Fourteen finishing pigs belonging to 14 farms that showed high salmonellosis prevalence and a variety of
circulating Salmonella strains, were found infected by Salmonella spp, and 7 of them were simultaneously infected
with strains of 2 or 3 different serotypes. Typhimurium isolates showing resistance to several antimicrobials and
carrying mobile integrons were the most frequently identified in the colonized MLN. Four animals were found
infected by Salmonella spp. of a single serotype (Rissen or Derby) but showing 2 or 3 different antimicrobial
resistance profiles, without evidence of mobile genetic element exchange in vivo.
Conclusion: This is the first report clearly demonstrating that pigs naturally infected by Salmonella may harbour
different Salmonella strains simultaneously. This may have implications in the interpretation of results from baseline
studies, and also help to better understand human salmonellosis outbreaks and the horizontal transmission of
antimicrobial resistance genes. [--]
Materias
Salmonella,
Multiple infections,
Pigs,
Serotypes,
Antimicrobial resistance
Editor
BioMed Central
Publicado en
Veterinary Research, 2014, 10: 59
Departamento
Universidad Pública de Navarra/Nafarroako Unibertsitate Publikoa. IdAB. Instituto de Agrobiotecnología / Agrobioteknologiako Institutua
Versión del editor
Entidades Financiadoras
The work was financed by Gobierno de Navarra (project reference IIQ14064.RI1)
and INIA (project reference RTA2007-65). Contracts were funded by UPNA
(VG postdoctoral contract, and AZB predoctoral fellowship), EMUNDUS18
program (SS) and CSIC in collaboration with the European Social Fund
(BSR “Programa JAE-Doc” contract).
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La licencia del ítem se describe como © 2014 Garrido et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.