Relationship between handgrip strength and muscle mass in female survivors of breast cancer: a mediation analysis
Fecha
2017Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión publicada / Argitaratu den bertsioa
Impacto
|
10.3390/nu9070695
Resumen
This study explored the mediating factors of sarcopenia in a group of women survivors
of breast cancer in Bogotá, Colombia. This was a descriptive cross-sectional study with 98 women
survivors of breast cancer, who were registered with the SIMMON (Integrated Synergies to Improve
Oncological Management in Colombia) Foundation. Body weight, height, and waist circumference
(WC) were measured, an ...
[++]
This study explored the mediating factors of sarcopenia in a group of women survivors
of breast cancer in Bogotá, Colombia. This was a descriptive cross-sectional study with 98 women
survivors of breast cancer, who were registered with the SIMMON (Integrated Synergies to Improve
Oncological Management in Colombia) Foundation. Body weight, height, and waist circumference
(WC) were measured, and body mass index (BMI) was calculated. Body composition (percentage
of fat and muscle mass) was evaluated via four-pole bioelectrical impedance analysis. Sarcopenia
was defined as low muscle mass plus low grip strength or low gait speed (European Working Group
on Sarcopenia in Older People (EWGSOP) criteria). A “causal” mediation analysis with the Baron &
Kenny procedure (PROCESS® macro, Columbus, OH, USA) was used to explore variables related to
sarcopenia. Analyses were performed with the IBM SPSS 21 statistical package (SPSS Inc., Chicago, IL,
USA). The significance level of the results obtained in the hypothesis contrast was p < 0.05. The mean
age of the sample was 65.5 ± 5.9 years, with a BMI of 27.8 ± 4.7 kg/m2. The prevalence of sarcopenia
was 22.4%. Linear regression models suggest a partial mediation of anthropometric parameters (body
mass, body mass index and waist circumference) in the association between handgrip strength and
muscle mass. In conclusion, one in every five women survivors of breast cancer had sarcopenia.
The findings seem to emphasize the importance of obesity prevention in women survivors of breast
cancer, suggesting that high handgrip strength may not relate closely to greater muscle mass and
therefore would not exclude the risk of sarcopenia. [--]
Materias
Prevalence,
Body composition,
Sarcopenia,
Breast cancer,
Physical performance,
Adults
Editor
MDPI
Publicado en
Nutrients, 2017, 9, 695
Departamento
Universidad Pública de Navarra. Departamento de Ciencias de la Salud /
Nafarroako Unibertsitate Publikoa. Osasun Zientziak Saila
Versión del editor
Entidades Financiadoras
The authors thank the Centro de Estudios en Medición de la Actividad Física (CEMA) at
Universidad del Rosario for the financial and scientific support, respectively. Also, during the completion of this
paper, Antonio Garcia-Hermoso was visiting researchers at the University of Rosario (CEMA, Bogotá, Colombia),
supported with grants awarded by Proyectos Basales y Vicerrectoría de Investigación, Desarrollo e Innovación
(Universidad de Santiago de Chile, USACH).