Thermal degradation of type I collagen from bones
Fecha
2016Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión publicada / Argitaratu den bertsioa
Impacto
|
10.7569/JRM.2016.634111
Resumen
The denaturation processes of collagen in the temperature range between 450 K and 670 K are revealed through studies performed on cow rib bones by means of mechanical spectroscopy, differential scanning calorimetry, thermogravimetry, scanning electron microscopy and infrared spectroscopy. The conformational change of the collagen molecules from a triple helix structure to a random coil was found ...
[++]
The denaturation processes of collagen in the temperature range between 450 K and 670 K are revealed through studies performed on cow rib bones by means of mechanical spectroscopy, differential scanning calorimetry, thermogravimetry, scanning electron microscopy and infrared spectroscopy. The conformational change of the collagen molecules from a triple helix structure to a random coil was found at around 510 K. It was determined that the transformation is developed through the viscous movement of fibrils with an activation energy of (127 ± 8) kJ/mol. The second stage of massive bulk deterioration of the collagen was found at around 600 K, which leads to the loss of the mechanical integrity of the bulk collagen. In addition, an easy-to-handle viscoelastic procedure for obtaining the activation energy of the denaturation process from mechanical spectroscopy studies was also shown. [--]
Materias
Archaeometry,
Bone repair,
Thermal denaturation,
Tissue engineering,
Type I collagen
Editor
Tech Science Press
Publicado en
Journal of Renewable Materials, 2016, 4(4), 251-257
Departamento
Universidad Pública de Navarra. Departamento de Física /
Nafarroako Unibertsitate Publikoa. Fisika Saila /
Universidad Pública de Navarra/Nafarroako Unibertsitate Publikoa. Institute for Advanced Materials and Mathematics - INAMAT2
Versión del editor
Entidades Financiadoras
This work was partially supported by the CONICETPIP No. 179CO and 2098, the PID-UNR ING 450 and ING 453 (2014-2017) and the Collaboration Agreement between the Universidad Pública de Navarra and the
Universidad Nacional de Rosario, Res. 3247/2015.