• Association of blood-based DNA methylation markers with late-onset alzheimer disease: a potential diagnostic approach 

      Acha Santamaría, Blanca Upna Orcid; Corroza, Jon; Sánchez Ruiz de Gordoa, Javier Upna Orcid; Cabello, Carolina; Robles Solano, Maitane Upna; Méndez López, Iván Upna Orcid; Macías, Mónica; Zueco, Sara; Roldán, Miren Upna; Urdánoz Casado, Amaya Upna Orcid; Jericó Pascual, Ivonne Upna; Erro Aguirre, María Elena Upna; Alcolea, Daniel; Lleo, Alberto; Blanco Luquin, Idoia Upna; Mendióroz Iriarte, Maite Upna (Lippincott Williams & WilkinsAmerican Academy of Neurology, 2023)   Artículo / Artikulua  OpenAccess
      Background and Objectives: There is an urgent need to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent advances in blood-based measurements of phosphorylated tau (pTau) species are promising ...
    • Circular RNA expression profile in blood according to ischemic stroke etiology 

      Ostolaza, Aiora; Blanco Luquin, Idoia; Urdánoz Casado, Amaya Upna Orcid; Rubio, Idoya; Labarga, Alberto Upna Orcid (BioMed Central, 2020)   Artículo / Artikulua  OpenAccess
      Background: The discovery of novel biomarkers of stroke etiology would be most helpful in management of acute ischemic stroke patients. Recently, circular RNAs (circRNAs) have been proposed as candidate biomarkers of ...
    • Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients 

      Kular, Lara; Klose, Dennis; Urdánoz Casado, Amaya Upna Orcid; Ewing, Ewoud; Planell, Nuria; Gómez-Cabrero, David; Needhamsen, Maria; Jagodic, Maja (Frontiers Media, 2022)   Artículo / Artikulua  OpenAccess
      Background: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS) characterized by irreversible disability at later progressive stages. A growing body of ...
    • Gender-dependent deregulation of linear and circular RNA variants of homer1 in the entorhinal cortex of Alzheimer’s disease 

      Urdánoz Casado, Amaya Upna Orcid; Sánchez Ruiz de Gordoa, Javier Upna Orcid; Robles Solano, Maitane; Acha Santamaría, Blanca Upna Orcid; Roldán, Miren; Zelaya Huerta, María Victoria Upna Orcid; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      The HOMER1 gene is involved in synaptic plasticity, learning and memory. Recent studies show that circular RNA derived from HOMER1 (circHOMER1) expression is altered in some Alzheimer’s disease (AD) brain regions. In ...
    • Identificación de circRNAs como biomarcadores epigenéticos candidatos en la enfermedad de Alzheimer 

      Urdánoz Casado, Amaya Upna Orcid (2022)   Tesis doctoral / Doktoretza tesia
      La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa, crónica y, por el momento, irreversible que representa la primera causa de demencia relacionada con la edad. Su diagnóstico sigue siendo un reto. En los ...
    • NXN gene epigenetic changes in an adult neurogenesis model of Alzheimer's disease 

      Blanco Luquin, Idoia; Acha Santamaría, Blanca Upna Orcid; Urdánoz Casado, Amaya Upna Orcid; Gómez Orte, Eva; Roldán, Miren; Pérez Rodríguez, Diego R.; Cabello, Juan; Mendióroz Iriarte, Maite (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis in vitro model to recapitulate DNA methylation marks in the ...
    • Telomere length correlates with subtelomeric DNA methylation in long-term mindfulness practitioners 

      Mendióroz Iriarte, Maite; Puebla Guedea, Marta; Montero Marín, Jesús; Urdánoz Casado, Amaya Upna Orcid; Labarga, Alberto Upna Orcid (Nature Research, 2020)   Artículo / Artikulua  OpenAccess
      Mindfulness and meditation techniques have proven successful for the reduction of stress and improvement in general health. In addition, meditation is linked to longevity and longer telomere length, a proposed biomarker ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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