Now showing items 1-3 of 3

    • Gender-dependent deregulation of linear and circular RNA variants of homer1 in the entorhinal cortex of Alzheimer’s disease 

      Urdánoz Casado, Amaya Upna Orcid; Sánchez Ruiz de Gordoa, Javier Upna Orcid; Robles Solano, Maitane; Acha Santamaría, Blanca Upna Orcid; Roldán, Miren; Zelaya Huerta, María Victoria Upna Orcid; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      The HOMER1 gene is involved in synaptic plasticity, learning and memory. Recent studies show that circular RNA derived from HOMER1 (circHOMER1) expression is altered in some Alzheimer’s disease (AD) brain regions. In ...
    • Is the phenotype designation by PSP-MDS criteria stable throughout the disease course and consistent with tau distribution? 

      Sánchez Ruiz de Gordoa, Javier Upna Orcid; Zelaya Huerta, María Victoria Upna Orcid; Tellechea-Aramburo, Paula; Acha Santamaría, Blanca Upna Orcid; Roldán, Miren; Lopez Molina, Carlos; Coca, Valle; Galbete Jiménez, Arkaitz Upna Orcid; Mendioroz, Maite; Erro, M. Elena (Frontiers Media, 2022)   Artículo / Artikulua  OpenAccess
      Introduction: the MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do not discriminate the phenotype diversity. Our purpose was to search for anatomopathological differences among PSP phenotypes ...
    • NXN gene epigenetic changes in an adult neurogenesis model of Alzheimer's disease 

      Blanco Luquin, Idoia; Acha Santamaría, Blanca Upna Orcid; Urdánoz Casado, Amaya Upna Orcid; Gómez Orte, Eva; Roldán, Miren; Pérez Rodríguez, Diego R.; Cabello, Juan; Mendióroz Iriarte, Maite (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis in vitro model to recapitulate DNA methylation marks in the ...