Listar por autor UPNA "Andrés Cara, Damián de"

Mostrando ítems 1-20 de 24

    • Base genética del tropismo de lentivirus de pequeños rumiantes y estudio de la resistencia innata por APOBEC3 

      Glaría Ezquer, Idoia Upna (2015)   Tesis doctoral / Doktoretza tesia  OpenAccess
      Los lentivirus de pequeños rumiantes (SRLV), que incluyen al virus Visna/Maedi (VMV) y al de la artritis encefalitis caprina (CAEV), infectan ovejas y cabras distribuidas por todo el mundo causando un cuadro multisistémico ...

    • Characterization of ovine A3Z1 restriction properties against small ruminant lentiviruses (SRLVs) 

      Pablo Maiso, Lorena de Upna Orcid; Glaría Ezquer, Idoia Upna; Crespo, Helena Upna; Nistal Villán, Estanislao; Andrésdóttir, Valgerdur; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Reina Arias, Ramsés Upna Orcid (MDPI, 2017)   Artículo / Artikulua  OpenAccess
      Intrinsic factors of the innate immune system include the apolipoprotein B editing enzyme catalytic polypeptide-like 3 (APOBEC3) protein family. APOBEC3 inhibits replication of different virus families by cytosine ...

    • Detection of PrPSc in lung and mammary gland is favored by the presence of Visna/maedi virus lesions in naturally coinfected sheep 

      Salazar, Eider; Monleón, Eva; Bolea, Rosa; Acín, Cristina; Pérez, Marta María; Álvarez, Neila; Leginagoikoa, Iratxe; Juste, Ramón; Minguijón, Esmeralda; Reina Arias, Ramsés Upna Orcid; Glaría Ezquer, Idoia Upna; Berriatua, Eduardo; Andrés Cara, Damián de Upna Orcid; Badiola, Juan José; Amorena Zabalza, Beatriz Upna; Luján, Lluís (EDP Sciences, 2010)   Artículo / Artikulua  OpenAccess
      There are few reports on the pathogenesis of scrapie (Sc) and Visna/maedi virus (VMV) coinfections. The aim of this work was to study in vivo as well as post mortem both diseases in 91 sheep. Diagnosis of Sc and VMV ...

    • Diagnosing infection with small ruminant lentiviruses of genotypes A and B by combining synthetic peptides in ELISA 

      Sanjosé, Leticia; Crespo, Helena Upna; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna Orcid; Reina Arias, Ramsés Upna Orcid (Elsevier, 2015)   Artículo / Artikulua  OpenAccess
      The major challenges in diagnosing small ruminant lentivirus (SRLV) infection include early detection and genotyping of strains of epidemiological interest. A longitudinal study was carried out in Rasa Aragonesa sheep ...

    • Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq 

      Bilbao Arribas, Martin; Abendaño, Naiara; Varela Martínez, Endika; Reina Arias, Ramsés Upna Orcid; Andrés Cara, Damián de Upna Orcid; Jugo, Begoña M. (BioMed Central, 2019)   Artículo / Artikulua  OpenAccess
      Background: MicroRNAs (miRNAs) are short endogenous, single-stranded, noncoding small RNA molecules of approximately 22 nucleotides in length. They regulate gene expression posttranscriptionally by silencing mRNA expression, ...

    • Extensive rearing hinders Maedi-Visna Virus (MVV) infection in sheep 

      Leginagoikoa, Iratxe; Juste, Ramón; Barandika, Jesse; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna Orcid; Luján, Lluís; Badiola, Juan José; Berriatua, Eduardo (EDP Sciences, 2006)   Artículo / Artikulua  OpenAccess
      Maedi-Visna Virus (MVV) seroprevalence and its relationship with housing and mode of rearing of replacement ewe-lambs was investigated in 38 non-randomly selected sheep-flocks in Spain. They included extensive lamb-producing ...

    • The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice 

      San Román Aberasturi, Beatriz Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria Upna; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña Upna Orcid; Andrés, Ximena de; Zabaleta, Virginia Upna; Mansilla, Cristina; Farrán Blanch, Inmaculada Upna Orcid (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...

    • Growth performance and clinicopathological analyses in lambs repetitively inoculated with aluminum-hydroxide containing vaccines or aluminum-hydroxide only 

      Miguel, Ricardo de; Asín, Javier; Rodríguez Largo, Ana; Echeverría Garín, Irache Upna Orcid; Lacasta, Delia; Andrés Cara, Damián de Upna Orcid; Reina Arias, Ramsés Upna Orcid; Pinczowski, Pedro; Gimeno, Marina; Molín, Jéssica; Fernández, Antonio; Blas, Ignacio de; Pérez, Marta María; Luján, Lluís (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Aluminum (Al) hydroxide is an effective adjuvant used in sheep vaccines. However, Al-adjuvants have been implicated as potential contributors to a severe wasting syndrome in sheep— the so-called ovine autoimmune-inflammatory ...

    • Iberian red deer: paraphyletic nature at mtDNA but nuclear markers support its genetic identity 

      Carranza, Juan; Salinas, María; Andrés Cara, Damián de Upna Orcid; Pérez González, Javier (Wiley, 2016)   Artículo / Artikulua  OpenAccess
      Red deer populations in the Iberian glacial refugium were the main source for postglacial recolonization and subspecific radiation in north-western Europe. However, the phylogenetic history of Iberian red deer (Cervus ...

    • Identificación de lentivirus de pequeños rumiantes en granulomas post-vacunales y evaluación de métodos de diagnóstico y selección genética en la lucha frente a la infección 

      Echeverría Garín, Irache Upna Orcid (2021)   Tesis doctoral / Doktoretza tesia  OpenAccess
      Esta tesis plantea tres objetivos que se desarrollarán en tres capítulos independientes, correspondientes a sus respectivas publicaciones. Por un lado, se ha caracterizado la presencia y replicación de SRLV en macrófagos ...

    • Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection 

      Crespo, Helena Upna; Reina Arias, Ramsés Upna Orcid; Glaría Ezquer, Idoia Upna; Ramírez, Hugo Upna Orcid; Andrés, Ximena de; Jauregui, Paula; Luján, Lluís; Martínez Pomares, Luisa; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna Orcid (BioMed Central, 2011)   Artículo / Artikulua  OpenAccess
      This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ...

    • Immunization against small ruminant lentiviruses 

      Reina Arias, Ramsés Upna Orcid; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna (MDPI, 2013)   Artículo / Artikulua  OpenAccess
      Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered ...

    • Innate immunity against small ruminant lentiviruses (SRLV): characterization of APOBEC3-derived restriction 

      Pablo Maiso, Lorena de Upna Orcid (2020)   Tesis doctoral / Doktoretza tesia  OpenAccess
      En esta tesis se han llevado a cabo los siguientes estudios: 1. Identificación y caracterización de la restricción por APOBEC3 ovino frente a los SRLV. Se han estudiado dos tipos celulares que muestran restricción natural ...

    • Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers 

      Salazar, Eider; Berriatua, Eduardo; Pérez, Marta María; Marín, Belén; Acín, Cristina; Martín Burriel, Inmaculada; Reina Arias, Ramsés Upna Orcid; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)   Artículo / Artikulua  OpenAccess
      The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and ...

    • Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit 

      Crespo, Helena Upna; Guillén, Hugo; Pablo Maiso, Lorena de Upna Orcid; Gómez Arrebola, Carmen Upna Orcid; Rodríguez, Gregorio; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna Orcid; Reina Arias, Ramsés Upna Orcid (Taylor & Francis, 2017)   Artículo / Artikulua  OpenAccess
      β-glucans exhibited in cell walls of several pathogens as bacteria or fungi are sensed by pathogen recognition receptors such as scavenger receptors present in antigen presenting cells, i.e., macrophages. β-glucans obtained ...

    • Maedi-visna virus infection of ovine mammary epithelial cells 

      Bolea, Rosa; Monleón, Eva; Carrasco, Librado; Vargas, Antonia; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (EDP Sciences, 2006)   Artículo / Artikulua  OpenAccess
      The aim of this work was to perform a complete study of maedi-visna virus (MVV) infected mammary glands of naturally-infected sheep, and to determine if cells other than macrophages undergo a productive viral infection in ...

    • Mannose receptor may be involved in small ruminant lentivirus pathogenesis 

      Crespo, Helena Upna; Jauregui, Paula; Glaría Ezquer, Idoia Upna; Sanjosé, Leticia; Polledo, Laura; García Marín, Juan F.; Luján, Lluís; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Reina Arias, Ramsés Upna Orcid (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...

    • Molecular signature of aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing 

      Varela Martínez, Endika; Abendaño, Naiara; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta María; Reina Arias, Ramsés Upna Orcid; Andrés Cara, Damián de Upna Orcid; Luján, Lluís; Jugo, Begoña M. (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ...

    • Ovine TRIM5α can restrict visna/maedi virus 

      Jauregui, Paula; Crespo, Helena Upna; Glaría Ezquer, Idoia Upna; Luján, Lluís; Contreras, A.; Rosati, Sergio; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Towers, G. J.; Reina Arias, Ramsés Upna Orcid (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The restrictive properties of tripartite motif-containing 5 alpha (TRIM5α) from small ruminant species have not been explored. Here, we identify highly similar TRIM5α sequences in sheep and goats. Cells transduced with ...

    • Post-entry blockade of small ruminant lentiviruses by wild ruminants 

      Sanjosé, Leticia; Crespo, Helena Upna; Blatti-Cardinaux, Laure; Glaría Ezquer, Idoia Upna; Martínez Carrasco, Carlos; Berriatua, Eduardo; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna Orcid; Bertoni, Giuseppe; Reina Arias, Ramsés Upna Orcid (BioMed Central, 2016)   Artículo / Artikulua  OpenAccess
      Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...
      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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