• Anti-biofilm molecules targeting functional amyloids 

      Matilla Cuenca, Leticia Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Valle Turrillas, Jaione Upna Orcid (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      The choice of an effective therapeutic strategy in the treatment of biofilm-related infections is a significant issue. Amyloids, which have been historically related to human diseases, are now considered to be prevailing ...
    • Antibiofilm activity of flavonoids on staphylococcal biofilms through targeting BAP amyloids 

      Matilla Cuenca, Leticia Upna Orcid; Gil Puig, Carmen Upna Orcid; Cuesta Ferre, Sergio; Rapún Araiz, Beatriz Upna Orcid; Mira, Alex; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Ziemité, Miglé (Nature Research, 2020)   Artículo / Artikulua  OpenAccess
      The opportunistic pathogen Staphylococcus aureus is responsible for causing infections related to indwelling medical devices, where this pathogen is able to attach and form biofilms. The intrinsic properties given by the ...
    • Bacterial biofilm functionalization through Bap amyloid engineering 

      Matilla Cuenca, Leticia Upna Orcid; Taglialegna, Agustina Upna; Gil Puig, Carmen Upna Orcid; Toledo Arana, Alejandro; Lasa Uzcudun, Íñigo; Valle Turrillas, Jaione Upna Orcid (Springer Nature, 2022)   Artículo / Artikulua  OpenAccess
      Biofilm engineering has emerged as a controllable way to fabricate living structures with programmable functionalities. The amyloidogenic proteins comprising the biofilms can be engineered to create self-assembling ...
    • The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers 

      Taglialegna, Agustina Upna; Matilla Cuenca, Leticia Upna Orcid; Dorado Morales, Pedro Upna Orcid; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (Nature ResearchNanyang Technological University (Singapur), 2020)   Artículo / Artikulua  OpenAccess
      Functional amyloids are considered as common building block structures of the biofilm matrix in different bacteria. In previous work, we have shown that the staphylococcal surface protein Bap, a member of the Biofilm-Associated ...
    • lnsights into bacterial functional amyloids using the staphyiococcal Bap protein asan amyloid model 

      Matilla Cuenca, Leticia Upna Orcid (2022)   Tesis doctoral / Doktoretza tesia
      Los arniloides funcionales son componentes clave de la matriz del biofilrn de muchas bacterias. Estas estructuras proporcionan resistencia a las proteasas y a condiciones adversas de desnaturalización, y refuerzan y dan ...
    • Regulation of heterogenous lexA expression in staphylococcus aureus by an antisense RNA originating from transcriptional read-through upon natural mispairings in the sbrB intrinsic terminator 

      Bastet, Laurène; Bustos-Sanmamed, Pilar; Catalán Moreno, Arancha; Caballero Sánchez, Carlos Upna; Cuesta Ferre, Sergio; Matilla Cuenca, Leticia Upna Orcid; Villanueva San Martín, Maite Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Lasa Uzcudun, Íñigo; Toledo Arana, Alejandro (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Bacterial genomes are pervasively transcribed, generating a wide variety of antisense RNAs (asRNAs). Many of them originate from transcriptional read-through events (TREs) during the transcription termination process. ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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