• Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine 

      Mancilla, Marcos; Grilló Dolset, María Jesús; Miguel López, María Jesús de; López Goñi, Ignacio; San Román Aberasturi, Beatriz Upna Orcid; Zabalza Baranguá, Ana Upna; Moriyón Uría, Ignacio (BioMed Central, 2013)   Artículo / Artikulua  OpenAccess
      Brucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ...
    • Development of a selective culture medium for primary isolation of the main Brucella species 

      Miguel López, María Jesús de; Marín, Clara M.; Muñoz Álvaro, Pilar María; Dieste, L.; Grilló Dolset, María Jesús; Blasco, José María Upna (American Society for Microbiology, 2011)   Artículo / Artikulua  OpenAccess
      Bacteriological diagnosis of brucellosis is performed by culturing animal samples directly on both Farrell medium (FM) and modified Thayer-Martin medium (mTM). However, despite inhibiting most contaminating microorganisms, ...
    • Identification of lptA, lpxE, and lpxO, three genes involved in the remodeling of Brucella cell envelope 

      Conde Álvarez, Raquel; Palacios Chaves, Leyre; Gil Ramírez, Yolanda Upna; Salvador Bescós, Miriam; Bárcena-Varela, Marina; Aragón Aranda, Beatriz; Martínez Gómez, Estrella; Zúñiga Ripa, Amaia; Miguel López, María Jesús de; Bartholomew, Toby Leigh; Hanniffy, Sean; Grilló Dolset, María Jesús; Vences Guzmán, Miguel Ángel; Bengoechea Alonso, José Antonio; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moriyón Uría, Ignacio; Iriarte, Maite (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      The brucellae are facultative intracellular bacteria that cause a worldwide extended zoonosis. One of the pathogenicity mechanisms of these bacteria is their ability to avoid rapid recognition by innate immunity because ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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