Listar por autor "Ruberte, Ana Carolina"

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    • New formulation of a methylseleno-aspirin analog with anticancer activity towards colon cancer 

      Ruberte, Ana Carolina; González Gaitano, Gustavo; Sharma, Arun K.; Aydillo, Carlos; Encío Martínez, Ignacio Upna Orcid; Sanmartín, Carmen; Plano, Daniel (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Aspirin (ASA) has attracted wide interest of numerous scientists worldwide thanks to its chemopreventive and chemotherapeutic effects, particularly in colorectal cancer (CRC). Incorporation of selenium (Se) atom into ASA ...

    • Novel N,N′-disubstituted acylselenoureas as potential antioxidant and cytotoxic agents 

      Ruberte, Ana Carolina; Ramos Inza, Sandra; Aydillo, Carlos; Talavera, Irene; Encío Martínez, Ignacio Upna Orcid; Plano, Daniel; Sanmartín, Carmen (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Selenium compounds are pivotal in medicinal chemistry for their antitumoral and antioxidant properties. Forty seven acylselenoureas have been designed and synthesized following a fragment-based approach. Different scaffolds, ...

    • Novel selenadiazole derivatives as selective antitumor and radical scavenging agents 

      Ruberte, Ana Carolina; Plano, Daniel; Encío Martínez, Ignacio Upna Orcid; Aydillo, Carlos; Sharma, Arun K.; Sanmartín, Carmen (Elsevier, 2018)   Artículo / Artikulua  OpenAccess
      Twenty-seven novel benzo[c][1,2,5]selenadiazole-5-carboxylic acid (BSCA) derivatives were designed and synthesized. Anti-proliferative activity of these structures was tested in vitro against a panel of five human cancer ...
      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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