Listar por autor "Talavera, Irene"
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Novel N,N′-disubstituted acylselenoureas as potential antioxidant and cytotoxic agents
Ruberte, Ana Carolina; Ramos Inza, Sandra; Aydillo, Carlos; Talavera, Irene; Encío Martínez, Ignacio ; Plano, Daniel; Sanmartín, Carmen (MDPI, 2020) Artículo / ArtikuluaSelenium compounds are pivotal in medicinal chemistry for their antitumoral and antioxidant properties. Forty seven acylselenoureas have been designed and synthesized following a fragment-based approach. Different scaffolds, ... -
Seleno-analogs of scaffolds resembling natural products a novel warhead toward dual compounds
Astráin-Redín, Nora; Talavera, Irene; Moreno, Esther; Ramírez, María J.; Martínez-Sáez, Nuria; Encío Martínez, Ignacio ; Sharma, Arun K.; Sanmartín, Carmen; Plano, Daniel (MDPI, 2023) Artículo / ArtikuluaNowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated ...