• Novel N,N′-disubstituted acylselenoureas as potential antioxidant and cytotoxic agents 

      Ruberte, Ana Carolina; Ramos Inza, Sandra; Aydillo, Carlos; Talavera, Irene; Encío Martínez, Ignacio Upna Orcid; Plano, Daniel; Sanmartín, Carmen (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Selenium compounds are pivotal in medicinal chemistry for their antitumoral and antioxidant properties. Forty seven acylselenoureas have been designed and synthesized following a fragment-based approach. Different scaffolds, ...
    • Seleno-analogs of scaffolds resembling natural products a novel warhead toward dual compounds 

      Astráin-Redín, Nora; Talavera, Irene; Moreno, Esther; Ramírez, María J.; Martínez-Sáez, Nuria; Encío Martínez, Ignacio Upna Orcid; Sharma, Arun K.; Sanmartín, Carmen; Plano, Daniel (MDPI, 2023)   Artículo / Artikulua  OpenAccess
      Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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