Listar por tema "Aortic stenosis"
Mostrando ítems 1-7 de 7
-
Characterization of the sex-specific pattern of angiogenesis and lymphangiogenesis in aortic stenosis
Objective: We aim to analyze sex-related differences in angiogenesis and lymphangiogenesis in aortic valves (AVs) and valve interstitial cells (VICs) from aortic stenosis (AS) patients. Approach and Results: Totally 230 ... -
Diferencias específicas de sexo en angiogénesis y linfangiogénesis en la Estenosis Aórtica
(2022) Trabajo Fin de Máster/Master Amaierako LanaEste trabajo tuvo como objetivo estudiar el papel de la angiogénesis y linfangiogénesis en la estenosis aórtica (EA) y analizar las diferencias específicas de sexo de estos procesos a nivel histológico y molecular en ... -
Influence of diabetes mellitus on the pathological profile of aortic stenosis: a sex-based approach
Background: Diabetes mellitus (DM) accelerates the progression of aortic stenosis (AS), but how their underlying molecular mechanisms interact is not clear. Moreover, whether DM contributes to clinically relevant sex-differences ... -
Sex differences in aortic stenosis. A role for the aldosterone/mineralocorticoid receptor axis and its biotarget Galectin-3
(2023) Tesis doctoral / Doktoretza tesiaEn esta tesis doctoral, se ha empleado una cohorte de pacientes con EA severa sometidos a cirugía de reemplazo valvular. El tejido valvular recibido se ha dividido para realizar estudios a nivel histológico, a nivel ... -
Sex-dependent expression of neutrophil gelatinase-associated lipocalin in aortic stenosis
Background: Accumulating evidence suggest the existence of sex-related differences in the pathogenesis of aortic stenosis (AS) with inflammation, oxidative stress, fibrosis and calcification being over-represented in men. ... -
Sex-specific role of galectin-3 in aortic stenosis
Background: Aortic stenosis (AS) is characterized by infammation, fbrosis, osteogenesis and angiogenesis. Men and women develop these mechanisms diferently. Galectin-3 (Gal-3) is a pro-infammatory and pro-osteogenic lectin ... -
Targeting fatty acid-binding protein 4 improves pathologic features of aortic stenosis
Aortic stenosis (AS) is a fibrocalcific disease of the aortic valves (AVs). Sex-differences in AS pathophysiology have recently been described. High levels of fatty acid-binding protein 4 (FAPB4) in atherosclerotic plaques ...