Listar por tema "Mutants"
Mostrando ítems 1-6 de 6
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Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ... -
Brucellosis vaccines: assessment of brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export
Background: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella ... -
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ... -
Genetic analysis of Coprinopsis cinerea mutants with defects in fruiting body development
(Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, 2006) Contribución a congreso / Biltzarrerako ekarpenaFew genes have so far been cloned and characterized in fruiting of the heterothallic mushroom Coprinopsis cinerea. Fruiting body development normally occurs on the dikaryon. However, the binucleate state of the mycelium ... -
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ... -
Three classes of hemoglobins are required for optimal vegetative and reproductive growth of Lotus japonicus: genetic and biochemical characterization of LjGlb2-1
Legumes express two major types of hemoglobins, namely symbiotic (leghemoglobins) and non-symbiotic (phytoglobins), with the latter being categorized into three classes according to phylogeny and biochemistry. Using knockout ...