• ADAM12 is a potential therapeutic target regulated by hypomethylation in triple-negative breast cancer 

      Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Ruiz de Azúa, Yerani (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and currently lacks any effective targeted therapy. Since epigenetic alterations are a common event in TNBC, DNA methylation profiling can ...
    • Búsqueda de nuevos biomarcadores epigenéticos en cáncer de mama triple negativo 

      Ulazia Garmendia, Ane (2016)   Trabajo Fin de Máster/Master Amaierako Lana  OpenAccess
      Introducción El estudio de las alteraciones epigenéticas contribuye a la caracterización del subtipo triple negativo (TN) de cáncer de mama (CM). Objetivos Identificar genes diferencialmente metilados entre CM TN y ...
    • CDH22 hypermethylation is an independent prognostic biomarker in breast cancer 

      Martín Sánchez, Esperanza; Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero Setas, David (BioMed Central, 2017)   Artículo / Artikulua  OpenAccess
      Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ...
    • CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer 

      Martín Sánchez, Esperanza; Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Blanco Luquin, Idoia; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Pérez Janices, Noemi; Escors Murugarren, David; Megías, Diego (Impact Journals, 2017)   Artículo / Artikulua  OpenAccess
      The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation ...
    • A DNA methylation-based gene signature can predict triple-negative breast cancer diagnosis 

      Mendaza Lainez, Saioa Upna; Guerrero Setas, David; Monreal Santesteban, Iñaki; Ulazia Garmendia, Ane; Córdoba Iturriagagoitia, Alicia; Cruz, Susana de la; Martín Sánchez, Esperanza (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Triple-negative breast cancer (TNBC) is the most aggressive breast cancer (BC) subtype and lacks targeted treatment. It is diagnosed by the absence of immunohistochemical expression of several biomarkers, but this method ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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