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Increased C-X-C motif chemokine ligand 12 levels in cerebrospinal fluid as a candidate biomarker in sporadic amyotrophic lateral sclerosis
(MDPI, 2020)
info:eu-repo/semantics/article,
Sporadic amyotrophic lateral sclerosis (sALS) is a fatal progressive neurodegenerative disease affecting upper and lower motor neurons. Biomarkers are useful to facilitate the diagnosis and/or prognosis of patients and to ...
Identification of sociodemographic, biochemical and epigenetic biomarkers of hepatic steatosis in children with overweight or obesity
(2022)
info:eu-repo/semantics/doctoralThesis,
La obesidad infantil se ha convertido en unos de los problemas más graves en materia de salud pública del siglo XXI. En las últimas dos décadas, y de forma paralela a la epidemia de la obesidad infantil, diferentes ...
Biomarkers of delirium risk in older adults: a systematic review and meta-analysis
(Frontiers Media, 2023)
Artículo / Artikulua,
Delirium is a neuropsychiatric syndrome associated with increased morbidity and mortality in older patients. The aim of this study was to review predictive biomarkers of delirium in older patients to gain insights into the ...
Effect of immunology biomarkers associated with hip fracture and fracture risk in older adults
(BMC, 2023)
Artículo / Artikulua,
Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However, current clinical methods have limitations in accurately estimating fracture ...
Identificación de circRNAs como biomarcadores epigenéticos candidatos en la enfermedad de Alzheimer
(2022)
info:eu-repo/semantics/doctoralThesis,
La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa, crónica y, por el momento, irreversible que representa la primera causa de demencia relacionada con la edad. Su diagnóstico sigue siendo un reto. En los ...
Role of biomarkers for the diagnosis of prion diseases: a narrative review
(MDPI, 2022)
Artículo / Artikulua,
Prion diseases are progressive and irreversible neurodegenerative disorders with a low incidence (1.5–2 cases per million per year). Genetic (10–15%), acquired (anecdotal) and sporadic (85%) forms of the disease have been ...
Research of immunohistochemical biomarkers and Consensus Molecular Subtypes to characterize early-stage colorectal cancer patients
(2022)
info:eu-repo/semantics/doctoralThesis,
El trabajo de investigación llevado a cabo en esta tesis doctoral tiene como principal objetivo una mejor caracterización de los pacientes con cáncer de colon en estadios tempranos (estadio II y III). A pesar de que existen ...
Association of intrinsic capacity with incidence and mortality of cardiovascular disease: prospective study in UK Biobank
(Wiley, 2023)
Artículo / Artikulua,
Background: The World Health Organization proposed the concept of intrinsic capacity (IC; the composite of all the physical and mental capacities of the individual) as central for healthy ageing. However, little research ...
Revisiting skeletal myopathy and exercise training in heart failure: emerging role of myokines
(Elsevier, 2023)
Artículo / Artikulua,
Exercise intolerance remains a major unmet medical need in patients with heart failure (HF). Skeletal myopathy
is currently considered as the major limiting factor for exercise capacity in HF patients. On the other ...
PD-L1 in systemic immunity: unraveling its contribution to PD-1/PD-L1 blockade immunotherapy
(MDPI, 2020)
info:eu-repo/semantics/article,
The use of monoclonal antibodies targeting PD-1/PD-L1 axis completely changed anticancer treatment strategies. However, despite the significant improvement in overall survival and progression-free survival of patients ...