• Bile acids, FGF15/19 and liver regeneration: from mechanisms to clinical applications 

      Álvarez-Sola, Gloria; Uriarte, Iker; Latasa, Maria Ujue; Jiménez, Maddalen; Bárcena-Varela, Marina; Santamaría, Eva; Urtasun Alonso, Raquel Upna Orcid; Rodriguez-Ortigosa, Carlos; Prieto, Jesús; Berraondo, Pedro; Fernández-Barrena, Maite G.; Berasain, Carmen; Ávila, Matías A. (Elsevier, 2018)   Artículo / Artikulua
    • A combination of apple vinegar drink with Bacillus coagulans ameliorates high fat diet-induced body weight gain, insulin resistance and hepatic steatosis 

      Urtasun Alonso, Raquel Upna Orcid; Araña Ciordia, Miriam Upna Orcid; Pajares Villandiego, María Josefa Upna Orcid; Oneca, María Upna; Torre Hernández, Paloma Upna Orcid; Barajas Vélez, Miguel Ángel Upna Orcid; Encío Martínez, Ignacio Upna Orcid (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Obesity is a worldwide epidemic characterized by excessive fat accumulation, associated with multiple comorbidities and complications. Emerging evidence points to gut microbiome as a driving force in the pathogenesis of ...
    • Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma 

      Bárcena-Varela, Marina; Caruso, Stefano; Llerena, Susana; Álvarez-Sola, Gloria; Uriarte, Iker; Latasa, Maria Ujue; Urtasun Alonso, Raquel Upna Orcid; Rebouissou, Sandra; Álvarez Fraga, Laura; Jiménez, Maddalen; Santamaría, Eva; Rodriguez-Ortigosa, Carlos; Mazza, Giuseppe; Rombouts, Krista; San José Eneriz, Edurne; Rabal, Obdulia; Agirre, Xabier; Iraburu, María; Santos-Laso, Álvaro; Bañales, Jesús María; Zucman-Rossi, Jessica; Prósper, Felipe; Oyarzabal, Julen; Berasain, Carmen; Ávila, Matías A.; Fernández-Barrena, Maite G. (Mosby-Year Book, 2019)   Artículo / Artikulua
    • The epidermal growth factor receptor ligand amphiregulin protects from cholestatic liver injury and regulates bile acids synthesis 

      Santamaría, Eva; Rodríguez-Ortigosa, Carlos; Uriarte, Iker; Latasa, Maria Ujue; Urtasun Alonso, Raquel Upna Orcid; Álvarez-Sola, Gloria; Bárcena-Varela, Marina; Colyn, Leticia; Arcelus, Sara; Jiménez, Maddalen; Deutschmann, Kathleen; Peleteiro Vigil, Ana; Gómez Cambronero, Julian; Milkiewicz, Malgorzata; Milkiewicz, Piotr; Sangro, Bruno; Keitel, Verena; Monte, María J.; Marin, Jose J.G.; Fernández-Barrena, Maite G; Ávila, Matías A.; Berasain, Carmen (Mosby-Year Book, 2019)   Artículo / Artikulua
    • Lactiplantibacillus plantarum DSM20174 attenuates the progression of non-alcoholic fatty liver disease by modulating gut microbiota, improving metabolic risk factors, and attenuating adipose inflammation 

      Riezu Boj, José I.; Barajas Vélez, Miguel Ángel Upna Orcid; Pérez Sánchez, Tania Upna Orcid; Pajares Villandiego, María Josefa Upna Orcid; Araña Ciordia, Miriam Upna Orcid; Milagro, F. I. Upna; Urtasun Alonso, Raquel Upna Orcid (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, reaching epidemic proportions worldwide. Targeting the gut–adipose tissue–liver axis by modulating the gut microbiota can be a ...
    • Methods for analysis of specific DNA methylation status 

      Pajares Villandiego, María Josefa Upna Orcid; Palanca Ballester, Cora; Urtasun Alonso, Raquel Upna Orcid; Alemany Cosme, Ester; Lahoz, Agustín; Sandoval, Juan (Elevier, 2021)   Artículo / Artikulua  OpenAccess
      Methylation of CpG dinucleotides plays a crucial role in the regulation of gene expression and therefore in the development of different pathologies. Aberrant methylation has been associated to the majority of the diseases, ...
    • Nutritional interventions with bacillus coagulans improved glucose metabolism and hyperinsulinemia in mice with acute intermittent porphyria 

      Longo, Miriam; Jericó, Daniel; Córdoba, Karol M.; Riezu Boj, José I.; Urtasun Alonso, Raquel Upna Orcid; Solares, Isabel; Sampedro, Ana; Collantes, María; Peñuelas, Iván; Moreno Aliaga, María J.; Ávila, Matías A.; Di Pierro, Elena; Barajas Vélez, Miguel Ángel Upna Orcid; Milagro, F. I. Upna; Dongiovanni, Paola; Fontanellas, Antonio (MDPI, 2023)   Artículo / Artikulua  OpenAccess
      Acute intermittent porphyria (AIP) is a metabolic disorder caused by mutations in the porphobilinogen deaminase (PBGD) gene, encoding the third enzyme of the heme synthesis pathway. Although AIP is characterized by low ...
    • Pediococcus acidilactici pA1c® improves the beneficial effects of metformin treatment in type 2 diabetes by controlling glycaemia and modulating intestinal microbiota 

      Cabello Olmo, Miriam Upna Orcid; Oneca, María Upna; Urtasun Alonso, Raquel Upna Orcid; Pajares Villandiego, María Josefa Upna Orcid; Goñi Irigoyen, Saioa Upna Orcid; Riezu Boj, José I.; Milagro, F. I. Upna; Ayo, Josune; Encío Martínez, Ignacio Upna Orcid; Barajas Vélez, Miguel Ángel Upna Orcid; Araña Ciordia, Miriam Upna Orcid (MDPI, 2023)   Artículo / Artikulua  OpenAccess
      Type 2 diabetes (T2D) is a complex metabolic disease, which involves maintained hyperglycemia, mainly due to the development of an insulin resistance process. Metformin administration is the most prescribed treatment for ...
    • Role of postbiotics in diabetes mellitus: current knowledge and future perspectives 

      Cabello Olmo, Miriam Upna Orcid; Araña Ciordia, Miriam Upna Orcid; Urtasun Alonso, Raquel Upna Orcid; Encío Martínez, Ignacio Upna Orcid; Barajas Vélez, Miguel Ángel Upna Orcid (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      In the last decade, the gastrointestinal microbiota has been recognised as being essential for health. Indeed, several publications have documented the suitability of probiotics, prebiotics, and symbiotics in the management ...
    • Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins 

      Jiménez, Maddalen; Urtasun Alonso, Raquel Upna Orcid; Elizalde, María; Azkona, María; Latasa, Maria Ujue; Uriarte, Iker; Arechederra, María; Alignani, Diego; Bárcena-Varela, Marina; Álvarez-Sola, Gloria; Colyn, Leticia; Santamaría, Eva; Sangro, Bruno; Rodriguez-Ortigosa, Carlos; Fernández-Barrena, Maite G.; Ávila, Matías A.; Berasain, Carmen (Oxford University Press, 2019)   Artículo / Artikulua  OpenAccess
      Genome instability is related to disease development and carcinogenesis. DNA lesions are caused by genotoxic compounds but also by the dysregulation of fundamental processes like transcription, DNA replication and mitosis. ...
    • Splicing factor SLU7 prevents oxidative stress-mediated hepatocyte nuclear factor 4α degradation, preserving hepatic differentiation and protecting from liver damage 

      Gárate Rascón, María; Recalde, Miriam; Jiménez, Maddalen; Elizalde, María; Azkona, María; Uriarte, Iker; Latasa, Maria Ujue; Urtasun Alonso, Raquel Upna Orcid; Bilbao, Idoia; Sangro, Bruno; García Ruiz, Carmen; Fernández-Checa, José Carlos; Corrales, Fernando J.; Esquivel, Argitxu; Pineda Lucena, Antonio; Fernández-Barrena, Maite G.; Ávila, Matías A.; Arechederra, María; Berasain, Carmen (WileyAmerican Asociation for the Study of Liver Diseases, 2021)   Artículo / Artikulua  OpenAccess
      Background and Aims: Hepatocellular dedifferentiation is emerging as an important determinant in liver disease progression. Preservation of mature hepatocyte identity relies on a set of key genes, predominantly the ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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