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A narrative review of motor competence in children and adolescents: what we know and what we need to find out
Lack of physical activity is a global public health problem causing not only morbidity and premature mortality, but it is also a major economic burden worldwide. One of the cornerstones of a physically active lifestyle is ... -
A nationwide study of incidence and mortality due to traumatic brain injury in Ecuador
Objective: Traumatic brain injury (TBI) is a public health problem worldwide. Information regarding TBI from low- and middle-income countries is scarce. The objectives of this study are to determine the incidence, mortality ... -
Negative consequences of substance use in European university students: results from Project SNIPE
Background: University students are a risk group for heavy substance use and the experience of various potentially severe negative substance use consequences which may impact on their health, social, and academic functioning. ... -
Neighborhood environments and objectively measured physical activity in 11 countries
Purpose: Environmental changes are potentially effective population-level physical activity (PA) promotion strategies. However, robust multisite evidence to guide international action for developing activity-supportive ... -
Network analysis of neurobehavioral symptom patterns in an international sample of spanish-speakers with a history of COVID-19 and controls
Background: Psychometric network analysis provides a novel statistical approach allowing researchers to model clusters of related symptoms as a dynamic system. This study applied network analysis to investigate the ... -
Network-driven proteogenomics unveils an aging-related imbalance in the olfactory IκBα-NFκB p65 complex functionality in Tg2576 Alzheimer’s disease mouse model
Olfaction is often deregulated in Alzheimer’s disease (AD) patients, and is also impaired in transgenic Tg2576 AD mice, which overexpress the Swedish mutated form of human amyloid precursor protein (APP). However, little ... -
Neuroanatomical quantitative proteomics reveals common pathogenic biological routes between amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)
(1) Background: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders with an overlap in clinical presentation and neuropathology. Common and differential mechanisms leading ... -
Neuroestimulación de raíces sacras en el tratamiento de la incontinencia fecal grave: resultados de calidad de vida y funcionales a largo plazo
Fundamento. El objetivo fue conocer si la mejora funcional y de calidad de vida lograda con la neuroestimulación de raíces sacras (SNS) en pacientes con incontinencia fecal grave se mantiene a largo plazo. Material y ... -
Neuromuscular adaptations to combined strength and endurance training: order and time-of-day
The present study examined the effects of 24 weeks of morning vs. evening same-session combined strength (S) and endurance (E) training on neuromuscular and endurance performance. Fifty-one men were assigned to the morning ... -
Neuromuscular compartmentalization of the vastus medialis muscle: comparison of the activity of the vastus medialis obliquus and the vastus medialis longus by high density electromyography
Los estudios anatómicos describen que el músculo vasto medial (VM) se subdivide en dos componentes morfológicamente distintos, el vasto medial obliquus (VMO) y el vasto medial largo (VML). Sin embargo, existen discrepancias ... -
Neuropsychological functioning of individuals with coca paste use disorder
Background: Cocaine use has increased worldwide in recent years. However, the specific effects of smoking coca paste and its consequences on the cognitive functioning of individuals are unknown. The purposes of this study ... -
New formulation of a methylseleno-aspirin analog with anticancer activity towards colon cancer
Aspirin (ASA) has attracted wide interest of numerous scientists worldwide thanks to its chemopreventive and chemotherapeutic effects, particularly in colorectal cancer (CRC). Incorporation of selenium (Se) atom into ASA ... -
New in vivo approach to broaden the thioredoxin family interactome in chloroplasts
Post-translational redox modifications provide an important mechanism for the control of major cellular processes. Thioredoxins (Trxs), which are key actors in this regulatory mechanism, are ubiquitous proteins that catalyse ... -
New insights into immunotherapy strategies for treating autoimmune diabetes
Type 1 diabetes mellitus (T1D) is an autoimmune illness that affects millions of patients worldwide. The main characteristic of this disease is the destruction of pancreatic insulin-producing beta cells that occurs due to ... -
New patterns of information and communication technologies usage at work and their relationships with visual discomfort and musculoskeletal diseases: results of a cross-sectional study of Spanish organizations
This cross-sectional study analyses the usage patterns of the new communication and information technologies (ICTs) and their relationship with visual discomfort and musculoskeletal diseases in an intentional sample of ... -
Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
Objective: despite significant progresses in imaging and pathological evaluation, early differentiation between benign and malignant biliary strictures remains challenging. Endoscopic retrograde cholangiopancreatography ... -
Nivel educativo y la autonomía funcional en adultos que residen en Quito (Ecuador)
La incapacidad funcional del adulto asociada al envejecimiento poblacional genera un problema de salud pública. El objetivo de este artículo es estudiar la asociación existente entre el nivel educativo y la autonomía ... -
Non-suicidal self-injury experiences for adolescents who self-injured: contributions of Winnicott's psychoanalytic theory
Objective: to identify and analyze the elements present in non-suicidal self-injury experiences by adolescents who self-injured. Method: a qualitative research, with data collection conducted from August to October 2019 ... -
Normal-weight obesity is associated with increased cardiometabolic risk in young adults
Normal-weight obesity (NWO) has been shown to be associated with cardiometabolic dysfunction. However, little is known regarding this potential relationship in early adulthood. The aim of this study was to investigate the ... -
Normal-weight obesity is associated with poorer cardiometabolic profile and lower physical fitness levels in children and adolescents
Normal-weight obesity (NWO) syndrome has been shown to be associated with cardiometabolic dysfunction. However, little is known regarding this potential relationship in Latin American children and adolescents. The aim of ...