Listar Artículos de revista - Aldizkari artikuluak por autor "Gato Cañas, María"

Mostrando ítems 1-5 de 5

    • Early detection of hyperprogressive disease in non-small cell lung cancer by monitoring of systemic T cell dynamics 

      Arasanz Esteban, Hugo; Zuazo Ibarra, Miren Upna Orcid; Bocanegra Gondán, Ana Isabel; Gato Cañas, María; Martínez Aguillo, Maite; Morilla Ruiz, Idoia (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Hyperprogressive disease (HPD) is an adverse outcome of immunotherapy consisting of an acceleration of tumor growth associated with prompt clinical deterioration. The definitions based on radiological evaluation present ...

    • Molecular mechanisms of programmed cell death-1 dependent T cell suppression: relevance for immunotherapy 

      Zuazo Ibarra, Miren Upna Orcid; Gato Cañas, María; Llorente, Noelia; Ibáñez-Vea, María Upna Orcid; Arasanz Esteban, Hugo; Kochan, Grazyna; Escors Murugarren, David (AME Publishing, 2017)   Artículo / Artikulua  OpenAccess
      Programmed cell death-1 (PD1) has become a significant target for cancer immunotherapy. PD1 and its receptor programmed cell death 1 ligand 1 (PDL1) are key regulatory physiological immune checkpoints that maintain ...

    • PD1 signal transduction pathways in T cells 

      Arasanz Esteban, Hugo; Gato Cañas, María; Zuazo Ibarra, Miren Upna Orcid; Ibáñez-Vea, María Upna Orcid; Breckpot, Karine; Kochan, Grazyna; Escors Murugarren, David (Impact Journals, 2017)   Artículo / Artikulua  OpenAccess
      The use of immune checkpoint inhibitors for the treatment of cancer is revolutionizing oncology. Amongst these therapeutic agents, antibodies that block PD-L1/PD1 interactions between cancer cells and T cells are demonstrating ...

    • PDL1 signals through conserved sequence motifs to overcome interferon-mediated cytotoxicity 

      Gato Cañas, María; Zuazo Ibarra, Miren Upna Orcid; Arasanz Esteban, Hugo; Ibáñez-Vea, María Upna Orcid; Lorenzo, Laura; Fernandez-Hinojal, Gonzalo; Vera García, Ruth; Smerdou, Cristian; Martisova, Eva; Arozarena Martinicorena, Imanol; Wellbrock, Claudia; Llopiz, Diana; Ruiz, Marta; Sarobe, Pablo; Breckpot, Karine; Kochan, Grazyna; Escors Murugarren, David (Elsevier, 2017)   Artículo / Artikulua  OpenAccess
      PDL1 blockade produces remarkable clinical responses, thought to occur by T cell reactivation through prevention of PDL1-PD1 T cell inhibitory interactions. Here, we find that PDL1 cell-intrinsic signaling protects cancer ...

    • A proteomic atlas of lineage and cancer-polarized expression modules in myeloid cells modeling immunosuppressive tumor-infiltrating subsets 

      Blanco, Ester; Ibáñez-Vea, María Upna Orcid; Hernández, Carlos; Drici, Lylia; Martínez de Morentin Iribarren, Xabier; Gato Cañas, María; Ausín, Karina; Bocanegra Gondán, Ana Isabel; Zuazo Ibarra, Miren Upna Orcid; Chocarro, Luisa Upna Orcid; Arasanz Esteban, Hugo; Fernández Hinojal, Gonzalo; Fernández Irigoyen, Joaquín Upna Orcid; Smerdou, Cristian; Garnica, Maider; Echaide Górriz, Míriam; Fernández Rubio, Leticia; Morente Sancho, Pilar; Ramos-Castellanos, Pablo; Llopiz, Diana; Santamaría, Enrique; Larsen, Martin R.; Escors Murugarren, David; Kochan, Grazyna (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Monocytic and granulocytic myeloid-derived suppressor cells together with tumor-infiltrating macrophages constitute the main tumor-infiltrating immunosuppressive myeloid populations. Due to the phenotypic resemblance to ...
      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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