Listar Artículos de revista - Aldizkari artikuluak por autor "López Goñi, Ignacio"
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Brucellosis vaccines: assessment of brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export
González, David; Grilló Dolset, María Jesús; Miguel, María Jesús de; Ali, Tara; Arce Gorvel, Vilma; Delrue, Rose May; Conde Álvarez, Raquel; Muñoz Álvaro, Pilar María; López Goñi, Ignacio; Iriarte, Maite; Marín, Clara M.; Weintraub, Andrej; Widmalm, Goeran; Zygmunt, Michel; Letesson, Jean-Jacques; Gorvel, Jean-Pierre; Blasco, José María ; Moriyón Uría, Ignacio (Public Library of Science, 2008) Artículo / ArtikuluaBackground: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella ... -
BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence
Manterola, Lorea; Guzman-Verri, Caterina; Chaves Olarte, Esteban; Barquero-Calvo, Elías; Miguel, María Jesús de; Moriyón Uría, Ignacio; Grilló Dolset, María Jesús; López Goñi, Ignacio; Moreno, Edgardo (American Society for Microbiology, 2007) Artículo / ArtikuluaThe Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ... -
Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine
Mancilla, Marcos; Grilló Dolset, María Jesús; Miguel López, María Jesús de; López Goñi, Ignacio; San Román Aberasturi, Beatriz ; Zabalza Baranguá, Ana ; Moriyón Uría, Ignacio (BioMed Central, 2013) Artículo / ArtikuluaBrucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ... -
Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice
Soler Lloréns, Pedro; Gil Ramírez, Yolanda ; Zabalza Baranguá, Ana ; Iriarte, Maite; Conde Álvarez, Raquel; Zúñiga Ripa, Amaia; San Román Aberasturi, Beatriz ; Zygmunt, Michel; Vizcaíno, Nieves; Cloeckaert, Axel; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; López Goñi, Ignacio (BioMed Central, 2014) Artículo / ArtikuluaBrucella spp. are Gram-negative bacteria that behave as facultative intracellular parasites of a variety of mammals. This genus includes smooth (S) and rough (R) species that carry S and R lipopolysaccharides (LPS), ...