Listar Artículos de revista - Aldizkari artikuluak por tema "Cytoskeleton"

Deregulated transcription and proteostasis in adult mapt knockout mouse

Andrés Benito, Pol; Flores, África; Busquet-Areny, Sara; Carmona, Margarita; Ausín, Karina; Cartas Cejudo, Paz; Lachén Montes, Mercedes

; Río, José Antonio del; Fernández Irigoyen, Joaquín

; Santamaría, Enrique; Ferrer, Isidro (MDPI, 2023) Artículo / Artikulua

Transcriptomics and phosphoproteomics were carried out in the cerebral cortex of B6.Cg-Mapttm1(EGFP)Klt (tau knockout: tau-KO) and wild-type (WT) 12 month-old mice to learn about the effects of tau ablation. Compared with ...

Dysregulated protein phosphorylation: a determining condition in the continuum of brain aging and Alzheimer's disease

Ferrer, Isidro; Andrés Benito, Pol; Ausín, Karina; Pamplona, Reinald; Río, José Antonio del; Fernández Irigoyen, Joaquín

; Santamaría, Enrique (Wiley, 2021) Artículo / Artikulua

Tau hyperphosphorylation is the first step of neurofibrillary tangle (NFT) formation. In the present study, samples of the entorhinal cortex (EC) and frontal cortex area 8 (FC) of cases with NFT pathology classified as ...

Proteostatic modulation in brain aging without associated Alzheimer's disease-and age-related neuropathological changes

Andrés Benito, Pol; Íñigo-Marco, Ignacio; Brullas, Marta; Carmona, Margarita; Del Rio, José Antonio; Fernández Irigoyen, Joaquín

; Santamaría, Enrique; Povedano, Mónica; Ferrer, Isidro (Impact Journals, 2023) Artículo / Artikulua

Aims: (Phospho)proteomics of old-aged subjects without cognitive or behavioral symptoms, and without ADneuropathological changes and lacking any other neurodegenerative alteration will increase understanding about the ...