Recent Submissions

  • Plastidial phosphoglucose isomerase is an important determinant of seed yield through its involvement in gibberellin-mediated reproductive development and storage reserve biosynthesis in arabidopsis 

    Bahaji, Abdellatif; Almagro Zabalza, Goizeder Upna; Ezquer, Ignacio; Gámez Arcas, Samuel; Sánchez López, Ángela María; Muñoz Pérez, Francisco José; Barrio, Ramón José; Sampedro, M. Carmen; Diego, Nuria de; Spíchal, Lukás; Dolezal, Karel; Tarkowská, Danuse; Caporali, Elisabetta; Mendes, Marta Adelina; Baroja Fernández, Edurne Upna; Pozueta Romero, Javier Upna (American Society of Plant Biologists, 2018)   Artículo / Artikulua  OpenAccess
    The plastid-localized phosphoglucose isomerase isoform PGI1 is an important determinant of growth in Arabidopsis thaliana, likely due to its involvement in the biosynthesis of plastidial isoprenoid-derived hormones. Here, ...
  • Molecular signature of aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing 

    Varela Martínez, Endika; Abendaño, Naiara; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta María; Reina Arias, Ramsés Upna; Andrés Cara, Damián de Upna; Luján, Lluís; Jugo, Begoña M. (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
    There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ...
  • Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq 

    Bilbao Arribas, Martin; Abendaño, Naiara; Varela Martínez, Endika; Reina Arias, Ramsés Upna; Andrés Cara, Damián de Upna; Jugo, Begoña M. (BioMed Central, 2019)   Artículo / Artikulua  OpenAccess
    Background: MicroRNAs (miRNAs) are short endogenous, single-stranded, noncoding small RNA molecules of approximately 22 nucleotides in length. They regulate gene expression posttranscriptionally by silencing mRNA expression, ...
  • Proteomics analysis reveals non-controlled activation of photosynthesis and protein synthesis in a rice npp1 mutant under high temperature and elevated CO2 conditions 

    Inomata, Takuya; Baslam, Marouane; Masui, Takahiro; Koshu, Tsutomu; Takamatsu, Takeshi; Kaneko, Kentaro; Pozueta Romero, Javier Upna; Mitsui, Toshiaki (MDPI, 2018)   Artículo / Artikulua  OpenAccess
    Rice nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) catalyzes the hydrolytic breakdown of the pyrophosphate and phosphodiester bonds of a number of nucleotides including ADP-glucose and ATP. Under high temperature ...
  • Antagonistic pleiotropy in the bifunctional surface protein fadl (OmpP1) during adaptation of Haemophilus influenzae to chronic lung infection associated with chronic obstructive pulmonary disease 

    Moleres Apilluelo, Javier; Fernández Calvet, Ariadna; Ehrlich, Rachel L.; Martí, Sara; Pérez Regidor, Lucía; Euba, Begoña; Rodríguez Arce, Irene; Balashov, Sergey; Cuevas, Ester; Liñares, Josefina; Ardanuy, Carmen; Martín Santamaría, Sonsoles; Ehrlich, Garth D.; Mell, Joshua Chang; Garmendia, Junkal (American Society for Microbiology, 2018)   Artículo / Artikulua  OpenAccess
    Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects ...
  • A cAMP/CRP-controlled mechanism for the incorporation of extracellular ADP-glucose in Escherichia coli involving NupC and NupG nucleoside transporters 

    Almagro Zabalza, Goizeder Upna; Viale, Alejandro M. Upna; Montero Macarro, Manuel Upna; Muñoz Pérez, Francisco José; Baroja Fernández, Edurne Upna; Mori, Hirotada; Pozueta Romero, Javier Upna (Nature Research, 2018)   Artículo / Artikulua  OpenAccess
    ADP-glucose is the precursor of glycogen biosynthesis in bacteria, and a compound abundant in the starchy plant organs ingested by many mammals. Here we show that the enteric species Escherichia coli is capable of scavenging ...
  • Arabidopsis responds to Alternaria alternata volatiles by triggering pPG-independent mechanisms 

    Sánchez López, Ángela María; Bahaji, Abdellatif; Diego, Nuria de; Baslam, Marouane; Li, Jun; Muñoz Pérez, Francisco José; Almagro Zabalza, Goizeder Upna; García-Gómez, Pablo; Ameztoy del Amo, Kinia; Ricarte Bermejo, Adriana; Novák, Ondrej; Humplik, Jan F.; Spíchal, Lukás; Dolezal, Karel; Ciordia, Sergio; Mena, María Carmen; Navajas, Rosana; Baroja Fernández, Edurne Upna; Pozueta Romero, Javier Upna (American Society of Plant Biologists, 2016)   Artículo / Artikulua  OpenAccess
    Volatile compounds (VCs) emitted by phylogenetically diverse microorganisms (including plant pathogens and microbes that do not normally interact mutualistically with plants) promote photosynthesis, growth, and the ...
  • Volatile compounds emitted by diverse phytopathogenic microorganisms promote plant growth and flowering through cytokinin action 

    Sánchez López, Ángela María; Baslam, Marouane; Muñoz Pérez, Francisco José; Bahaji, Abdellatif; Almagro Zabalza, Goizeder Upna; Ricarte Bermejo, Adriana; García-Gómez, Pablo; Baroja Fernández, Edurne Upna; Pozueta Romero, Javier Upna (John Wiley & Sons, 2016)   Artículo / Artikulua  OpenAccess
    It is known that volatile emissions from some beneficial rhizosphere microorganisms promote plant growth. Here we show that volatile compounds (VCs) emitted by phylogenetically diverse rhizosphere and non-rhizhosphere ...
  • Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism 

    Cantón, Pablo Emiliano; Zanicthe Reyes, Esmeralda; Ruiz de Escudero Fuentemilla, Íñigo; Bravo, Alejandra; Soberón, Mario (Elsevier, 2011)   Artículo / Artikulua  OpenAccess
    Bacillus thuringiensis subsp. israelensis (Bti) produces at least four different crystal proteins that are specifically toxic to different mosquito species and that belong to two non-related family of toxins, Cry and ...
  • Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands 

    Tormo Más, María Ángeles; Mir, Ignacio; Shrestha, Archana; Tallent, Sandra M.; Campoy Sánchez, Susana; Lasa Uzcudun, Íñigo Upna; Barbé, Jordi; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Nature Research, 2010)   Artículo / Artikulua  OpenAccess
    Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of ∼15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently ...
  • The amino- and carboxyl-terminal fragments of the Bacillus thuringensis Cyt1Aa toxin have differential roles on toxin oligomerization and pore formation 

    Rodríguez Almazán, Claudia; Ruiz de Escudero Fuentemilla, Íñigo; Cantón, Pablo Emiliano; Muñoz Garay, Carlos; Pérez, Claudia; Gill, Sarjeet S.; Soberón, Mario; Bravo, Alejandra (American Chemical Society, 2011)   Artículo / Artikulua  OpenAccess
    The Cyt toxins produced by the bacteria Bacillus thuringiensis show insecticidal activity against some insects, mainly dipteran larvae, being able to kill mosquitoes and black flies. However, they also possess a general ...
  • Near-infrared fluorescence imaging as an alternative to bioluminescent bacteria to monitor biomaterial-associated infections 

    Dinjaski, Nina; Shalu, Suri; Valle Turrillas, Jaione Upna; Lehman, Susan M.; Lasa Uzcudun, Íñigo Upna; Prieto, María Auxiliadora; García, Andrés J. (Elsevier, 2014)   Artículo / Artikulua  OpenAccess
    Biomaterial-associated infection is one of the most common complications related with the implantation of any biomedical device. Several in vivo imaging platforms have emerged as powerful diagnostic tools to longitudinally ...
  • Overexpression of thioredoxin m in tobacco chloroplasts inhibits the protein kinase STN7 and alters photosynthetic performance 

    Ancín Rípodas, María Upna; Fernández San Millán, Alicia Upna; Larraya Reta, Luis María Upna; Morales Iribas, Fermín; Veramendi Charola, Jon Upna; Aranjuelo Michelena, Iker; Farrán Blanch, Inmaculada Upna (Oxford University Press, 2019)   Artículo / Artikulua  OpenAccess
    The activity of the protein kinase STN7, involved in phosphorylation of the light-harvesting complex II (LHCII) proteins, has been reported as being co-operatively regulated by the redox state of the plastoquinone pool ...
  • Calcium inhibits bap-dependent multicellular behavior in Staphylococcus aureus 

    Arrizubieta Balerdi, María Jesús; Toledo Arana, Alejandro Upna; Amorena Zabalza, Beatriz Upna; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2004)   Artículo / Artikulua  OpenAccess
    Bap (biofilm-associated protein) is a 254-kDa staphylococcal surface protein implicated in formation of biofilms by staphylococci isolated from chronic mastitis infections. The presence of potential EF-hand motifs in the ...
  • Bap, a Staphylococcus aureus surface protein involved in biofilm formation 

    Cucarella, Carme; Solano Goñi, Cristina Upna; Valle Turrillas, Jaione Upna; Amorena Zabalza, Beatriz Upna; Lasa Uzcudun, Íñigo Upna; Penadés, José R. (American Society for Microbiology, 2001)   Artículo / Artikulua  OpenAccess
    Identification of new genes involved in biofilm formation is needed to understand the molecular basis of strain variation and the pathogenic mechanisms implicated in chronic staphylococcal infections. A biofilm-producing ...
  • Conditional mutation of an essential putative glycoprotease eliminates autolysis in Staphylococcus aureus 

    Zheng, L.; Yu, C.; Bayles, K.; Lasa Uzcudun, Íñigo Upna; Ji, Y. (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
    Our previous studies demonstrated that a putative Staphylococcus aureus glycoprotease (Gcp) is essential for bacterial survival, indicating that Gcp may be a novel target for developing antibacterial agents. However, the ...
  • Glycogen phosphorylase, the product of the glgP Gene, catalyzes glycogen breakdown by removing glucose units from the nonreducing ends in Escherichia coli 

    Alonso-Casajus, Nora; Dauvillee, David; Viale, Alejandro M. Upna; Muñoz Pérez, Francisco José; Baroja Fernández, Edurne Upna; Morán Zorzano, María Teresa; Eydallin, Gustavo Upna; Ball, Steven; Pozueta Romero, Javier Upna (American Society for Microbiology, 2006)   Artículo / Artikulua  OpenAccess
    To understand the biological function of bacterial glycogen phosphorylase (GlgP), we have produced and characterized Escherichia coli cells with null or altered glgP expression. glgP deletion mutants (ΔglgP) totally lacked ...
  • B regulates IS256-mediated Staphylococcus aureus biofilm phenotypic variation 

    Valle Turrillas, Jaione Upna; Vergara Irigaray, Marta Upna; Merino, Nekane; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
    Biofilm formation in Staphylococcus aureus is subject to phase variation, and biofilm-negative derivatives emerge sporadically from a biofilm-positive bacterial population. To date, the only known mechanism for generating ...
  • Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins 

    Tormo Más, María Ángeles; Ferrer, María Desamparados; Maiques, Elisa; Ubeda, Carles; Selva, Laura; Lasa Uzcudun, Íñigo Upna; Calvete, Juan J.; Novick, Richard P.; Penadés, José R. (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
    Staphylococcus aureus pathogenicity islands (SaPIs) have an intimate relationship with temperate staphylococcal phages. During phage growth, SaPIs are induced to replicate and are efficiently encapsidated into special small ...
  • Protein A-mediated multicellular behavior in Staphylococcus aureus 

    Merino, Nekane; Toledo Arana, Alejandro Upna; Vergara Irigaray, Marta Upna; Valle Turrillas, Jaione Upna; Solano Goñi, Cristina Upna; Calvo, Enrique; Lopez, Juan Antonio; Foster, Timothy J.; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
    The capacity of Staphylococcus aureus to form biofilms on host tissues and implanted medical devices is one of the major virulence traits underlying persistent and chronic infections. The matrix in which S. aureus cells ...

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