Now showing items 1-20 of 185

    • Adenosine diphosphate glucose pyrophosphatase: a plastidial phosphodiesterase that prevents starch biosynthesis 

      Rodríguez López, Milagros Upna; Baroja Fernández, Edurne Upna Orcid; Zandueta Criado, Aitor Upna; Pozueta Romero, Javier Upna Orcid (National Academy of Sciences, 2000)   Artículo / Artikulua  OpenAccess
      A distinct phosphodiesterasic activity (EC 3.1.4) was found in both mono- and dicotyledonous plants that catalyzes the hydrolytic breakdown of ADPglucose (ADPG) to produce equimolar amounts of glucose-1-phosphate and AMP. ...
    • Adenosine diphosphate sugar pyrophosphatase prevents glycogen biosynthesis in Escherichia coli 

      Moreno Bruna, Beatriz Upna; Baroja Fernández, Edurne Upna Orcid; Muñoz Pérez, Francisco José Upna; Bastarrica Berasategui, Ainara Upna; Zandueta Criado, Aitor Upna; Rodríguez López, Milagros Upna; Lasa Uzcudun, Íñigo Upna Orcid; Akazawa, Takashi; Pozueta Romero, Javier Upna Orcid (National Academy of Sciences, 2001)   Artículo / Artikulua  OpenAccess
      An adenosine diphosphate sugar pyrophosphatase (ASPPase, EC 3.6.1.21) has been characterized by using Escherichia coli. This enzyme, whose activities in the cell are inversely correlated with the intracellular glycogen ...
    • The amino- and carboxyl-terminal fragments of the Bacillus thuringensis Cyt1Aa toxin have differential roles on toxin oligomerization and pore formation 

      Rodríguez Almazán, Claudia; Ruiz de Escudero Fuentemilla, Íñigo Upna Orcid; Cantón, Pablo Emiliano; Muñoz Garay, Carlos; Pérez, Claudia; Gill, Sarjeet S.; Soberón, Mario; Bravo, Alejandra (American Chemical Society, 2011)   Artículo / Artikulua  OpenAccess
      The Cyt toxins produced by the bacteria Bacillus thuringiensis show insecticidal activity against some insects, mainly dipteran larvae, being able to kill mosquitoes and black flies. However, they also possess a general ...
    • Amyloid structures as biofilm matrix scaffolds 

      Taglialegna, Agustina Upna; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (American Society for Microbiology, 2016)   Artículo / Artikulua  OpenAccess
      Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward the recognition of amyloid fibers as common building block structures that confer stability to the exopolysaccharide matrix. ...
    • Analagous population structures for two alphabaculoviruses highlight a functional role for deletion mutants 

      Serrano García, Amaya Upna; Williams, Trevor Upna; Simón de Goñi, Oihane Upna Orcid; López Ferber, Miguel; Caballero Murillo, Primitivo Upna Orcid; Muñoz Labiano, Delia Upna Orcid (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      A natural Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) isolate from Florida shares a strikingly similar genotypic composition to that of a natural Spodoptera frugiperda MNPV (SfMNPV) isolate from Nicaragua. ...
    • Analysis of the role of the LH92_11085 gene of a biofilm hyper-producing Acinetobacter baumannii strain on biofilm formation and attachment to eukaryotic cells 

      Álvarez Fraga, Laura; Pérez, Astrid; Rumbo Feal, Soraya; Merino, María; Valle Turrillas, Jaione Upna Orcid (Taylor & Francis, 2016)   Artículo / Artikulua  OpenAccess
      Acinetobacter baumannii is a nosocomial pathogen that has a considerable ability to survive in the hospital environment partly due to its capacity to form biofilms. The first step in the process of establishing an infection ...
    • Antagonistic pleiotropy in the bifunctional surface protein fadl (OmpP1) during adaptation of Haemophilus influenzae to chronic lung infection associated with chronic obstructive pulmonary disease 

      Moleres Apilluelo, Javier Upna Orcid; Fernández Calvet, Ariadna Upna; Ehrlich, Rachel L.; Martí, Sara; Pérez Regidor, Lucía; Euba, Begoña; Rodríguez Arce, Irene Upna; Balashov, Sergey; Cuevas, Ester; Liñares, Josefina; Ardanuy, Carmen; Martín Santamaría, Sonsoles; Ehrlich, Garth D.; Mell, Joshua Chang; Garmendia García, Juncal (American Society for Microbiology, 2018)   Artículo / Artikulua  OpenAccess
      Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects ...
    • Apoptosis, toll-like, RIG-I-like and NOD-like receptors are pathways jointly induced by diverse respiratory bacterial and viral pathogens 

      Martínez, Isidoro; Oliveros, Juan C.; Cuesta, Isabel; Barrera, Jorge de la; Ausina, Vicente; Casals, Cristina; Lorenzo, Alba de; García, Ernesto; García Fojeda, Belén; Garmendia García, Juncal; González Nicolau, Mar; Lacoma, Alicia; Menéndez, Margarita; Moranta, David; Nieto, Amelia; Ortín, Juan; Pérez González, Alicia; Prat, Cristina; Ramos Sevillano, Elisa; Regueiro, Verónica; Rodríguez Frandsen, Ariel; Solís, Dolores; Yuste, José E.; Bengoechea Alonso, José Antonio; Melero, José A. (Frontiers Media, 2017)   Artículo / Artikulua  OpenAccess
      Lower respiratory tract infections are among the top five leading causes of human death. Fighting these infections is therefore a world health priority. Searching for induced alterations in host gene expression shared by ...
    • Arabidopsis responds to Alternaria alternata volatiles by triggering pPG-independent mechanisms 

      Sánchez López, Ángela María; Bahaji, Abdellatif Upna Orcid; Diego, Nuria de; Baslam, Marouane Upna; Li, Jun Upna; Muñoz Pérez, Francisco José Upna; Almagro Zabalza, Goizeder Upna Orcid; García Gómez, Pablo; Ameztoy del Amo, Kinia Upna Orcid; Ricarte Bermejo, Adriana Upna Orcid; Novák, Ondrej; Humplik, Jan F.; Spíchal, Lukás; Dolezal, Karel; Ciordia, Sergio; Mena, María Carmen; Navajas, Rosana; Baroja Fernández, Edurne Upna Orcid; Pozueta Romero, Javier Upna Orcid (American Society of Plant Biologists, 2016)   Artículo / Artikulua  OpenAccess
      Volatile compounds (VCs) emitted by phylogenetically diverse microorganisms (including plant pathogens and microbes that do not normally interact mutualistically with plants) promote photosynthesis, growth, and the ...
    • B regulates IS256-mediated Staphylococcus aureus biofilm phenotypic variation 

      Valle Turrillas, Jaione Upna Orcid; Vergara Irigaray, Marta Upna; Merino, Nekane Upna; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
      Biofilm formation in Staphylococcus aureus is subject to phase variation, and biofilm-negative derivatives emerge sporadically from a biofilm-positive bacterial population. To date, the only known mechanism for generating ...
    • Bacillus thuringiensis toxins: an overview of their biocidal activity 

      Palma Dovis, Leopoldo Upna Orcid; Muñoz Labiano, Delia Upna Orcid; Berry, Colin; Murillo Martínez, Jesús Upna Orcid; Caballero Murillo, Primitivo Upna Orcid (MDPI, 2014)   Artículo / Artikulua  OpenAccess
      Bacillus thuringiensis (Bt) is a Gram positive, spore-forming bacterium that synthesizes parasporal crystalline inclusions containing Cry and Cyt proteins, some of which are toxic against a wide range of insect orders, ...
    • Baculovirus-induced climbing behavior favors intraspecific necrophagy and efficient disease transmission in Spodoptera exigua 

      Rebolledo, Dulce; Lasa, Rodrigo; Guevara, Roger; Murillo Pérez, Rosa Upna Orcid; Williams, Trevor Upna (Public Library of Science, 2015)   Artículo / Artikulua  OpenAccess
      Shortly prior to death, many species of Lepidoptera infected with nucleopolyhedrovirus climb upwards on the host plant. This results in improved dissemination of viral occlusion bodies over plant foliage and an increased ...
    • Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor 

      Valle Turrillas, Jaione Upna Orcid; Latasa Osta, Cristina Upna; Gil Puig, Carmen Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Solano Goñi, Cristina Upna Orcid; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
    • Bap, a Staphylococcus aureus surface protein involved in biofilm formation 

      Cucarella, Carme; Solano Goñi, Cristina Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Amorena Zabalza, Beatriz Upna; Lasa Uzcudun, Íñigo Upna Orcid; Penadés, José R. (American Society for Microbiology, 2001)   Artículo / Artikulua  OpenAccess
      Identification of new genes involved in biofilm formation is needed to understand the molecular basis of strain variation and the pathogenic mechanisms implicated in chronic staphylococcal infections. A biofilm-producing ...
    • Base pairing interaction between 5′- and 3′-UTRs controls icaR mRNA translation in Staphylococcus aureus 

      Ruiz de los Mozos Aliaga, Igor Upna; Vergara Irigaray, Marta Upna; Segura, Víctor; Villanueva San Martín, Maite Upna Orcid; Bitarte, Nerea Upna; Saramago, Margarida; Domingues, Susana; Arraiano, Cecilia M.; Fechter, Pierre; Romby, Pascale; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Toledo Arana, Alejandro Upna Orcid (Public Library of Science, 2013)   Artículo / Artikulua  OpenAccess
      The presence of regulatory sequences in the 39 untranslated region (39-UTR) of eukaryotic mRNAs controlling RNA stability and translation efficiency is widely recognized. In contrast, the relevance of 39-UTRs in bacterial ...
    • Beta-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus 

      Maiques, Elisa; Ubeda, Carles; Campoy Sánchez, Susana; Salvador, Noelia; Lasa Uzcudun, Íñigo Upna Orcid; Novick, Richard P.; Barbé, Jordi; Penadés, José R. (American Society for Microbiology, 2006)   Artículo / Artikulua  OpenAccess
      Antibiotics that interfere with DNA replication and cell viability activate the SOS response. In Staphylococcus aureus, the antibiotic-induced SOS response promotes replication and high-frequency horizontal transfer ...
    • Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism 

      Cantón, Pablo Emiliano; Zanicthe Reyes, Esmeralda; Ruiz de Escudero Fuentemilla, Íñigo Upna Orcid; Bravo, Alejandra; Soberón, Mario (Elsevier, 2011)   Artículo / Artikulua  OpenAccess
      Bacillus thuringiensis subsp. israelensis (Bti) produces at least four different crystal proteins that are specifically toxic to different mosquito species and that belong to two non-related family of toxins, Cry and ...
    • Biofilm dispersion and quorum sensing 

      Solano Goñi, Cristina Upna Orcid; Echeverz Sarasúa, Maite Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Elsevier, 2014)   Artículo / Artikulua  OpenAccess
      Biofilm development and quorum sensing are closely interconnected processes. Biofilm formation is a cooperative group behaviour that involves bacterial populations living embedded in a self produced extracellular matrix. ...
    • Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection 

      Gil Puig, Carmen Upna Orcid; Solano Goñi, Cristina Upna Orcid; Burgui Erice, Saioa Upna Orcid; Latasa Osta, Cristina Upna; García Martínez, Begoña Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (American Society for Microbiology, 2014)   Artículo / Artikulua  OpenAccess
      The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ...
    • Biofilm switch and immune response determinants at early stages of infection 

      Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; García Martínez, Begoña Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Elsevier (Cell Press), 2013)   Artículo / Artikulua  OpenAccess
      Biofilm development is recognized as a major virulence factor underlying most chronic bacterial infections. When a biofilm community is established, planktonic cells growing in the surroundings of a tissue switch to a ...