Buscar
Mostrando ítems 1-8 de 8
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
(Public Library of Science, 2011)
Artículo / Artikulua,
The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ...
Brucellosis vaccines: assessment of brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export
(Public Library of Science, 2008)
Artículo / Artikulua,
Background: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella ...
Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice
(BioMed Central, 2014)
info:eu-repo/semantics/article,
Brucella spp. are Gram-negative bacteria that behave as facultative intracellular parasites of a variety of mammals. This genus includes smooth (S) and rough (R) species that carry S and R lipopolysaccharides (LPS), ...
BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence
(American Society for Microbiology, 2007)
info:eu-repo/semantics/article,
The Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ...
What have we learned from brucellosis in the mouse model?
(BioMed Central, 2012)
Artículo / Artikulua,
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine
(BioMed Central, 2013)
Artículo / Artikulua,
Brucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(Public Library of Science, 2012)
Artículo / Artikulua,
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
Identification of lptA, lpxE, and lpxO, three genes involved in the remodeling of Brucella cell envelope
(Frontiers Media, 2018)
info:eu-repo/semantics/article,
The brucellae are facultative intracellular bacteria that cause a worldwide extended zoonosis. One of the pathogenicity mechanisms of these bacteria is their ability to avoid rapid recognition by innate immunity because ...