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RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
(Oxford University Press, 2011)
Artículo / Artikulua,
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
Draft genome sequences of two bacillus thuringiensis strains and characterization of a putative 41.9-kDa insecticidal toxin
(MDPI, 2014)
Artículo / Artikulua,
In this work, we report the genome sequencing of two Bacillus thuringiensis
strains using Illumina next-generation sequencing technology (NGS). Strain Hu4-2, toxic
to many lepidopteran pest species and to some mosquitoes, ...
Nontypable haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates
(Public Library of Science, 2011)
Artículo / Artikulua,
Non-typable Haemophilus influenzae (NTHi) is a Gram negative pathogen that causes acute respiratory infections and is associated with the progression of chronic respiratory diseases. Previous studies have established the ...
What have we learned from brucellosis in the mouse model?
(BioMed Central, 2012)
Artículo / Artikulua,
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(Public Library of Science, 2012)
Artículo / Artikulua,
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
(Public Library of Science, 2011)
Artículo / Artikulua,
The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ...
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine
(BioMed Central, 2013)
Artículo / Artikulua,
Brucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ...
Spatial distribution and risk factors of brucellosis in Iberian wild ungulates
(BioMed Central, 2010)
Artículo / Artikulua,
Background: The role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. The aim of this work was to determine the aetiology, apparent prevalence, spatial distribution ...
Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in Escherichia coli
(Oxford University Press, 2010)
Artículo / Artikulua,
Using a systematic and comprehensive gene expression library (the ASKA library), we have carried out a genome-wide screening of the genes whose increased plasmid-directed expression affected glycogen metabolism in Escherichia ...