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    Influence of a commercial antithrombotic filter on the caval blood flow during neutra and valsalva maneuver

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    Date
    2017
    Author
    Nicolás, M. 
    Lucea, B. 
    Laborda, A. 
    Peña, Estefanía 
    Malvè, Mauro Upna Orcid
    Version
    Acceso abierto / Sarbide irekia
    Type
    Artículo / Artikulua
    Version
    Versión aceptada / Onetsi den bertsioa
    Project Identifier
    MINECO//DPI2013-44391-P/ES/ 
    ES/1PE/DPI2016-76630 
    Impact
     
     
     
    10.1115/1.4035983
     
     
     
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    Abstract
    Anticoagulants are the treatment of choice for pulmonary embolism. When these fail or are contraindicated, vena cava filters are effective devices for preventing clots from the legs from migrating to the lung. Many uncertainties exist when a filter is inserted, especially during physiological activity such as normal breathing and the Valsalva maneuver. These activities are often connected with fi ... [++]
    Anticoagulants are the treatment of choice for pulmonary embolism. When these fail or are contraindicated, vena cava filters are effective devices for preventing clots from the legs from migrating to the lung. Many uncertainties exist when a filter is inserted, especially during physiological activity such as normal breathing and the Valsalva maneuver. These activities are often connected with filter migration and vena cava damage due to the various related vein geometrical configurations. In this work, we analyzed the response of the vena cava during normal breathing and Valsalva maneuver, for a healthy vena cava and after insertion of a commercial Günther-Tulip® filter. Validated computational fluid dynamics (CFD) and patient specific data are used for analyzing blood flow inside the vena cava during these maneuvers. While during normal breathing, the vena cava flow can be considered almost stationary with a very low pressure gradient, during Valsalva the extravascular pressure compresses the vena cava resulting in a drastic reduction of the vein section, a global flow decrease through the cava but increasing the velocity magnitude. This change in the section is altered by the presence of the filter which forces the section of the vena cava before the renal veins to keep open. The effect of the presence of the filter is investigated during these maneuvers showing changes in wall shear stress and velocity patterns. [--]
    Subject
    Blood flow, Filters, Flow (Dynamics), Pressure
     
    Publisher
    ASME
    Published in
    Journal of Medical Devices, 2017, 11(3): 031002
    Departament
    Universidad Pública de Navarra. Departamento de Ingeniería Mecánica, Energética y de Materiales / Nafarroako Unibertsitate Publikoa. Mekanika, Energetika eta Materialen Ingeniaritza Saila
     
    Publisher version
    https://doi.org/10.1115/1.4035983
    URI
    https://hdl.handle.net/2454/38411
    Sponsorship
    This study was supported by the CIBER-BBN financed by the Instituto de Salud Carlos III, by the Spanish Ministry of Science and Technology through the Research Projects Nos. DPI-2010-20746-C03-01 and DPI-2013-44391-P and by the Spanish Ministry of Economy and Competitiveness through the Research Project No. DPI-2016-76630-C2-1-R. The experimental study was supported by the Instituto de Salud Carlos III, through the Research Project No. PI08/1424 and was performed by the Minimally Invasive Techniques Research Group (GITMI) of Aragon Government.
    Appears in Collections
    • Artículos de revista - Aldizkari artikuluak [4598]
    • Artículos de revista DIMEM - MEMIS Aldizkari artikuluak [66]
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