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dc.creatorAdin Urtasun, Aritzes_ES
dc.creatorMartínez Bello, Daniel Adyroes_ES
dc.creatorLópez Quílez, Antonioes_ES
dc.creatorUgarte Martínez, María Doloreses_ES
dc.date.accessioned2020-11-18T09:18:28Z
dc.date.available2020-11-18T09:18:28Z
dc.date.issued2018
dc.identifier.issn1932-6203
dc.identifier.urihttps://hdl.handle.net/2454/38713
dc.description.abstractRisk maps of dengue disease offer to the public health officers a tool to model disease risk in space and time. We analyzed the geographical distribution of relative incidence risk of dengue disease in a high incidence city from Colombia, and its evolution in time during the period January 2009—December 2015, identifying regional effects at different levels of spatial aggregations. Cases of dengue disease were geocoded and spatially allocated to census sectors, and temporally aggregated by epidemiological periods. The census sectors are nested in administrative divisions defined as communes, configuring two levels of spatial aggregation for the dengue cases. Spatio-temporal models including census sector and commune-level spatially structured random effects were fitted to estimate dengue incidence relative risks using the integrated nested Laplace approximation (INLA) technique. The final selected model included two-level spatial random effects, a global structured temporal random effect, and a census sector-level interaction term. Risk maps by epidemiological period and risk profiles by census sector were generated from the modeling process, showing the transmission dynamics of the disease. All the census sectors in the city displayed high risk at some epidemiological period in the outbreak periods. Relative risk estimation of dengue disease using INLA offered a quick and powerful method for parameter estimation and inference.en
dc.description.sponsorshipThis work was supported by grants from the Spanish Ministry of Economy and Competitiveness (projects MTM2014-51992-R-MDU- and MTM2016-77501-P -ALQ-, jointly financed with the European Regional Development Fund), the Spanish Ministry of Economy, Industry, and Competitiveness (MTM2017-82553-R jointly financed with the European Regional Development Fund (FEDER). MDU, AA), and the Colombian Administrative Department of Science and Technology (grant 646-2014 for doctoral studies abroad) DAMB.en
dc.format.extent17 p.
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherPublic Library of Scienceen
dc.relation.ispartofPLoS ONE, 2018, 13(9): e0203382en
dc.rights© 2018 Adin et al. This is an open_x000D_ access article distributed under the terms of the_x000D_ Creative Commons Attribution License, which_x000D_ permits unrestricted use, distribution, and_x000D_ reproduction in any medium, provided the original_x000D_ author and source are credited.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectDengue feveren
dc.subjectCensusen
dc.subjectMedical risk factorsen
dc.subjectEpidemiologyen
dc.subjectDisease surveillanceen
dc.subjectColombiaen
dc.subjectPublic and occupational healthen
dc.subjectUrban areasen
dc.titleTwo-level resolution of relative risk of dengue disease in a hyperendemic city of Colombiaen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeArtículo / Artikuluaes
dc.contributor.departmentEstadística, Informática y Matemáticases_ES
dc.contributor.departmentEstatistika, Informatika eta Matematikaeu
dc.contributor.departmentInstitute for Advanced Materials and Mathematics - INAMAT2es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.identifier.doi10.1371/journal.pone.0203382
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO//MTM2014-51992-R/ES/en
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/1PE/MTM2016-77501-Pen
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MTM2017-82553-R/ES/en
dc.relation.publisherversionhttps://doi.org/10.1371/journal.pone.0203382
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.type.versionVersión publicada / Argitaratu den bertsioaes


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© 2018 Adin et al. This is an open_x000D_ access article distributed under the terms of the_x000D_ Creative Commons Attribution License, which_x000D_ permits unrestricted use, distribution, and_x000D_ reproduction in any medium, provided the original_x000D_ author and source are credited.
La licencia del ítem se describe como © 2018 Adin et al. This is an open_x000D_ access article distributed under the terms of the_x000D_ Creative Commons Attribution License, which_x000D_ permits unrestricted use, distribution, and_x000D_ reproduction in any medium, provided the original_x000D_ author and source are credited.

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