Browsing by Author "Lecumberri Villamediana, Pablo"
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Publication Open Access Agreement between an inertial measurement unit (IMU) algorithm and a photoelectric system for analysing spatiotemporal variables during overground and treadmill running(Taylor & Francis, 2025-05-21) Miqueleiz Erburu, Unai; Aguado Jiménez, Roberto; Lecumberri Villamediana, Pablo; Gorostiaga Ayestarán, Esteban; Ciencias de la Salud; Osasun ZientziakThe aim of this study was to assess the agreement between running stride variables measured simultaneously with an inertial sensor (MTw IMU) using a specific algorithm, and a floor-based photoelectric (Optojump; OJ) system among well-trained endurance runners, during overground and treadmill runs at speeds ranging from 9 to 21 km∙h-1. Five different filter settings (from 0_0 to 4_4) were used with the OJ to detect the contact event, based on the number of LEDs (from 1 to 5). No significant differences (p > 0.05) were found between the two devices in any of the stride variables when the 4_4 filter was implemented using the OJ. The agreement was good for contact time (CT) and flight time (FT) [r = 0.81–0.93; Typical error of the estimate (TEE%) = 3.2–7.5%], whereas for stride frequency (SF), stride length (SL) and stride time (ST) the agreement was almost perfect (r = 0.91–0.99; TEE% = 0.2–1.7%). The agreement worsened as the number of activated LEDs used to detect the contact event decreased. This suggests that the tested inertial sensor using a specific algorithm can achieve highly precise measurement of spatiotemporal parameters during both overground and treadmill running, compared to the OJ (4_4) system.Publication Open Access Assessment of asymmetric leg loading before and after total hip arthroplasty using instrumented shoes(BioMed Central, 2014) Martínez Ramírez, Alicia; Weenk, Dirk; Lecumberri Villamediana, Pablo; Verdonschot, Nico; Pakvis, Dean; Veltink, Peter H.; Matemáticas; MatematikaBackground: Total hip arthroplasty is a successful surgical treatment in patients with osteoarthritis of the hip. Different questionnaires are used by the clinicians to assess functional capacity and the patient's pain, despite these questionnaires are known to be subjective. Furthermore, many studies agree that kinematic and kinetic parameters are crucial to evaluate and to provide useful information about the patient’s evolution for clinicians and rehabilitation specialists. However, these quantities can currently only be obtained in a fully equipped gait laboratory. Instrumented shoes can quantify gait velocity, kinetic, kinematic and symmetry parameters. The aim of this study was to investigate whether the instrumented shoes is a sufficiently sensitive instrument to show differences in mobility performance before and after total hip arthroplasty. Methods: In this study, patients undergoing total hip arthroplasty were measured before and 6–8 months after total hip arthroplasty. Both measurement sessions include 2 functional mobility tasks while the subject was wearing instrumented shoes. Before each measurement the Harris Hip Score and the Traditional Western Ontario and McMaster Universities osteoarthritis index were administered as well. Results: The stance time and the average vertical ground reaction force measured with the instrumented shoes during walking, and their symmetry index, showed significant differences before and after total hip arthroplasty. However, the data obtained with the sit to stand test did not reveal this improvement after surgery. Conclusions: Our results show that inter-limb asymmetry during a walking activity can be evaluated with the instrumented shoes before and after total hip arthroplasty in an outpatient clinical setting.Publication Open Access Asymmetric white matter degeneration in amyotrophic lateral sclerosis: a diffusion kurtosis imaging study of motor and extra-motor pathways(Frontiers Media, 2025-04-25) Quizhpilema Cedeño, Juan Carlos; Legarda, Ane; Hidalgo, José Manuel ; Lecumberri Villamediana, Pablo; Jericó Pascual, Ivonne; Cabada Giadás, María Teresa; Ciencias de la Salud; Osasun Zientziak; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoa eta Telekomunikazio Ingeniaritza; Gobierno de Navarra / Nafarroako GobernuaBackground: Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that lacks effective early biomarkers. This study investigated the potential of diffusion kurtosis imaging (DKI) as a non-invasive biomarker for detecting and monitoring ALS progression through a comprehensive analysis of white matter alterations. Methods: We performed a cross-sectional analysis of magnetic resonance images with advanced diffusion imaging techniques in ALS patients recruited from a neurodegenerative consultation service over a 3-year period and healthy controls. Our methodology employed multi-shell multi-tissue constrained spherical deconvolution (MSMT-CSD) for tract reconstruction and diffusion kurtosis imaging for microstructural analysis. The study focused particularly on the corticospinal tract and associated pathways, utilizing both tract-specific Bundle Analytics (BUAN) and whole-brain Tract-Based Spatial Statistics (TBSS) approaches. Results: The study included 33 ALS patients and 37 controls with no significant differences in age or gender. ALS patients predominantly presented with spinal onset and exhibited moderate functional impairment (ALSFRS-R: 39.09 ± 5). Whole-brain TBSS revealed widespread white matter alterations, with increased MD, RD, and AD, and decreased FA notably in the corona radiata, internal capsule, and corticospinal tracts. Detailed fiber tracking of the corticospinal tracts showed significant microstructural changes, with the left CST displaying pronounced increases in MD and AD alongside reduced FA, while the right CST exhibited distinctive regional variations. Additionally, analyses of the frontopontine and parietopontine tracts uncovered further alterations in diffusion metrics. Despite imaging findings, clinical-radiological correlations with functional scores and disease progression were not statistically significant. Conclusions: This study explores DKI as a potential biomarker for ALS pathology, revealing microstructural changes in both motor and extra-motor pathways. Using whole-brain TBSS analysis and tractography with DIPY, we identified an asymmetric pattern of degeneration and involvement of integrative neural networks, providing new insights into ALS pathophysiology. These findings contribute to our understanding of the complex structural alterations in ALS and suggest that DKI-derived metrics may have utility in characterizing the disease process.Publication Open Access Cálculo y visualización de rangos articulares de las extremidades superiores en tiempo real(2019) Oreja Murillo, Elisa; Lecumberri Villamediana, Pablo; Gómez Fernández, Marisol; Escuela Técnica Superior de Ingenieros Industriales y de Telecomunicación; Telekomunikazio eta Industria Ingeniarien Goi Mailako Eskola TeknikoaEl objetivo principal de este proyecto es ayudar, gracias a la tecnología de la que hoy en día disponemos, a rehabilitar a pacientes con dificultades motoras en alguna de las extremidades de su cuerpo. En este caso, nos centraremos en los brazos, teniendo en cuenta para su estudio las articulaciones del hombro y del codo. En este proyecto concreto, el objetivo principal es obtener y visualizar rangos articulares de las extremidades superiores. Para ello se usan los datos proporcionados por tres sensores inerciales colocados en el pecho, brazo y antebrazo. Así, se puede observar cómo progresa la persona que padece una lesión o alteración motora. Además, los especialistas sanitarios pueden interpretar fácilmente los resultados obtenidos y decidir cuál es la rehabilitación más adecuada para cada paciente.Publication Open Access Computation of greatest common divisor for the blind deconvolution of transient impulsive signals(Universitat Politècnica de Catalunya, 2005) Lecumberri Villamediana, Pablo; Gómez Fernández, Marisol; Carlosena García, Alfonso; Matemáticas; Ingeniería Eléctrica y Electrónica; Matematika; Ingeniaritza Elektrikoa eta ElektronikoaWe propose a new blind deconvolution method for transient impulsive signals in a single input – multiple output (SIMO) system. The method exploits the data redundancy inherent to SIMO multichannel systems to obtain an estimation of the input signal. The method is built upon the assumptions of finite-length signals and channel diversity.Publication Open Access Consistency of sex-based differences between treadmill and overground running using an inertial measurement unit (IMU)(Elsevier, 2024-06-19) Miqueleiz Erburu, Unai; Aguado Jiménez, Roberto; Lecumberri Villamediana, Pablo; Gorostiaga Ayestarán, Esteban; Ciencias de la Salud; Osasun Zientziak; Universidad Publica de Navarra / Nafarroako Unibertsitate PublikoaDifferences in running gait between treadmill and overground running has been subject of study, while consistency of group differences between running surfaces has not been previously analysed. This study examined both the differences between running surfaces and the consistency of sex-based differences between surfaces in some spatiotemporal and kinematic variables measured by an inertial measurement unit fastened over the lumbar spine. Thirty-two (sixteen females) endurance runners firstly performed overground and then treadmill (1 % inclination) runs at speeds between 9-21 km.h-1. Males showed lower flight time (FT) [moderate effect size (ES)] during treadmill running compared to overground, while females showed greater stride frequency (SF) (moderate ES), lower stride length (SL) (moderate ES), FT (moderate ES), and vertical (VT) trunk displacement (moderate ES), as well as greater medio-lateral (ML) trunk displacement (moderate ES). No differences in CT between surfaces were found (trivial to small). Furthermore, all the sex-differences were consistent between treadmill and overground running: Males showed lower SF (large and moderate ES, respectively), greater SL (large and moderate ES) and CT (moderate and large ES), lower FT (large ES), greater VT displacement (moderate to large ES), and lower ML displacement (moderate ES) than females. These results may be of interest to carefully transfer the running gait analyses between surfaces depending on sex.Publication Restricted Creación de una base de datos de señales biomecánicas con una unidad inercial(2009) Castillo Latorre, Ignacio del; Lecumberri Villamediana, Pablo; Martínez Ramírez, Alicia; Escuela Técnica Superior de Ingenieros Industriales y de Telecomunicación; Telekomunikazio eta Industria Ingeniarien Goi Mailako Eskola Teknikoa; Matemáticas; MatematikaPublication Open Access Design of low-cost smart accelerometers(Universitat Politècnica de Catalunya, 2005) Carlosena García, Alfonso; López Martín, Antonio; Massarotto, Marco; Cruz Blas, Carlos Aristóteles de la; Lecumberri Villamediana, Pablo; Gómez Fernández, Marisol; Pintor Borobia, Jesús María; Gárriz Sanz, Sergio; Ingeniería Eléctrica y Electrónica; Matemáticas; Ingeniería Mecánica, Energética y de Materiales; Ingeniaritza Elektrikoa eta Elektronikoa; Matematika; Mekanika, Energetika eta Materialen IngeniaritzaThe goal of this project is to design a low-cost smart accelerometer, making use of a piezoelectric element as basic sensing material, and adding a mixed-mode conditioning circuit.Publication Restricted Evaluación de la reconstrucción iterativa de la tomografía por emisión de positrones (PET): influencia sobre la calidad de imagen en estudios cerebrales(2006) Zabalza Iturri, Leyre; Gómez Fernández, Marisol; Lecumberri Villamediana, Pablo; Escuela Técnica Superior de Ingenieros Industriales y de Telecomunicación; Telekomunikazio eta Industria Ingeniarien Goi Mailako Eskola Teknikoa; Ingeniería Matemática e Informática; Matematika eta Informatika IngeniaritzaPublication Open Access An evaluation of the 30-s chair stand test in older adults: frailty detection based on kinematic parameters from a single inertial unit(BioMed Central, 2013) Millor Muruzábal, Nora; Lecumberri Villamediana, Pablo; Gómez Fernández, Marisol; Martínez Ramírez, Alicia; Izquierdo Redín, Mikel; Matemáticas; Ciencias de la Salud; Matematika; Osasun Zientziak; Gobierno de Navarra / Nafarroako GobernuaBackground: A growing interest in frailty syndrome exists because it is regarded as a major predictor of co-morbidities and mortality in older populations. Nevertheless, frailty assessment has been controversial, particularly when identifying this syndrome in a community setting. Performance tests such as the 30-second chair stand test (30-s CST) are a cornerstone for detecting early declines in functional independence. Additionally, recent advances in body-fixed sensors have enhanced the sensors’ ability to automatically and accurately evaluate kinematic parameters related to a specific movement performance. The purpose of this study is to use this new technology to obtain kinematic parameters that can identify frailty in an aged population through the performance the 30-s CST. Methods: Eighteen adults with a mean age of 54 years, as well as sixteen pre-frail and thirteen frail patients with mean ages of 78 and 85 years, respectively, performed the 30-s CST while threir trunk movements were measured by a sensor-unit at vertebra L3. Sit-stand-sit cycles were determined using both acceleration and orientation information to detect failed attempts. Movement-related phases (i.e. impulse, stand-up, and sit-down) were differentiated based on seat off and seat on events. Finally, the kinematic parameters of the impulse, stand-up and sit-down phases were obtained to identify potential differences across the three frailty groups. Results: For the stand-up and sit-down phases, velocity peaks and “modified impulse” parameters clearly differentiated subjects with different frailty levels (p < 0.001). The trunk orientation range during the impulse phase was also able to classify a subject according to his frail syndrome (p < 0.001). Furthermore, these parameters derived from the inertial units (IUs) are sensitive enough to detect frailty differences not registered by the number of completed cycles which is the standard test outcome. Conclusions: This study shows that IUs can enhance the information gained from tests currently used in clinical practice, such as the 30-s CST. Parameters such as velocity peaks, impulse, and orientation range are able to differentiate between adults and older populations with different frailty levels. This study indicates that early frailty detection could be possible in clinical environments, and the subsequent interventions to correct these disabilities could be prescribed before further degradation occurs.Publication Open Access Frailty assessment based on trunk kinematic parameters during walking(BioMed Central, 2015) Martínez Ramírez, Alicia; Martinikorena Aranburu, Ion; Gómez Fernández, Marisol; Lecumberri Villamediana, Pablo; Millor Muruzábal, Nora; Rodríguez Mañas, Leocadio; García García, Francisco José; Izquierdo Redín, Mikel; Matemáticas; MatematikaBackground: Physical frailty has become the center of attention of basic, clinical and demographic research due to its incidence level and gravity of adverse outcomes with age. Frailty syndrome is estimated to affect 20 % of the population older than 75 years. Thus, one of the greatest current challenges in this field is to identify parameters that can discriminate between vulnerable and robust subjects. Gait analysis has been widely used to predict frailty. The aim of the present study was to investigate whether a collection of parameters extracted from the trunk acceleration signals could provide additional accurate information about frailty syndrome. Methods: A total of 718 subjects from an elderly population (319 males, 399 females; age: 75.4 ± 6.1 years, mass: 71.8 ± 12.4 kg, height: 158 ± 6 cm) volunteered to participate in this study. The subjects completed a 3-m walk test at their own gait velocity. Kinematic data were acquired from a tri-axial inertial orientation tracker. Findings: The spatio-temporal and frequency parameters measured in this study with an inertial sensor are related to gait disorders and showed significant differences among groups (frail, pre-frail and robust). A selection of those parameters improves frailty classification obtained to gait velocity, compared to classification model based on gait velocity solely. Interpretation: Gait parameters simultaneously used with gait velocity are able to provide useful information for a more accurate frailty classification. Moreover, this technique could improve the early detection of pre-frail status, allowing clinicians to perform measurements outside of a laboratory environment with the potential to prescribe a treatment for reversing their physical decline.Publication Open Access Motor abnormalities and cognitive impairment in first-episode psychosis patients, their unaffected siblings and healthy controls(Elsevier, 2018) Cuesta, Manuel J.; Moreno-Izco, Lucía; Ribeiro Fernández, María; López-Ilundain, José M.; Lecumberri Villamediana, Pablo; Cabada Giadás, María Teresa; Lorente Omeñaca, Ruth; Sánchez Torres, Ana María; Gómez Fernández, Marisol; Peralta Martín, Víctor; Ciencias de la Salud; Osasun Zientziak; Matemáticas; MatematikaMotor abnormalities (MAs) may be already evidenced long before the beginning of illness and are highly prevalent in psychosis. However, the extent to which the whole range of MAs are related to cognitive impairment in psychosis remains understudied. This study aimed to examine comparatively the relationships between the whole range of motor abnormalities and cognitive impairments in the first-episode of psychosis (FEP), their unaffected siblings and healthy control subjects. Fifty FEP patients, 21 of their healthy siblings and 24 age- and sex matched healthy controls were included. Motor assessment included catatonic, extrapyramidal and neurological soft signs (NSS) by means of standardized instruments. An exhaustive neuropsychological battery was also performed to extract the 7 cognitive dimensions of MATRICS initiative. Higher scores on NSS but not on extrapyramidal and catatonic signs showed significant associations with worse cognitive performance in the three study groups. However, the pattern of associations regarding specific cognitive functions was different among the three groups. Moreover, extrapyramidal signs showed significant associations with cognitive impairment only in FEP patients but not in their unaffected siblings and healthy controls. Catatonic signs did not show any significant association with cognitive functioning in the three study groups. These findings add evidence to the associations between motor abnormalities, particularly NSS and extrapyramidal signs, and cognitive impairment in first-episode psychosis patients. In addition, our results suggest that the specific pattern of associations between MAs and cognitive functioning is different in FEP patients from those of the unaffected siblings and healthy subjects.Publication Open Access Multichannel blind deconvolution of impulsive signals(2005) Lecumberri Villamediana, Pablo; Gómez Fernández, Marisol; Carlosena García, Alfonso; Matemáticas; Ingeniería Eléctrica y Electrónica; Matematika; Ingeniaritza Elektrikoa eta ElektronikoaIn this communication, the problem of blind deconvolution of transient, impulsive signals in a multichannel environment is addressed. This kind of signals arise naturally, or are used as external excitation, in many mechanical and acoustical systems and can only be observed indirectly, after propagation through the medium. Blind deconvolution or identi cation methods published to date are not suitable for recovering these sources or the system response, as identi ability conditions are not met. We fully develop here a deterministic subspace method for the blind deconvolution in a multichannel environment which does not impose any restrictions on the excitation signals or on the impulse response of propagation channels, apart from nite length and channel diversity. The method is also extended to cope with signals in noisy environments.Publication Open Access Pre-operative ambulatory measurement of asymmetric lower limb loading during walking in total hip arthroplasty patients(BioMed Central, 2013) Martínez Ramírez, Alicia; Weenk, Dirk; Lecumberri Villamediana, Pablo; Verdonschot, Nico; Pakvis, Dean; Veltink, Peter H.; Matemáticas; Matematika; Universidad Pública de Navarra / Nafarroako Unibertsitate PublikoaBackground: Total hip arthroplasty is a successful surgical procedure to treat hip osteoarthritis. Clinicians use different questionnaires to assess the patient’s pain and functional capacity. Furthermore, they assess the quality of gait in a very global way. This clinical evaluation usually shows significant improvement after total hip arthroplasty, however, does not provide objective, quantifiable information about the movement patterns underlying the functional capacity, which can currently only be obtained in a gait laboratory. Instrumented force shoes can quantify gait velocity, ground reaction forces and the gait pattern easily in an outpatient setting. The main goal of this study was to investigate how mobility characteristics during walking, relate to gait velocity and questionnaire outcomes of patients with hip osteoarthritis in an outpatient setting. Methods: 22 patients with primary osteoarthritis of the hip selected for a total hip arthroplasty participated in this study. For each patient the Harris Hip Score, the Traditional Western Ontario and the McMaster Universities osteoarthritis index were administered. Subsequently, the patients were instructed to walk through the corridor while wearing instrumented shoes. The gait velocity estimated with the instrumented force shoes was validated measuring the time required to walk a distance of 10 m using a stopwatch and a measuring tape as a reference system. A regression analysis between spatial, temporal, ground reaction force parameters, including asymmetry, and the gait velocity and the questionnaires outcomes was performed. Results: The velocity estimated with the instrumented shoes did not differ significantly from the velocity measured independently. Although gait parameters correlated significantly with velocity, symmetry index parameters were not correlated with velocity. These symmetry index parameters show significant inter-limb asymmetry during walking. No correlation was found between any of the variables studied and questionnaires outcomes. Conclusion: Inter-limb asymmetry can be evaluated with the instrumented shoes supplying important additional information about the individual gait pattern, which is not represented by gait velocity and questionnaires usually used. Therefore, this new ambulatory measurement system is able to provide complementary information to gait velocity and questionnaires outcomes to assess the functional capacity of patients with hip osteoarthritis.Publication Open Access Reliability of Xsens inertial measurement unit in measuring trunk accelerations: a sex-based differences study during incremental treadmill running(Frontiers Media, 2024) Miqueleiz Erburu, Unai; Aguado Jiménez, Roberto; Lecumberri Villamediana, Pablo; García-Tabar, Ibai; Gorostiaga Ayestarán, Esteban; Ciencias de la Salud; Osasun ZientziakIntroduction: Inertial measurement units (IMUs) are utilized to measure trunk acceleration variables related to both running performances and rehabilitation purposes. This study examined both the reliability and sex-based differences of these variables during an incremental treadmill running test. Methods: Eighteen endurance runners performed a test–retest on different days, and 30 runners (15 females) were recruited to analyze sex-based differences. Mediolateral (ML) and vertical (VT) trunk displacement and root mean square (RMS) accelerations were analyzed at 9, 15, and 21 km·h−1. Results: No significant differences were found between test-retests [effect size (ES)<0.50)]. Higher intraclass correlation coefficients (ICCs) were found in the trunk displacement (0.85-0.96) compared to the RMS-based variables (0.71–0.94). Male runners showed greater VT displacement (ES = 0.90–1.0), while female runners displayed greater ML displacement, RMS ML and anteroposterior (AP), and resultant euclidean scalar (RES) (ES = 0.83–1.9). Discussion: The IMU was found reliable for the analysis of the studied trunk acceleration-based variables. This is the first study that reports different results concerning acceleration (RMS) and trunk displacement variables for a same axis in the analysis of sex-based differences.Publication Open Access Sprint mechanics evaluation using inertial sensor-based technology: a laboratory validation study(Wiley, 2018) Setuain Chourraut, Igor; Lecumberri Villamediana, Pablo; Ahtiainen, J. P.; Mero, A. A.; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun ZientziakAdvances in micro‐electromechanical systems have turned magnetic inertial measurement units (MIMUs) into a suitable tool for vertical jumping biomechanical evaluation. Thus, this study aimed to determine whether appropriate reliability and agreement reports could also be obtained when analyzing 20‐m sprint mechanics. Four bouts of 20‐m sprints were evaluated to determine whether the data provided by a MIMU placed at the lumbar spine could reliably assess sprint mechanics and to examine the validity of the MIMU sensor compared to force plate recordings. Maximal power (P0), force (F0), and velocity (V0), as well as other mechanical determinants of sprint performance associated with the force‐velocity, power‐velocity, and ratio of forces‐velocity, such as applied horizontal force loss (Sfv) and decrease in ratio of forces (Drf), were calculated and compared between instrumentations. Extremely large‐to‐very large correlation levels between MIMU sensor‐based sprint mechanics variables and force plate recordings were obtained (mean±SD, force plate vs MIMU; V0, 8.61±0.85 vs 8.42±0.69; F0, 383±110 vs 391±103; P0, 873±246 vs 799±241; Sfv, −44.6±12.7 vs −46.2±10.7), ranging from 0.88 to 0.94, except for Drf, which showed weak‐to‐moderate correlation level (r=.45; −6.32±1.08 vs −5.76±0.68). Step‐averaged force values measured with both systems were highly correlated (r=.88), with a regression slope close to the identity (1.01). Bland and Altman graphical representation showed a no random distribution of measured force values. Finally, very large‐to‐extremely large retest correlation coefficients were found for the intertrial reliability of MIMU measurements of sprint performance variables (r value ranging from .72 to .96). Therefore, MIMUs showed appropriate validity and reliability values for 20‐m sprint performance variables.Publication Embargo Validación del sistema de análisis de la marcha JERO con el sistema gold-standard GAITRite en población adulta(2024) Roldán Escuchuri, Jesús; Lecumberri Villamediana, Pablo; Millor Muruzábal, Nora; Escuela Técnica Superior de Ingeniería Agronómica y Biociencias; Nekazaritzako Ingeniaritzako eta Biozientzietako Goi Mailako Eskola TeknikoaMedir la capacidad de la marcha en personas es crucial no solo para evaluar la función física, sino también para: diagnosticar lesiones en diferentes grupos de población, monitorizar la progresión de enfermedades y evaluar la efectividad de tratamientos con el objetivo final de apoyar la independencia funcional y la calidad de vida de los individuos. Al igual que un análisis de sangre es útil para conocer nuestro estado de salud general, los parámetros espaciales y temporales de la marcha proporcionan una información valiosa del estado funcional de una persona.