Dpto. Automática y Computación - Automatika eta Konputazioa Saila

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Browsing Dpto. Automática y Computación - Automatika eta Konputazioa Saila by Department/Institute "Estadística, Informática y Matemáticas"

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    PublicationOpen Access
    d-XC integrals: on the generalization of the expanded form of the Choquet integral by restricted dissimilarity functions and their applications
    (IEEE, 2022) Wieczynski, Jonata; Fumanal Idocin, Javier; Lucca, Giancarlo; Borges, Eduardo N.; Da Cruz Asmus, Tiago; Emmendorfer, Leonardo R.; Bustince Sola, Humberto; Pereira Dimuro, Graçaliz; Automática y Computación; Automatika eta Konputazioa; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
    Restricted dissimilarity functions (RDFs) were introduced to overcome problems resulting from the adoption of the standard difference. Based on those RDFs, Bustince et al. introduced a generalization of the Choquet integral (CI), called d-Choquet integral, where the authors replaced standard differences with RDFs, providing interesting theoretical results. Motivated by such worthy properties, joint with the excellent performance in applications of other generalizations of the CI (using its expanded form, mainly), this paper introduces a generalization of the expanded form of the standard Choquet integral (X-CI) based on RDFs, which we named d-XC integrals. We present not only relevant theoretical results but also two examples of applications. We apply d-XC integrals in two problems in decision making, namely a supplier selection problem (which is a multi-criteria decision making problem) and a classification problem in signal processing, based on motor-imagery brain-computer interface (MI-BCI). We found that two d-XC integrals provided better results when compared to the original CI in the supplier selection problem. Besides that, one of the d-XC integrals performed better than any previous MI-BCI results obtained with this framework in the considered signal processing problem.
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    PublicationOpen Access
    Is the phenotype designation by PSP-MDS criteria stable throughout the disease course and consistent with tau distribution?
    (Frontiers Media, 2022) Sánchez Ruiz de Gordoa, Javier; Zelaya Huerta, María Victoria; Tellechea-Aramburo, Paula; Acha Santamaría, Blanca; Roldán, Miren; López Molina, Carlos; Coca, Valle; Galbete Jiménez, Arkaitz; Mendióroz Iriarte, Maite; Erro Aguirre, María Elena; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
    Introduction: the MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do not discriminate the phenotype diversity. Our purpose was to search for anatomopathological differences among PSP phenotypes resulting from the application of the MDS-PSP criteria comparing with the previous ones. Methods: thirty-four PSP cases from a single brain bank were retrospectively classified according to the criteria used by Respondek et al. in 2014 and the PSP-MDS criteria at 3 years (MDS-3y), 6 years (MDS-6y) and at the last clinical evaluation before death (MDS-last). Semiquantitative measurement of total, cortical and subcortical tau load was compared. For comparative analysis, PSP-Richardson syndrome and PSP postural instability were grouped (PSP-RS/PI) as well as the PSP atypical cortical phenotypes (PSP-Cx). Results: applying the Respondek's criteria, PSP phenotypes were distributed as follow: 55.9% PSP-RS/PI, 26.5% PSP-Cx, 11.8% PSP-Parkinsonism (PSP-P), and 5.9% PSP-Cerebellum. PSP-RS/PI and PSP-Cx had a higher total tau load than PSP-P; PSP-Cx showed a higher cortical tau load than PSP-RS/PI and PSP-P; and PSP-RS/PI had a higher subcortical tau load than PSP-P. Applying the MDS-3y, MDS-6y and MDS-last criteria; the PSP-RS/PI group increased (67.6, 70.6 and 70.6% respectively) whereas the PSP-Cx group decreased (8.8, and 8.8 and 11.8%). Then, only differences in total and subcortical tau burden between PSP-RS/PI and PSP-P were observed. Interpretation: after the retrospective application of the new MDS-PSP criteria, total and subcortical tau load is higher in PSP-RS/PI than in PSP-P whereas no other differences in tau load between phenotypes were found, as a consequence of the loss of phenotypic diversity.