Malanda Trigueros, Armando

Loading...
Profile Picture

Email Address

Birth Date

Job Title

Last Name

Malanda Trigueros

First Name

Armando

person.page.departamento

Ingeniería Eléctrica, Electrónica y de Comunicación

person.page.instituteName

ISC. Institute of Smart Cities

person.page.observainves

person.page.upna

Name

Search Results

Now showing 1 - 10 of 22
  • PublicationOpen Access
    Sliding window averaging in normal and pathological motor unit action potential trains
    (Elsevier, 2018) Malanda Trigueros, Armando; Navallas Irujo, Javier; Rodríguez Falces, Javier; Porta Cuéllar, Sonia; Fernández Martínez, Miguel; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    Objective: To evaluate the performance of a recently proposed motor unit action potential (MUAP) averaging method based on a sliding window, and compare it with relevant published methods in normal and pathological muscles. Methods: Three versions of the method (with different window lengths) were compared to three relevant published methods in terms of signal analysis-based merit figures and MUAP waveform parameters used in the clinical practice. 218 MUAP trains recorded from normal, myopathic, subacute neurogenic and chronic neurogenic muscles were analysed. Percentage scores of the cases in which the methods obtained the best performance or a performance not significantly worse than the best were computed. Results: For signal processing figures of merit, the three versions of the new method performed better (with scores of 100, 86.6 and 66.7%) than the other three methods (66.7, 25 and 0%, respectively). In terms of MUAP waveform parameters, the new method also performed better (100, 95.8 and 91.7%) than the other methods (83.3, 37.5 and 25%). Conclusions: For the types of normal and pathological muscle studied, the sliding window approach extracted more accurate and reliable MUAP curves than other existing methods. Significance: The new method can be of service in quantitative EMG.
  • PublicationOpen Access
    Independent component analysis as a tool to eliminate artifacts in EEG. A quantitative study
    (Lippincott, Williams & Wilkins, 2003) Iriarte, Jorge; Urrestarazu, Elena; Valencia Ustárroz, Miguel; Alegre, Manuel; Malanda Trigueros, Armando; Viteri, César; Artieda, Julio; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa
    Independent component analysis (ICA) is a novel technique that calculates independent components from mixed signals. A hypothetical clinical application is to remove artifacts in EEG. The goal of this study was to apply ICA to standard EEG recordings to eliminate well-known artifacts, thus quantifying its efficacy in an objective way. Eighty samples of recordings with spikes and evident artifacts of electrocardiogram (EKG), eye movements, 50-Hz interference, muscle, or electrode artifact were studied. ICA components were calculated using the Joint Approximate Diagonalization of Eigen-matrices (JADE) algorithm. The signal was reconstructed excluding those components related to the artifacts. A normalized correlation coefficient was used as a measure of the changes caused by the suppression of these components. ICA produced an evident clearing-up of signals in all the samples. The morphology and the topography of the spike were very similar before and after the removal of the artifacts. The correlation coefficient showed that the rest of the signal did not change significantly. Two examiners independently looked at the samples to identify the changes in the morphology and location of the discharge and the artifacts. In conclusion, ICA proved to be a useful tool to clean artifacts in short EEG samples, without having the disadvantages associated with the digital filters. The distortion of the interictal activity measured by correlation analysis was minimal.
  • PublicationOpen Access
    A masked least-squares smoothing procedure for artifact reduction in scanning-EMG recordings
    (Springer, 2018) Corera Orzanco, Íñigo; Eciolaza Ferrando, Adrián; Rubio Zamora, Oliver; Malanda Trigueros, Armando; Rodríguez Falces, Javier; Navallas Irujo, Javier; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    Scanning-EMG is an electrophysiological technique in which the electrical activity of the motor unit is recorded at multiple points along a corridor crossing the motor unit territory. Correct analysis of the scanning-EMG signal requires prior elimination of interference from nearby motor units. Although the traditional processing based on the median filtering is effective in removing such interference, it distorts the physiological waveform of the scanning-EMG signal. In this study, we describe a new scanning-EMG signal processing algorithm that preserves the physiological signal waveform while effectively removing interference from other motor units. To obtain a cleaned-up version of the scanning signal, the masked least-squares smoothing (MLSS) algorithm recalculates and replaces each sample value of the signal using a least-squares smoothing in the spatial dimension, taking into account the information of only those samples that are not contaminated with activity of other motor units. The performance of the new algorithm with simulated scanning-EMG signals is studied and compared with the performance of the median algorithm and tested with real scanning signals. Results show that the MLSS algorithm distorts the waveform of the scanning-EMG signal much less than the median algorithm (approximately 3.5 dB gain), being at the same time very effective at removing interference components.
  • PublicationOpen Access
    EMG probability density function: a new way to look at EMG signal filling from single motor unit potential to full interference pattern
    (IEEE, 2023) Navallas Irujo, Javier; Eciolaza Ferrando, Adrián; Mariscal Aguilar, Cristina; Malanda Trigueros, Armando; Rodríguez Falces, Javier; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    An analytical derivation of the EMG signal's amplitude probability density function (EMG PDF) is presented and used to study how an EMG signal builds-up, or fills, as the degree of muscle contraction increases. The EMG PDF is found to change from a semi-degenerate distribution to a Laplacian-like distribution and finally to a Gaussian-like distribution. We present a measure, the EMG filling factor, to quantify the degree to which an EMG signal has been built-up. This factor is calculated from the ratio of two non-central moments of the rectified EMG signal. The curve of the EMG filling factor as a function of the mean rectified amplitude shows a progressive and mostly linear increase during early recruitment, and saturation is observed when the EMG signal distribution becomes approximately Gaussian. Having presented the analytical tools used to derive the EMG PDF, we demonstrate the usefulness of the EMG filling factor and curve in studies with both simulated signals and real signals obtained from the tibialis anterior muscle of 10 subjects. Both simulated and real EMG filling curves start within the 0.2 to 0.35 range and rapidly rise towards 0.5 (Laplacian) before stabilizing at around 0.637 (Gaussian). Filling curves for the real signals consistently followed this pattern (100% repeatability within trials in 100% of the subjects). The theory of EMG signal filling derived in this work provides (a) an analytically consistent derivation of the EMG PDF as a function of motor unit potentials and motor unit firing patterns; (b) an explanation of the change in the EMG PDF according to degree of muscle contraction; and (c) a way (the EMG filling factor) to quantify the degree to which an EMG signal has been built-up.
  • PublicationOpen Access
    Association of intrinsic capacity with incidence and mortality of cardiovascular disease: prospective study in UK Biobank
    (Wiley, 2023) Ramírez Vélez, Robinson; Iriarte-Fernández, María; Santafé Rodrigo, Guzmán; Malanda Trigueros, Armando; Beard, John R.; García Hermoso, Antonio; Izquierdo Redín, Mikel; Ciencias de la Salud; Estadística, Informática y Matemáticas; Ingeniería Eléctrica, Electrónica y de Comunicación; Institute for Advanced Materials and Mathematics - INAMAT2; Osasun Zientziak; Estatistika, Informatika eta Matematika; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
    Background: The World Health Organization proposed the concept of intrinsic capacity (IC; the composite of all the physical and mental capacities of the individual) as central for healthy ageing. However, little research has investigated the interaction and joint associations of IC with cardiovascular disease (CVD) incidence and CVD mortality in middle- and older-aged adults. Methods: Using data from 443 130 UK Biobank participants, we analysed seven biomarkers capturing the level of functioning of five domains of IC to calculate a total IC score (ranging from 0 [better IC] to +4 points [poor IC]). Associations between IC score and incidence of six long-term CVD conditions (hypertension, stroke/transient ischaemic attack stroke, peripheral vascular disease, atrial fibrillation/flutter, coronary artery disease and heart failure), and grouped mortality from these conditions were estimated using Cox proportional models, with a 1-year landmark analysis to triangulate the findings. Results: Over 10.6 years of follow-up, CVD morbidity grouped (n = 384 380 participants for the final analytic sample) was associated with IC scores (0 to +4): mean hazard ratio (HR) [95% confidence interval, CI] 1.11 [1.08–1.14], 1.20 [1.16–1.24], 1.29 [1.23–1.36] and 1.56 [1.45–1.59] in men (C-index = 0.68), and 1.17 [1.13–1.20], 1.30 [1.26–1.36], 1.52 [1.45–1.59] and 1.78 [1.67–1.89] in women (C-index = 0.70). In regard to mortality, our results indicated that the higher IC score (+4 points) was associated with a significant increase in subsequent CVD mortality (mean HR [95% CI]: 2.10 [1.81–2.43] in men [C-index = 0.75] and 2.29 [1.85–2.84] in women [C-index = 0.78]). Results of all sensitivity analyses by full sample, sex and age categories were largely consistent independent of major confounding factors (P < 0.001). Conclusions: IC deficit score is a powerful predictor of functional trajectories and vulnerabilities of the individual in relation to CVD incidence and premature death. Monitoring an individual's IC score may provide an early-warning system to initiate preventive efforts.
  • PublicationOpen Access
    Masked least-squares averaging in processing of scanning-EMG recordings with multiple-discharges
    (Springer, 2020) Corera Orzanco, Íñigo; Malanda Trigueros, Armando; Rodríguez Falces, Javier; Navallas Irujo, Javier; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa
    Removing artifacts from nearby motor units is one of the main objectives when processing scanning-EMG recordings. Methods such as median filtering or masked least-squares smoothing (MLSS) can be used to eliminate artifacts in recordings with just one discharge of the motor unit potential (MUP) at each location. However, more effective artifact removal can be achieved if several discharges per position are recorded. In this case, processing usually involves averaging the discharges available at each position and then applying a median filter in the spatial dimension. The main drawback of this approach is that the median filter tends to distort the signal waveform. In this paper, we present a new algorithm that operates on multiple discharges simultaneously and in the spatial dimension. We refer to this algorithm as the multi masked least-squares smoothing (MMLSS) algorithm: an extension of the MLSS algorithm for the case of multiple discharges. The algorithm is tested using simulated scanning-EMG signals in different recording conditions, i.e., at different levels of muscle contraction and for different numbers of discharges per position. Results demonstrate that the algorithm eliminates artifacts more effectively than any previously available method and does so without distorting the waveform of the signal.
  • PublicationOpen Access
    A new muscle architecture model with non-uniform distribution of muscle fiber types
    (World Academy of Science, Engineering and Technology, 2007) Navallas Irujo, Javier; Malanda Trigueros, Armando; Gila Useros, Luis; Rodríguez Falces, Javier; Rodríguez Carreño, Ignacio; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa
    According to previous studies, some muscles present a non-homogeneous spatial distribution of its muscle fiber types and motor unit types. However, available muscle models only deal with muscles with homogeneous distributions. In this paper, a new architecture muscle model is proposed to permit the construction of non-uniform distributions of muscle fibers within the muscle cross section. The idea behind is the use of a motor unit placement algorithm that controls the spatial overlapping of the motor unit territories of each motor unit type. Results show the capabilities of the new algorithm to reproduce arbitrary muscle fiber type distributions.
  • PublicationOpen Access
    Validation of the filling factor index to study the filling process of the sEMG signal in the quadriceps
    (Elsevier, 2023) Rodríguez Falces, Javier; Malanda Trigueros, Armando; Mariscal Aguilar, Cristina; Niazi, Imran Khan; Navallas Irujo, Javier; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    Introduction: The EMG filling factor is an index to quantify the degree to which an EMG signal has been filled. Here, we tested the validity of such index to analyse the EMG filling process as contraction force was slowly increased. Methods: Surface EMG signals were recorded from the quadriceps muscles of healthy subjects as force was gradually increased from 0 to 40% MVC. The sEMG filling process was analyzed by measuring the EMG filling factor (calculated from the non-central moments of the rectified sEMG). Results: (1) As force was gradually increased, one or two prominent abrupt jumps in sEMG amplitude appeared between 0 and 10% of MVC force in all the vastus lateralis and medialis. (2) The jumps in amplitude were originated when a few large-amplitude MUPs, clearly standing out from previous activity, appeared in the sEMG signal. (3) Every time an abrupt jump in sEMG amplitude occurred, a new stage of sEMG filling was initiated. (4) The sEMG was almost completely filled at 2–12% MVC. (5) The filling factor decreased significantly upon the occurrence of an sEMG amplitude jump, and increased as additional MUPs were added to the sEMG signal. (6) The filling factor curve was highly repeatable across repetitions. Conclusions: It has been validated that the filling factor is a useful, reliable tool to analyse the sEMG filling process. As force was gradually increased in the vastus muscles, the sEMG filling process occurred in one or two stages due to the presence of abrupt jumps in sEMG amplitude.
  • PublicationOpen Access
    Motor unit action potential duration, II: a new automatic measurement method based on the wavelet transform
    (Lippincott, Williams & Wilkins, 2007) Rodríguez Carreño, Ignacio; Gila Useros, Luis; Malanda Trigueros, Armando; García Gurtubay, Ignacio; Mallor Giménez, Fermín; Gómez Elvira, Sagrario; Rodríguez Falces, Javier; Navallas Irujo, Javier; Ingeniería Eléctrica y Electrónica; Estadística e Investigación Operativa; Ingeniaritza Elektrikoa eta Elektronikoa; Estatistika eta Ikerketa Operatiboa
    To present and evaluate a new algorithm, based on the wavelet transform, for the automatic measurement of motor unit action potential (MUAP) duration. A total of 240 MUAPs were studied. The waveform of each MUAP was wavelet-transformed, and the start and end points were estimated by regarding the maxima and minima points in a particular scale of the wavelet transform. The results of the new method were compared with the gold standard of duration marker positions obtained by manual measurement. The new method was also compared with a conventional algorithm, which we had found to be best in a previous comparative study. To evaluate the new method against manual measurements, the dispersion of automatic and manual duration markers were analyzed in a set of 19 repeatedly recorded MUAPs. The differences between the new algorithm’s marker positions and the gold standard of duration marker positions were smaller than those observed with the conventional method. The dispersion of the new algorithm’s marker positions was slightly less than that of the manual one. Our new method for automatic measurement of MUAP duration is more accurate than other available algorithms and more consistent than manual measurements.
  • PublicationOpen Access
    Association of intrinsic capacity with respiratory disease mortality
    (Elsevier, 2023) Ramírez Vélez, Robinson; Iriarte-Fernández, María; Santafé Rodrigo, Guzmán; Malanda Trigueros, Armando; Beard, John R.; García Hermoso, Antonio; Izquierdo Redín, Mikel; Ciencias de la Salud; Estadística, Informática y Matemáticas; Ingeniería Eléctrica, Electrónica y de Comunicación; Institute for Advanced Materials and Mathematics - INAMAT2; Osasun Zientziak; Estatistika, Informatika eta Matematika; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    The World Health Organization (WHO) introduced a framework for healthy aging in 2015 that emphasizes functional ability instead of absence of disease. Healthy ageing is defined as “the process of building and maintaining the functional ability that enables well-being”. This framework considers an individual’s intrinsic capacity (IC), environment, and the interaction between them to determine functional ability. In this prospective cohort study, we investigated the link between mortality and various respiratory diseases in almost half a million adults who are part of the UK Biobank. We derived an IC score using measures from 4 of the 5 domains: two for psychological capacity, two for sensory capacity, two for vitality and one for locomotor capacity. The exposure variable in the study was the number of reported factors, which was summed and categorized into IC scores of zero, one, two, three, or at least four. The outcome was respiratory disease-related mortality, which was linked to national mortality records. The follow-up period started from participants’ inclusion in the UK Biobank study (2006–2010) and ended on December 31, 2021, or the participant’s death was censored. The average follow-up was 10.6 years (IQR 10.0; 11.3). During a median follow-up period of 10.6 years, 27,251 deaths were recorded. Out of these, 7.5% (2059) were primarily attributed to respiratory disease. The results showed that a higher IC score (+4 points) was associated with a significantly increased risk of respiratory disease mortality, with HRs of 3.34 [2.64 to 4.23] for men (C-index = 0.83) and 3.87 [2.86 to 5.23] for women (C-index = 0.84), independent of major confounding factors (P < 0.001). Our study provides evidence that lower levels of the WHO’s IC construct are associated with increased risk of mortality and various adverse health outcomes. The IC construct, which is easily and inexpensively measured, holds great promise for transforming geriatric care worldwide, including in regions without established geriatric medicine.