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Malanda Trigueros, Armando

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Malanda Trigueros

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Armando

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Ingeniería Eléctrica, Electrónica y de Comunicación

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ISC. Institute of Smart Cities

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0000-0002-3122-9049

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379

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Now showing 1 - 10 of 19
  • PublicationOpen Access
    Validation of the filling factor index to study the filling process of the sEMG signal in the quadriceps
    (Elsevier, 2023) Rodríguez Falces, Javier; Malanda Trigueros, Armando; Mariscal Aguilar, Cristina; Niazi, Imran Khan; Navallas Irujo, Javier; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    Introduction: The EMG filling factor is an index to quantify the degree to which an EMG signal has been filled. Here, we tested the validity of such index to analyse the EMG filling process as contraction force was slowly increased. Methods: Surface EMG signals were recorded from the quadriceps muscles of healthy subjects as force was gradually increased from 0 to 40% MVC. The sEMG filling process was analyzed by measuring the EMG filling factor (calculated from the non-central moments of the rectified sEMG). Results: (1) As force was gradually increased, one or two prominent abrupt jumps in sEMG amplitude appeared between 0 and 10% of MVC force in all the vastus lateralis and medialis. (2) The jumps in amplitude were originated when a few large-amplitude MUPs, clearly standing out from previous activity, appeared in the sEMG signal. (3) Every time an abrupt jump in sEMG amplitude occurred, a new stage of sEMG filling was initiated. (4) The sEMG was almost completely filled at 2–12% MVC. (5) The filling factor decreased significantly upon the occurrence of an sEMG amplitude jump, and increased as additional MUPs were added to the sEMG signal. (6) The filling factor curve was highly repeatable across repetitions. Conclusions: It has been validated that the filling factor is a useful, reliable tool to analyse the sEMG filling process. As force was gradually increased in the vastus muscles, the sEMG filling process occurred in one or two stages due to the presence of abrupt jumps in sEMG amplitude.
  • PublicationOpen Access
    EMG modeling
    (InTechOpen, 2012) Rodríguez Falces, Javier; Navallas Irujo, Javier; Malanda Trigueros, Armando; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa
    The aim of this chapter is to describe the approaches used for modelling electromyographic (EMG) signals as well as the principles of electrical conduction within the muscle. Sections are organized into a progressive, step-by-step EMG modeling of structures of increasing complexity. First, the basis of the electrical conduction that allows for the propagation of the EMG signals within the muscle is presented. Second, the models used for describing the electrical activity generated by a single fibre described. The third section is devoted to modeling the organization of the motor unit and the generation of motor unit potentials. Based on models of the architectural organization of motor units and their activation and firing mechanisms, the last section focuses on modeling the electrical activity of a complete muscle as recorded at the surface.
  • PublicationOpen Access
    Sliding window averaging in normal and pathological motor unit action potential trains
    (Elsevier, 2018) Malanda Trigueros, Armando; Navallas Irujo, Javier; Rodríguez Falces, Javier; Porta Cuéllar, Sonia; Fernández Martínez, Miguel; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    Objective: To evaluate the performance of a recently proposed motor unit action potential (MUAP) averaging method based on a sliding window, and compare it with relevant published methods in normal and pathological muscles. Methods: Three versions of the method (with different window lengths) were compared to three relevant published methods in terms of signal analysis-based merit figures and MUAP waveform parameters used in the clinical practice. 218 MUAP trains recorded from normal, myopathic, subacute neurogenic and chronic neurogenic muscles were analysed. Percentage scores of the cases in which the methods obtained the best performance or a performance not significantly worse than the best were computed. Results: For signal processing figures of merit, the three versions of the new method performed better (with scores of 100, 86.6 and 66.7%) than the other three methods (66.7, 25 and 0%, respectively). In terms of MUAP waveform parameters, the new method also performed better (100, 95.8 and 91.7%) than the other methods (83.3, 37.5 and 25%). Conclusions: For the types of normal and pathological muscle studied, the sliding window approach extracted more accurate and reliable MUAP curves than other existing methods. Significance: The new method can be of service in quantitative EMG.
  • PublicationOpen Access
    Motor unit action potential duration, I: variability of manual and automatic measurements
    (Lippincott, Williams & Wilkins, 2007) Rodríguez Carreño, Ignacio; Gila Useros, Luis; Malanda Trigueros, Armando; García Gurtubay, Ignacio; Mallor Giménez, Fermín; Gómez Elvira, Sagrario; Rodríguez Falces, Javier; Navallas Irujo, Javier; Ingeniería Eléctrica y Electrónica; Estadística e Investigación Operativa; Ingeniaritza Elektrikoa eta Elektronikoa; Estatistika eta Ikerketa Operatiboa
    To analyze the variability in manual measurements of motor unit action potential (MUAP) duration and to evaluate the effectiveness of well-known algorithms for automatic measurement. Two electromyographists carried out three independent duration measurements of a set of 240 MUAPs. The intraexaminer and interexaminer variabilities were analyzed by means of the Gage Reproducibility and Repeatability method. The mean of the three closest manually marked positions was considered the gold standard of the duration markers positions (GSP). The results of four wellknown automatic methods for estimating MUAP duration were compared with the GSP. Manual measurements of duration showed a lot of variability, with the combined intraoperator and interoperator variability greater than 30%. The greatest difference between manual positions was 11.2 ms. The mean differences between the GSP and those obtained with the four automatic methods ranged between 0.6 and 8.5 ms. Both manual and automatic measurements of MUAP duration show a high degree of variability. More precise methods are needed to improve the accuracy and reliability of the estimates of this parameter.
  • PublicationOpen Access
    Métodos de procesamiento y análisis de señales electromiográficas
    (Gobierno de Navarra, 2009) Gila Useros, Luis; Malanda Trigueros, Armando; Rodríguez Carreño, Ignacio; Rodríguez Falces, Javier; Navallas Irujo, Javier; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa
    La electromiografía clínica es una metodología de registro y análisis de la actividad bioeléctrica del músculo esquelético orientada al diagnóstico de las enfermedades neuromusculares. Las posibilidades de aplicación y el rendimiento diagnóstico de la electromiografía han evolucionado paralelamente al conocimiento de las propiedades de la energía eléctrica y al desarrollo de la tecnología eléctrica y electrónica. A mediados del siglo XX se introdujo el primer equipo comercial de electromiografía para uso médico basado en circuitos electrónicos analógicos. El desarrollo posterior de la tecnología digital ha permitido disponer de sistemas controlados por microprocesadores cada vez más fiables y potentes para captar, representar, almacenar, analizar y clasificar las señales mioeléctricas. Es esperable que el avance de las nuevas tecnologías de la información y la comunicación pueda conducir en un futuro próximo a la aplicación de desarrollos de inteligencia artificial que faciliten la clasificación automática de señales así como sistemas expertos de apoyo al diagnóstico electromiográfico.
  • PublicationOpen Access
    The filling factor of the sEMG signal at low contraction forces in the quadriceps muscles is influenced by the thickness of the subcutaneous layer
    (Frontiers Media, 2023) Rodríguez Falces, Javier; Malanda Trigueros, Armando; Mariscal Aguilar, Cristina; Navallas Irujo, Javier; Ingeniería Eléctrica, Electrónica y de Comunicación; Institute of Smart Cities - ISC; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    Introduction: It has been shown that, for male subjects, the sEMG activity at low contraction forces is normally 'pulsatile', i.e., formed by a few large-amplitude MUPs, coming from the most superficial motor units. The subcutaneous layer thickness, known to be greater in females than males, influences the electrode detection volume. Here, we investigated the influence of the subcutaneous layer thickness on the type of sEMG activity (pulsatile vs. continuous) at low contraction forces. Methods: Voluntary surface EMG signals were recorded from the quadriceps muscles of healthy males and females as force was gradually increased from 0% to 40% MVC. The sEMG filling process was examined by measuring the EMG filling factor, computed from the non-central moments of the rectified sEMG signal. Results: 1) The sEMG activity at low contraction forces was ¿continuous¿ in the VL, VM and RF of females, whereas this sEMG activity was ¿pulsatile¿ in the VL and VM of males. 2) The filling factor at low contraction forces was lower in males than females for the VL (p = 0.003) and VM (p = 0.002), but not for the RF (p = 0.54). 3) The subcutaneous layer was significantly thicker in females than males for the VL (p = 0.001), VM (p = 0.001), and RF (p = 0.003). 4) A significant correlation was found in the vastus muscles between the subcutaneous layer thickness and the filling factor (p < 0.05). Discussion: The present results indicate that the sEMG activity at low contraction forces in the female quadriceps muscles is 'continuous' due to the thick subcutaneous layer of these muscles, which impedes an accurate assessment of the sEMG filling process.
  • PublicationOpen Access
    M-wave changes caused by brief voluntary and stimulated isometric contractions
    (Springer, 2023) Rodríguez Falces, Javier; Malanda Trigueros, Armando; Navallas Irujo, Javier; Place, Nicolas; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
    Introduction Under isometric conditions, the increase in muscle force is accompanied by a reduction in the fbers’ length. The efects of muscle shortening on the compound muscle action potential (M wave) have so far been investigated only by computer simulation. This study was undertaken to assess experimentally the M-wave changes caused by brief voluntary and stimulated isometric contractions. Methods Two diferent methods of inducing muscle shortening under isometric condition were adopted: (1) applying a brief (1 s) tetanic contraction and (2) performing brief voluntary contractions of diferent intensities. In both methods, supramaximal stimulation was applied to the brachial plexus and femoral nerves to evoke M waves. In the frst method, electrical stimulation (20 Hz) was delivered with the muscle at rest, whereas in the second, stimulation was applied while participants performed 5-s stepwise isometric contractions at 10, 20, 30, 40, 50, 60, 70, and 100% MVC. The amplitude and duration of the frst and second M-wave phases were computed. Results The main fndings were: (1) on application of tetanic stimulation, the amplitude of the M-wave frst phase decreased (~10%, P<0.05), that of the second phase increased (~50%, P<0.05), and the M-wave duration decreased (~20%, P<0.05) across the frst fve M waves of the tetanic train and then plateaued for the subsequent responses; (2) when superimposing a single electrical stimulus on muscle contractions of increasing forces, the amplitude of the M-wave frst phase decreased (~20%, P<0.05), that of the second phase increased (~30%, P<0.05), and M-wave duration decreased (~30%, P<0.05) as force was raised from 0 to 60–70% MVC force. Conclusions The present results will help to identify the adjustments in the M-wave profle caused by muscle shortening and also contribute to diferentiate these adjustments from those caused by muscle fatigue and/or changes in Na+–K+ pump activity.
  • PublicationOpen Access
    EMG probability density function: a new way to look at EMG signal filling from single motor unit potential to full interference pattern
    (IEEE, 2023) Navallas Irujo, Javier; Eciolaza Ferrando, Adrián; Mariscal Aguilar, Cristina; Malanda Trigueros, Armando; Rodríguez Falces, Javier; Ingeniería Eléctrica, Electrónica y de Comunicación; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    An analytical derivation of the EMG signal's amplitude probability density function (EMG PDF) is presented and used to study how an EMG signal builds-up, or fills, as the degree of muscle contraction increases. The EMG PDF is found to change from a semi-degenerate distribution to a Laplacian-like distribution and finally to a Gaussian-like distribution. We present a measure, the EMG filling factor, to quantify the degree to which an EMG signal has been built-up. This factor is calculated from the ratio of two non-central moments of the rectified EMG signal. The curve of the EMG filling factor as a function of the mean rectified amplitude shows a progressive and mostly linear increase during early recruitment, and saturation is observed when the EMG signal distribution becomes approximately Gaussian. Having presented the analytical tools used to derive the EMG PDF, we demonstrate the usefulness of the EMG filling factor and curve in studies with both simulated signals and real signals obtained from the tibialis anterior muscle of 10 subjects. Both simulated and real EMG filling curves start within the 0.2 to 0.35 range and rapidly rise towards 0.5 (Laplacian) before stabilizing at around 0.637 (Gaussian). Filling curves for the real signals consistently followed this pattern (100% repeatability within trials in 100% of the subjects). The theory of EMG signal filling derived in this work provides (a) an analytically consistent derivation of the EMG PDF as a function of motor unit potentials and motor unit firing patterns; (b) an explanation of the change in the EMG PDF according to degree of muscle contraction; and (c) a way (the EMG filling factor) to quantify the degree to which an EMG signal has been built-up.
  • PublicationOpen Access
    Independent component analysis as a tool to eliminate artifacts in EEG. A quantitative study
    (Lippincott, Williams & Wilkins, 2003) Iriarte, Jorge; Urrestarazu, Elena; Valencia Ustárroz, Miguel; Alegre, Manuel; Malanda Trigueros, Armando; Viteri, César; Artieda, Julio; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa
    Independent component analysis (ICA) is a novel technique that calculates independent components from mixed signals. A hypothetical clinical application is to remove artifacts in EEG. The goal of this study was to apply ICA to standard EEG recordings to eliminate well-known artifacts, thus quantifying its efficacy in an objective way. Eighty samples of recordings with spikes and evident artifacts of electrocardiogram (EKG), eye movements, 50-Hz interference, muscle, or electrode artifact were studied. ICA components were calculated using the Joint Approximate Diagonalization of Eigen-matrices (JADE) algorithm. The signal was reconstructed excluding those components related to the artifacts. A normalized correlation coefficient was used as a measure of the changes caused by the suppression of these components. ICA produced an evident clearing-up of signals in all the samples. The morphology and the topography of the spike were very similar before and after the removal of the artifacts. The correlation coefficient showed that the rest of the signal did not change significantly. Two examiners independently looked at the samples to identify the changes in the morphology and location of the discharge and the artifacts. In conclusion, ICA proved to be a useful tool to clean artifacts in short EEG samples, without having the disadvantages associated with the digital filters. The distortion of the interictal activity measured by correlation analysis was minimal.
  • PublicationOpen Access
    Association of intrinsic capacity with respiratory disease mortality
    (Elsevier, 2023) Ramírez Vélez, Robinson; Iriarte-Fernández, María; Santafé Rodrigo, Guzmán; Malanda Trigueros, Armando; Beard, John R.; García Hermoso, Antonio; Izquierdo Redín, Mikel; Ciencias de la Salud; Estadística, Informática y Matemáticas; Ingeniería Eléctrica, Electrónica y de Comunicación; Institute for Advanced Materials and Mathematics - INAMAT2; Osasun Zientziak; Estatistika, Informatika eta Matematika; Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren
    The World Health Organization (WHO) introduced a framework for healthy aging in 2015 that emphasizes functional ability instead of absence of disease. Healthy ageing is defined as “the process of building and maintaining the functional ability that enables well-being”. This framework considers an individual’s intrinsic capacity (IC), environment, and the interaction between them to determine functional ability. In this prospective cohort study, we investigated the link between mortality and various respiratory diseases in almost half a million adults who are part of the UK Biobank. We derived an IC score using measures from 4 of the 5 domains: two for psychological capacity, two for sensory capacity, two for vitality and one for locomotor capacity. The exposure variable in the study was the number of reported factors, which was summed and categorized into IC scores of zero, one, two, three, or at least four. The outcome was respiratory disease-related mortality, which was linked to national mortality records. The follow-up period started from participants’ inclusion in the UK Biobank study (2006–2010) and ended on December 31, 2021, or the participant’s death was censored. The average follow-up was 10.6 years (IQR 10.0; 11.3). During a median follow-up period of 10.6 years, 27,251 deaths were recorded. Out of these, 7.5% (2059) were primarily attributed to respiratory disease. The results showed that a higher IC score (+4 points) was associated with a significantly increased risk of respiratory disease mortality, with HRs of 3.34 [2.64 to 4.23] for men (C-index = 0.83) and 3.87 [2.86 to 5.23] for women (C-index = 0.84), independent of major confounding factors (P < 0.001). Our study provides evidence that lower levels of the WHO’s IC construct are associated with increased risk of mortality and various adverse health outcomes. The IC construct, which is easily and inexpensively measured, holds great promise for transforming geriatric care worldwide, including in regions without established geriatric medicine.