Lusa Cadore, Eduardo

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Lusa Cadore

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Eduardo

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Ciencias de la Salud

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Now showing 1 - 5 of 5
  • PublicationOpen Access
    Strength and endurance training prescription in healthy and frail elderly
    (International Society on Aging and Disease (ISOAD), 2014) Lusa Cadore, Eduardo; Pinto, Ronei Silveira; Bottaro, Martim; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak
    Aging is associated with declines in the neuromuscular and cardiovascular systems, resulting in an impaired capacity to perform daily activities. Frailty is an age-associated biological syndrome characterized by decreases in the biological functional reserve and resistance to stressors due to changes in several physiological systems, which puts older individuals at special risk of disability. To counteract the neuromuscular and cardiovascular declines associated with aging, as well as to prevent and treat the frailty syndrome, the strength and endurance training seems to be an effective strategy to improve muscle hypertrophy, strength and power output, as well as endurance performance. The first purpose of this review was discuss the neuromuscular adaptations to strength training, as well as the cardiovascular adaptations to endurance training in healthy and frail elderly subjects. In addition, the second purpose of this study was investigate the concurrent training adaptations in the elderly. Based on the results found, the combination of strength and endurance training (i.e., concurrent training) performed at moderate volume and moderate to high intensity in elderly populations is the most effective way to improve both neuromuscular and cardiorespiratory functions. Moreover, exercise interventions that include muscle power training should be prescribed to frail elderly in order to improve the overall physical status of this population and prevent disability.
  • PublicationOpen Access
    Effects of multicomponent exercise training on the intrinsic capacity in frail older adults: review of clinical trials
    (Universidade Estadual Paulista, 2022) Mello, Alexandre; Izquierdo Redín, Mikel; Teodoro, Juliana Lopes; Lusa Cadore, Eduardo; Ciencias de la Salud; Osasun Zientziak
    Aim: To review the effects of multicomponent exercise training on the domains of the intrinsic capacity of physically frail older adults: locomotion, vitality, cognition, psychological outcomes, and sensory function. Methods: The search for the studies was carried out in the MEDLINE, Cochrane CENTRAL, and PEDro databases, along with manual search, delimiting the period of publication as the last 10 years. The initial search identified 338 studies and 18 among them were analyzed qualitatively. Results: From the analysis of the included studies, great variability was evidenced between the intervention protocols, as well as between the results. As for the effectiveness of multicomponent exercise training, it has been shown to induce a positive effect on most of the analyzed outcomes. Conclusion: In summary, the present review suggests that multicomponent physical training can be effective to improve aspects of locomotion, cognition, and psychological aspects in frail older populations. Nevertheless, more studies are needed to specify the time needed to achieve such adaptations, the magnitude of these adaptations, and the design of the most appropriate training program for each outcome related to intrinsic capabilities.
  • PublicationOpen Access
    Noncoronary vascular calcification, bone mineral density, and muscle mass in institutionalized frail nonagenarians
    (Mary Ann Liebert, 2017-08-01) Idoate, Fernando; Lusa Cadore, Eduardo; Casas Herrero, Álvaro; Zambom Ferraresi, Fabrício; Martínez Velilla, Nicolás; Rodríguez Mañas, Leocadio; Azcárate, Pedro M.; Bottaro, Martim; Ramírez Vélez, Robinson; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak
    The purpose of this study was to compare the vascular calcification in thoracic aorta (TAC), abdominal aorta (AAC), iliac arteries (IAC), and femoral arteries (FAC) and bone mineral density (BMD) of the lumbar vertebrae between frail and robust nonagenarians, as well as to verify the associations between vascular calcification with BMD, muscle tissue quality, and quantity in both groups. Forty-two elderly subjects participated in this study: 29 institutionalized frail (92.0 ± 3.2 years) and 13 robust (89.0 ± 4.0 years) elderly participants. All patients underwent nonenhanced helical thoracic, abdominal, and thigh computed tomography. The frail group presented significantly greater FAC as well as less lumbar BMD than the robust group (p < 0.05). In the frail group, significant negative relationships were observed between the individual values of FAC with the individual values of BMD (r = −0.35 to −0.43, p < 0.05) and with the individual values of the quadriceps muscle quantity and quality (r = −0.52, p < 0.01), whereas no significant relationships were observed in the robust group. The robust group presented less vascular calcification and more BMD in the vertebral bodies than the frail group. In the frail group, femoral artery calcification was significantly negatively correlated with BMD, leg muscle quality, and muscle mass volume.
  • PublicationOpen Access
    Inter-individual variability in response to exercise intervention or usual care in hospitalized older adults
    (Wiley, 2019) López Sáez de Asteasu, Mikel; Martínez Velilla, Nicolás; Zambom Ferraresi, Fabrício; Casas Herrero, Álvaro; Lusa Cadore, Eduardo; Ramírez Vélez, Robinson; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak; Gobierno de Navarra / Nafarroako Gobernua, 2186/2014
    Background: Exercise protocols applied during hospitalization can prevent functional and cognitive decline in older adults. The purpose of this study was to examine the individual response of acutely hospitalized patients to usual care and to physical exercise on functional capacity, muscle strength, and cognitive function and to assess the relationship with mortality at 1 year post-discharge. Methods: In a single-blind randomized clinical trial, 370 hospitalized patients [56.5% women; mean age (standard deviation) 87.3 (4.9) years] were allocated to an exercise intervention group (IG, n = 185) or a control group (CG, n = 185). The participants were older adults aged 75 years or older in an acute care unit in a tertiary public hospital in Navarra, Spain. The usual care group received habitual hospital care, which included physical rehabilitation when needed. The in-hospital intervention included individualized multicomponent exercise training programme performed during 5–7 consecutive days (two sessions/day). Functional capacity was assessed with the Short Physical Performance Battery (SPPB) test and the Gait Velocity Test (GVT). Handgrip strength and cognitive function were also measured at admission and discharge. Patients in both groups were categorized as responders (Rs), non-responders (NRs), and adverse responders (ARs) based on the individual response to each treatment during hospitalization. Results: The prevalence of Rs was higher and the prevalence of NRs and ARs was lower in the intervention group than in the control group for functional capacity (SPPB IG: Rs 85.3%, NRs 8.7%, ARs 6.0% vs. CG: Rs 37.9%, NRs 28.8%, ARs 33.3% and GVT IG: Rs 51.2%, NRs 47.3, ARs 1.6% vs. CG: Rs 18.0%, NRs 67.7%, ARs 14.3%), muscle strength (IG: Rs 62.3%, NRs 26.5%, ARs 11.3% vs. CG: Rs 20.0%, NRs 38.0%, ARs 42.0%), and cognition (IG: Rs 41.5%, NRs 57.1%, ARs 1.4% vs. CG: Rs 13.8%, NRs 76.6%, ARs 9.7%) (all P < 0.001). The ARs for the GVT in the control group and the ARs for the SPPB in the intervention group had a significantly higher rate of mortality than the NRs and Rs in the equivalent groups (0.01 and 0.03, respectively) at follow-up. Conclusions: Older patients performing an individualized exercise intervention presented higher prevalence of Rs and a lower prevalence of NRs and ARs for functional capacity, muscle strength, and cognitive function than those who were treated with usual care during acute hospitalization. An adverse response on functional capacity in older patients to physical exercise or usual care during hospitalization was associated with mortality at 1 year post-discharge.
  • PublicationOpen Access
    Ejercicio físico en el anciano frágil: una manera eficaz de prevenir la dependencia
    (Universidad Europea de Madrid, 2014) Izquierdo Redín, Mikel; Lusa Cadore, Eduardo; Casas Herrero, Álvaro; Ciencias de la Salud; Osasun Zientziak
    Los beneficios del ejercicio físico en el envejecimiento y, específicamente, en la fragilidad han sido objeto de reciente investigación científica. En el anciano, la práctica de actividad física regular se asocia a una disminución del riesgo de mortalidad, de enfermedades crónicas, institucionalización, deterioro cognitivo y funcional. La práctica de ejercicio físico es la intervención más eficaz para retrasar la discapacidad y los eventos adversos que asocia habitualmente el síndrome de la fragilidad. De manera más concreta, el tipo de ejercicio físico más beneficioso en el anciano frágil es el denominado “entrenamiento multicomponente”. Este tipo de programas combina entrenamiento de fuerza, resistencia, equilibrio y marcha, y es con el que más mejorías se ha demostrado en la capacidad funcional, que es un elemento fundamental para el mantenimiento de la independencia en las actividades básicas de la vida diaria (ABVD) de los ancianos. Los objetivos deberían centrarse, por tanto, en mejorar dicha capacidad funcional a través de mejorías en el equilibrio y la marcha, así como mediante la disminución del riesgo y del número de caídas. Para la obtención de estos objetivos, el diseño de un programa de ejercicio físico en el anciano frágil debe acompañarse necesariamente de recomendaciones sobre variables tales como la intensidad, la potencia, el volumen y la frecuencia de entrenamiento ideales en esta población.