(American Chemical Society, 2020) Lafuente Adiego, Marta; Pellejero, Ismael; Clemente, Alberto; Urbiztondo, Miguel A.; Mallada, Reyes; Reinoso, Santiago; Pina, María del Pilar; Gandía Pascual, Luis; Institute for Advanced Materials and Mathematics - INAMAT2; Gobierno de Navarra / Nafarroako Gobernua; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
We present a simple, versatile and low-cost approach for the preparation of
SERS-active regions within a microfluidic channel 50 cm in length. The approach involves the
UV-light-driven formation of polyoxometalate-decorated gold nanostructures, Au@POM (POM:
H3PW12O40 (PW) and H3PMo12O40 (PMo)), that self-assemble in situ on the surface of the
PDMS microchannels without any extra functionalization procedure. The fabricated LoCs were
characterized by SEM, UV-Vis, Raman, XRD and XPS techniques. The SERS activity of the
resulting Au@POM–coated lab-on-a-chip (LoC) devices was evaluated in both static and flow
conditions using Rhodamine R6G. The SERS response of Au@PW–based LoCs was found
superior to Au@PMo counterparts and outstanding when compared to reported data on
metal@POM nanocomposites. We demonstrate the potentialities of both Au@POM–coated
LoCs as analytical platforms for real time detection of the organophosphorous pesticide
Paraoxon-methyl at 10-6 M concentration level.
