Open Access
Effects of exercise interventions on inflammatory parameters in acutely hospitalized older patients: a systematic review and meta-analysis of randomized controlled trials
(MDPI, 2021) Ramírez Vélez, Robinson; García Hermoso, Antonio; Martínez Velilla, Nicolás; Zambom Ferraresi, Fabrício; López Sáez de Asteasu, Mikel; Recarey Rodríguez, Anel Eduardo; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa; Gobierno de Navarra / Nafarroako Gobernua
The purpose of this systematic review and meta-analysis was to appraise the acute effects of exercise training on inflammatory parameters in hospitalized older adults. We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Web of Science, Medline and PubMed were searched for studies published until August 2020. The review included all randomized controlled trials (RCTs) that evaluated and compared the effect of exercise versus usual care on inflammatory parameters in acutely hospitalized older adults. Two reviewers independently assessed the studies. The quality of all the included studies was assessed using the DerSimonian–Laird random-effects inverse-variance model. Five studies (275 participants) met the inclusion criteria. The exercise interventions included resistance or multicomponent intervention programs. The results indicate that, compared with usual care, exercise interventions have a positive impact on overall inflammatory parameters, including C-reactive protein (CRP) and insulin-like growth factor-I (IGF-1) (Hedge's g = −0.19, 95% confidence interval [CI] −0.33 to −0.04, p = 0.011, I2 = 0%). However, analyses of individual inflammatory parameters revealed a non-significant trend for reductions in CRP (Hedge's g = −0.20, 95% CI −0.47 to 0.07, p = 0.151, I2 = 31.2%) and IGF-I (Hedge's g = −0.34, 95% CI −0.79 to 0.11, p = 0.138, I2 = 0%). On the basis of this review, we conclude that exercise during acute hospitalization offers a mild improvement in the inflammatory profile over usual care in older patients. Nevertheless, due to limited number of RCTs, our findings must be interpreted with caution and confirmed in future studies.
Open Access
Efectos de realizar actividad física en la función muscular en EPOC
(Universidad Autonoma de Madrid y Comunidad Virtual Ciencias del Deporte, 2021) Cebollero Rivas, Pilar; Zambom Ferraresi, Fabrício; Hueto, Javier; Cascante Rodrigo, José Antonio; Antón Olóriz, María Milagros; Ciencias de la Salud; Osasun Zientziak
El objetivo de este estudio fue examinar los efectos de un programa de actividad física (AF) de andar en la función muscular en pacientes con EPOC (Enfermedad Pulmonar Obstructiva Crónica), con un seguimiento de 12 meses. Se reclutaron 44 hombres (70,3 ± 6,7 años) diagnosticados de EPOC moderado-severo. El grupo intervención realizó un programa de actividad física (GAF) y el grupo control (GCO) siguió su tratamiento estándar. Se midió la fuerza máxima (1RM) del miembro inferior y superior, la potencia muscular del miembro inferior (50% y 70% 1RM) y la actividad física, antes y después de 12 meses. A los 12 meses, incremento un 8% (P<0,01) la 1RM del miembro inferior en GAF, sin cambios en GCO. La potencia muscular al 50%1RM incrementó un 12% en GAF, disminuyendo un 9% in GCO (P<0,05). Un programa de AF incrementa la fuerza y preserva la potencia muscular del miembro inferior.
Open Access
Role of physical exercise on cognitive function in healthy older adults: a systematic review of randomized clinical trials
(Elsevier, 2017-08-01) López Sáez de Asteasu, Mikel; Zambom Ferraresi, Fabrício; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak
Cognitive impairment has a harmful effect on quality of life, is associated with functional limitations and disability in older adults. Physical activity (PA) has shown to have beneficial effects on cognition but the results and conclusions of randomized controlled trials (RCTs) are less consistent. Update of knowledge was necessary to examine the effects on cognitive function of new training modalities developed in recent years, such as multicomponent exercise training. Therefore, the purpose of this review was to examine the role of multicomponent training versus aerobic or resistance training alone on cognition in healthy older adults (>65 years) without known cognitive impairment. The mean differences (MD) of the parameters from pre-intervention to post-intervention between groups were pooled using a random-effects model. Twenty-one RCTs published between 2002 and 2016 were included. Multicomponent exercise training may have the most positive effects on cognitive function in older adults. The small number of included studies and the large variability in study populations, study design, exercise protocols, adherence rates and outcome measures complicate the interpretation of the results and contribute to discrepancies within the exercise research literature.

Zambom Ferraresi, Fabrício

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