Labayen Goñi, Idoia
Loading...
Email Address
person.page.identifierURI
Birth Date
Job Title
Last Name
Labayen Goñi
First Name
Idoia
person.page.departamento
Ciencias de la Salud
person.page.instituteName
IS-FOOD. Research Institute on Innovation & Sustainable Development in Food Chain
ORCID
person.page.observainves
person.page.upna
Name
- Publications
- item.page.relationships.isAdvisorOfPublication
- item.page.relationships.isAdvisorTFEOfPublication
- item.page.relationships.isAuthorMDOfPublication
2 results
Search Results
Now showing 1 - 2 of 2
Publication Open Access Interaction effect of the Mediterranean diet and an obesity genetic risk score on adiposity and metabolic syndrome in adolescents: the HELENA study(MDPI, 2020) Seral-Cortes, Miguel; Sabroso-Lasa, Sergio; Miguel Etayo, Carmen de; González Gross, Marcela; Gesteiro, Eva; Molina Hidalgo, Cristina; Henauw, Stefaan de; Erhardt, Éva; Manios, Yannis; Karaglani, Eva; Widhalm, Kurt; Kafatos, Antonios; Béghin, Laurent; Meirhaeghe, Aline; Salazar-Tortosa, Diego; Ruiz, Jonatan R.; Moreno, Luis A.; Esteban, Luis Mariano; Labayen Goñi, Idoia; Ciencias de la Salud; Osasun ZientziakObesity and metabolic syndrome (MetS) are worldwide major health challenges. The Mediterranean diet (MD) is associated with a better cardiometabolic profile, but these beneficial effects may be influenced by genetic variations, modulating the predisposition to obesity or MetS. The aim was to assess whether interaction effects occur between an obesity genetic risk score (obesity-GRS) and the MD on adiposity and MetS in European adolescents. Multiple linear regression models were used to assess the interaction effects of an obesity-GRS and the MD on adiposity and MetS and its components. Interaction effects between the MD on adiposity and MetS were observed in both sex groups (p < 0.05). However, those interaction effects were only expressed in a certain number of adolescents, when a limited number of risk alleles were present. Regarding adiposity, a total of 51.1% males and 98.7% females had lower body mass index (BMI) as a result of higher MD adherence. Concerning MetS, only 9.9% of males with higher MD adherence had lower MetS scores. However, the same effect was observed in 95.2% of females. In conclusion, obesity-related genotypes could modulate the relationship between MD adherence and adiposity and MetS in European adolescents; the interaction effect was higher in females than in males.Publication Open Access Interplay of the mediterranean diet and genetic hypertension risk on blood pressure in european adolescents: findings from the HELENA study(Springer, 2024) Pérez-Gimeno, Gloria; Seral-Cortes, Miguel; Sabroso-Lasa, Sergio; Esteban, Luis Mariano; Widhalm, Kurt; Gottrand, Frédéric; Stehle, Peter; Meirhaeghe, Aline; Muntaner, Manon; Kafatos, Antonios; Gutiérrez, Ángel; Manios, Yannis; Anastasiou, Costas A.; González Gross, Marcela; Breidenassel, Christina; Censi, Laura; Henauw, Stefaan de; Labayen Goñi, Idoia; Bueno-Lozano, Gloria; Rupérez, Azahara I.; Moreno, Luis A.; Ciencias de la Salud; Osasun Zientziak; Institute on Innovation and Sustainable Development in Food Chain - ISFOODEarly-life onset of high blood pressure is associated with the development of cardiovascular diseases in adulthood. In adolescents, limited evidence exists regarding the association between adherence to the Mediterranean Diet (MedDiet) and normal blood pressure (BP) levels, as well as its potential to modulate genetic predisposition to HTN. This study investigated the interaction between a MedDiet score and a recently developed HTN-genetic risk score (HTN-GRS) on blood pressure levels in a European adolescent cohort. The MedDiet score was derived from two non-consecutive 24-h dietary recalls and ranged from 0 (indicating low adherence) to 9 (indicating high adherence). Multiple linear regression models, adjusted for covariates, were employed to examine the relationship between the MedDiet score and BP z-scores and to assess the interaction effects between the MedDiet score and HTN-GRS on BP z-scores. MedDiet score showed a negative association with z-systolic BP (SBP) (ß = -0.40, p < 0.001) and z-diastolic BP (DBP) (ß = -0.29, p = 0.001). Additionally, a significant interaction effect was identified between the MedDiet score and HTN-GRS on z-SBP (ß = 0.02, p < 0.001) and z-DBP (ß = 0.02, p < 0.001). The modulatory effect of the MedDiet was more pronounced in females than in males, and HTN-GRS exhibited a stronger influence on DBP than on SBP. Conclusion: The study suggests that higher adherence to the MedDiet is associated with reduced BP levels in adolescents and provides evidence of a genetic-diet interaction influencing BP in adolescents. (Table presented.)