Matías Maestro, Ignacio

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https://academica-e.unavarra.es/handle/2454/49553

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Matías Maestro

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Ignacio

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Ingeniería Eléctrica, Electrónica y de Comunicación

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ISC. Institute of Smart Cities

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0000-0002-2229-6178

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88510

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1896

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Author: Matías Maestro, Ignacio × Subject: Immunosensors ×

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    PublicationOpen Access
    Fiber-optic immunosensor based on lossy mode resonances induced by indium tin oxide thin-films
    (IEEE, 2017) Socorro Leránoz, Abián Bentor; Del Villar, Ignacio; Corres Sanz, Jesús María; Arregui San Martín, Francisco Javier; Matías Maestro, Ignacio; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa; Institute of Smart Cities - ISC
    A novel immunosensor based on lossy mode resonances (LMRs) induced in optical fibers is developed in this contribution. Indium tin oxide (ITO) is sputtered on the optical substrate to generate an LMR in the transmission spectrum. Type G immunoglobulins (IgGs) are then attached to the ITO-coated fiber using (3-glycidyloxypropyl)trimethoxysilane (GPTMS). A phosphate buffer saline solution containing anti-IgGs is used to detect the biological reactions. The presented device is capable of detecting anti-IgG concentrations up to 10 nM. These results will permit the fabrication of biosensors based on a covalent attachment of bioreceptors over an LMR inducing thin-film.