Matías Maestro, Ignacio
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Matías Maestro
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Ignacio
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Ingeniería Eléctrica, Electrónica y de Comunicación
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ISC. Institute of Smart Cities
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Publication Open Access SnO2 based optical fiber refractometers(SPIE, 2012) Sánchez Zábal, Pedro; Ruiz Zamarreño, Carlos; Hernáez Sáenz de Zaitigui, Miguel; Del Villar, Ignacio; Matías Maestro, Ignacio; Arregui San Martín, Francisco Javier; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa; Gobierno de Navarra / Nafarroako GobernuaIn this work, the fabrication and characterization of refractometers based on lossy mode resonances (LMR) is presented. Tin dioxide (SnO2) films deposited on optical fibers are used as the LMR supporting coatings. These resonances shift to the red as a function of the external refractive index, enabling the fabrication of robust and highly reproducible wavelength-based optical fiber refractometers. The obtained SnO2-based refractometer shows an average sensitivity of 7198 nm/refractive index unit (RIU) in the range 1.333-1.420 RIU.Publication Open Access High sensitive and selective C-reactive protein detection by means of lossy mode resonance based optical fiber devices(Elsevier, 2017) Zubiate Orzanco, Pablo; Ruiz Zamarreño, Carlos; Sánchez Zábal, Pedro; Matías Maestro, Ignacio; Arregui San Martín, Francisco Javier; Institute of Smart Cities - ISC; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa; Universidad Pública de Navarra / Nafarroako Unibertsitate PublikoaThis work presents the development of high sensitive, selective, fast and reusable C-reactive protein (CRP) aptasensors. This novel approach takes advantage of the utilization of high sensitive refractometers based on Lossy Mode Resonances generated by thin indium tin oxide (ITO) films fabricated onto the planar region of D-shaped optical fibers. CRP selectivity is obtained by means of the adhesion of a CRP specific aptamer chain onto the ITO film using the Layer-by-Layer (LbL) nano-assembly fabrication process. The sensing mechanism relies on resonance wavelength shifts originated by refractive index variations of the aptamer chain in presence of the target molecule. Fabricated devices show high selectivity to CRP when compared with other target molecules, such as urea or creatinine, while maintaining a low detection limit (0.0625 mg/L) and fast response time (61 s). Additionally, these sensors show a repetitive response for several days and are reusable after a cleaning process in ultrapure water.Publication Open Access Fiber-optic lossy mode resonance sensors(Elsevier, 2014) Arregui San Martín, Francisco Javier; Del Villar, Ignacio; Corres Sanz, Jesús María; Goicoechea Fernández, Javier; Ruiz Zamarreño, Carlos; Elosúa Aguado, César; Hernáez Sáenz de Zaitigui, Miguel; Rivero Fuente, Pedro J.; Socorro Leránoz, Abián Bentor; Urrutia Azcona, Aitor; Sánchez Zábal, Pedro; Zubiate Orzanco, Pablo; López Torres, Diego; Acha Morrás, Nerea de; Matías Maestro, Ignacio; Ingeniería Eléctrica y Electrónica; Ingeniaritza Elektrikoa eta Elektronikoa; Gobierno de Navarra / Nafarroako GobernuaIn the last 4 years, experimental evidences about the potential use of optical sensors based on Lossy Mode Resonances (LMR) have been presented in the literature. These LMR sensors have some similarities with Surface Plasmon Resonance (SPR) sensors, the gold standard in label-free, real-time biomolecular interaction analysis. In these new LMR sensors, if the non-metallic nanocladding of an optical waveguide fulfills the conditions explained in this work, coupling of light to the cladding modes happens at certain resonance wavelengths, which enables the use of LMR devices as refractometers and opens the door to diverse applications such as in biology and proteomics research. These highly sensitive refractometers have already shown sensitivities higher than 20,000 nm/RIU or 5x10-7 RIU and, given the youth of this field, it is expected to achieve even better values.