Rivera, Diego
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Rivera
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Diego
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Ciencias de la Salud
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Publication Open Access Multivariate base rates of low score on neuropsychological tests of individuals with coca paste use disorder(Oxford University Press, 2023) Vergara Moragues, Esperanza; Acosta Barreto, María Rocío; Rivera, Diego; Santiago Ramajo, Sandra; González-Saiz, Francisco; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakOBJECTIVE: The aim of this study was to determine the prevalence of low scores on eight commonly used neuropsychological tests to evaluate learning and memory, language, and executive functions in individuals with coca paste use disorders (CPUD) and to identify the differences with respect to a group of healthy nonconsuming subjects (HCs). METHODS: 162 Colombian adults with CPUD and a group of 162 Colombian adult HCs participated in this comparative study. Eight tests (eighteen test scores) were grouped into three categories: learning and memory, language, and executive functions. Each participant was categorized based on the number of low scoring tests in specific percentile cut-off groups (25th, 16th, 10th, 5th, and 2nd). RESULTS: In the learning and memory domain, 89.5% of individuals with CPUD and 55.6% of HCs scored below the 25th percentile on at least one of the five test scores, in the language domain, 80.7% of individuals with CPUD and 58% of HCs and in the executive function domain, 92% of individuals with CPUD and 67.3% of HCs. Having two or more scores below the 10th percentile or 10 or more at the 5th percentile shows an optimal cut-off for determining the sensitivity and specificity for discriminating between the two groups. CONCLUSIONS: The individuals with CPUD had a higher percentage of low scores than the HCs in the domains of learning and memory, language, and executive function. It is important for clinicians to be aware of low scores in individuals with CPUD to avoid false-positive diagnoses of cognitive impairment.Publication Open Access Neuropsychological functioning of individuals with coca paste use disorder(Taylor & Francis, 2020) Vergara Moragues, Esperanza; Acosta Barreto, María Rocío; Santiago Ramajo, Sandra; Rivera, Diego; Pardo Pachón, Jennifer Alexandra; Ciencias de la Salud; Osasun ZientziakBackground: Cocaine use has increased worldwide in recent years. However, the specific effects of smoking coca paste and its consequences on the cognitive functioning of individuals are unknown. The purposes of this study were to compare the neuropsychological functioning of a group of 163 individuals with coca-paste use disorder (CPUD) to that of a group of 162 healthy controls (HC) and to examine the relationship between cognitive performance and sociodemographic characteristics of these groups. Methods: Participants were administered a comprehensive neuropsychological battery that included tests of learning and memory, language and executive functions. Results: Although there were no significant differences in age and educational level between the groups, individuals with CPUD had significantly lower cognitive performance on the tests of learning and memory, language and executive functions compared with HC. An interaction effect was observed between group (CPUD versus HC) and educational level in the cognitive domains of learning and memory and language, such that more years of education was associated with better performance in these domains only in the HC. Conclusions: Deficits in learning and memory, language and executive functions are common in individuals with CPUD. Cognitive rehabilitation programs have been shown to improve these functions in individuals with CPUD. Therefore, this study reinforces the necessity of including such programs as part of the holistic intervention plan for these individuals.