Open Access
Tracking of physical fitness levels from childhood and adolescence to adulthood: a systematic review and meta-analysis
(AME Publishing, 2022) García Hermoso, Antonio; Izquierdo Redín, Mikel; Ramírez Vélez, Robinson; Ciencias de la Salud; Osasun Zientziak
Background: prospective and large studies indicate that high physical fitness levels during young are beneficial for health during adulthood. The aim of the study was to investigate the tracking of physical fitness components from childhood and/or adolescence to adulthood. Methods: two authors systematically searched MEDLINE and Web of Science electronic databases for relevant articles. Studies with apparently healthy youth aged 6-18 years who track their physical fitness to adulthood were included. Our study carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Correlation coefficients (r) were used as effect size. Random-effects models were used to estimate the pooled effect size. Correlation coefficients were interpreted as follows: <0.30 low stability, 0.30 to 0.60 moderate stability, and >0.60 high stability. Risk of bias of each study was determined by The Quality Assessment Tool for Observational Cohort and Cross-sectional Studies. Results: twenty-one prospective studies were included in the meta-analysis (n=6,197 participants at follow-up, 47.4% women). The mean length of follow-up was 20.8 years. Overall, cardiorespiratory fitness (r=0.38; 95% CI: 0.29-0.48; I2=92.7%), muscular strength (r=0.51; 95% CI: 0.43-0.59; I2=87.9%), and muscular endurance (r=0.50; 95% CI: 0.36-0.86; I2=94.5%) show moderate tracking from childhood and/or adolescence to adulthood, independent of test used and length of follow-up. This moderate tracking was slightly stronger in women than in men and from adolescence compared to childhood. Trunk flexibility component, assessed with the sit and reach test, exhibits high stability (r=0.69; 95% CI: 0.58-0.81; I2=92.9%). Interestingly, meta-regression analysis shows positive association between correlation coefficient for flexibility and the length of follow-up (β =0.017; 95% CI: 0.012-0.021). Discussion: although the current study found inconsistency between results, the findings suggest that acquiring high physical fitness levels should be targeted already from childhood and adolescence given that low levels of fitness in adulthood are related with several chronic diseases and mortality.
Open Access
Association of muscular fitness and body fatness with cardiometabolic risk factors: the FUPRECOL study
(MDPI, 2018) Correa Rodríguez, María; Ramírez Vélez, Robinson; Correa Bautista, Jorge Enrique; Castellanos-Vega, Rocío del Pilar; Arias-Coronel, Florencio; González Ruiz, Katherine; Carrillo Arango, Hugo Alejandro; Schmidt Río-Valle, Jacqueline; González Jiménez, Emilio; Ciencias de la Salud; Osasun Zientziak
This study investigated the associations of muscular fitness and various indicators of body fatness with cardio-metabolic risk factors and determined the muscular strength and body fatness thresholds for detecting a high risk of cardio-metabolic dysfunction in young adults. A cross-sectional study was conducted on 1798 collegiate students (61.5% females, mean age 20.5 years). Muscular fitness was determined by using a handgrip strength test and normalized grip strength (NGS = handgrip (kg)/body mass (kg)). Body mass index (BMI), waist circumference (WC), percentage of fat mass (BF%), fat-mass index (FMI), and waist-to-height ratio (WHR) were also included as body fatness measurements. A high cardio-metabolic risk cluster was derived by assessing triglycerides, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, fasting glucose, and blood pressure. Logistic regression models showed that men and women with lower NGS had an increased cardio-metabolic risk odds ratio (OR) = 1.8, 95% confidence interval (CI) 1.1 to 2.9, p = 0.006, and OR = 1.6, 95% CI 1.0 to 2.5, p = 0.036, respectively). In both sexes, higher levels of all fatness parameters were also associated with increased cardio-metabolic risk (p < 0.001). In both men and women, high FMI had the highest OR for clustered risk (OR = 4.7, 95% CI 2.6 to 8.4, and OR = 7.3, 95% CI 3.4 to 9.7, p < 0.001, respectively). Combined analysis showed that unfitness (lower NGS) and high fat had the highest OR for WC and FMI in men and women, respectively (OR = 5.5, 95% CI 2.6 to 11.4, OR = 7.7, 95% CI 2.3 to 15.8, p < 0.01). Muscular strength and body fatness are independently and jointly associated with increased cardiometabolic risk in young adults, which suggests that both are predictor variables for this.
Open Access
Fatness mediates the influence of muscular fitness on metabolic syndrome in Colombian collegiate students
(Public Library of Science, 2017) García Hermoso, Antonio; Carrillo Arango, Hugo Alejandro; González Ruiz, Katherine; Vivas, Andrés; Triana Reina, Héctor Reynaldo; Martínez Torres, Javier; Prieto Benavides, Daniel Humberto; Correa Bautista, Jorge Enrique; Ramos Sepúlveda, Jeison Alexander; Villa González, Emilio; Peterson, Mark Dean; Ramírez Vélez, Robinson; Ciencias de la Salud; Osasun Zientziak
The purpose of this study was two-fold: to analyze the association between muscular fitness (MF) and clustering of metabolic syndrome (MetS) components, and to determine if fatness parameters mediate the association between MF and MetS clustering in Colombian collegiate students. This cross-sectional study included a total of 886 (51.9% women) healthy collegiate students (21.4 ± 3.3 years old). Standing broad jump and isometric handgrip dynamometry were used as indicators of lower and upper body MF, respectively. Also, a MF score was computed by summing the standardized values of both tests, and used to classify adults as fit or unfit. We also assessed fat mass, body mass index, waist-to-height ratio, and abdominal visceral fat, and categorized individuals as low and high fat using international cut-offs. A MetS cluster score was derived by calculating the sum of the sample-specific zscores from the triglycerides, HDL cholesterol, fasting glucose, waist circumference, and arterial blood pressure. Linear regression models were used to examine whether the association between MF and MetS cluster was mediated by the fatness parameters. Data were collected from 2013 to 2016 and the analysis was done in 2016. Findings revealed that the best profiles (fit + low fat) were associated with lower levels of the MetS clustering (p 0.001 in the four fatness parameters), compared with unfit and fat (unfit + high fat) counterparts. Linear regression models indicated a partial mediating effect for fatness parameters in the association of MF with MetS clustering. Our findings indicate that efforts to improve MF in young adults may decrease MetS risk partially through an indirect effect on improvements to adiposity levels. Thus, weight reduction should be taken into account as a complementary goal to improvements in MF within exercise programs.
Open Access
Handgrip strength and its relationship with white blood cell count in U.S. adolescents
(MDPI, 2021) López Gil, José Francisco; Ramírez Vélez, Robinson; Izquierdo Redín, Mikel; García Hermoso, Antonio; Ciencias de la Salud; Osasun Zientziak; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, ID 420/2019
Background: The role of muscular fitness (as a protecting factor for an optimal immune system) and WBC count remains unclear. To the best of our knowledge, this is the first study to investigate the relationship between the total count of WBC and groups based on handgrip strength and body composition. The aim of this study was to elucidate the relationship between handgrip strength and WBC count in a nationally representative sample of adolescents from the U.S. Methods: We used data from the NHANES cross-sectional study (waves 2011 to 2014). The final analysis included 917 adolescents from 12–17 years old (51.0% boys). Normalized handgrip strength (kg) (NHS) was relativized by body composition parameters (body weight [NHSw], total body fat [NHSf], and trunk fat [NHSt]) assessed with dual energy X-ray absorptiometry. Results: An inverse association was found between total WBC count and all assessments of low NHS in both sexes (p < 0.05). Both boys and girls with low NHS had higher WBC counts in all estimations of NHS than those with high NHS (p < 0.05 for all). All estimations of low NHS showed significant differences with those with intermediate NHS (only in girls) (p < 0.05 for all). Girls with intermediate NHSt exhibited higher WBC count than those with high NHSt (p = 0.004). Conclusions: Our findings suggest that greater levels of NHS are linked to lower total WBC counts. From a public health perspective, our findings are clinically significant and emphasize the relevance of improving muscular fitness during adolescence since it may contribute to boosting the immune system among adolescents.
Open Access
Muscle strength cut-offs for the detection of metabolic syndrome in a nonrepresentative sample of collegiate students from Colombia
(Elsevier, 2018) García Hermoso, Antonio; Tordecilla Sanders, Alejandra; Correa Bautista, Jorge Enrique; Peterson, Mark Dean; Izquierdo Redín, Mikel; Quino Ávila, Aura Cristina; Sandoval Cuellar, Carolina; González Ruiz, Katherine; Ramírez Vélez, Robinson; Ciencias de la Salud; Osasun Zientziak
Background: Evidence shows an association between grip strength and health; however, grip strength cut-offs for the detection of metabolic syndrome (MetS) in Latin American populations are scarce. The purpose of this study was to determine cut-offs of normalized grip strength (NGS) for the detection of MetS in a large nonrepresentative sample of a collegiate student population from Colombia. Methods: A total of 1795 volunteers (61.4% female, age = 20.68 ± 3.10 years, mean ± SD), ranging between 18 and 30 years of age participated in the study. Strength was estimated using a handheld dynamometer and normalized to body mass (handgrip strength (kg)/body mass (kg)). Anthropometrics, serum lipids indices, blood pressure, and fasting plasma glucose were measured. Body composition was measured by bioelectrical impedance analysis. MetS was defined as including ≥3 of the 5 metabolic abnormalities according to the International Diabetes Federation definition. A metabolic risk score was computed from the following components: waist circumference, triglycerides, high-density lipoprotein cholesterol, glucose, and systolic and diastolic blood pressure. Results: Receiver operating curve analysis showed significant discriminatory accuracy of NGS in identifying the thresholds and risk categories. Lower strength was associated with increased prevalence of MetS. In males, weak, intermediate, and strong NGS values at these points were <0.466, 0.466–0.615, >0.615, respectively. In females, these cut-off points were <0.332, 0.332–0.437, >0.437, respectively. Conclusion: Our sex-specific cut-offs of NGS could be incorporated into a clinical setting for identifying college students at cardiometabolic disease risk.