Publication:
Cost-utility analysis of prostatic artery embolization for treatment of lower urinary tract symptoms

dc.contributor.authorCapdevila, Ferran
dc.contributor.authorInsausti, Íñigo
dc.contributor.authorSan Miguel Elcano, Ramón
dc.contributor.authorSánchez Iriso, Eduardo
dc.contributor.authorMontesino San Martín, Manuel
dc.contributor.departmentCiencias de la Saludes_ES
dc.contributor.departmentOsasun Zientziakeu
dc.contributor.departmentEconomíaes_ES
dc.contributor.departmentEkonomiaeu
dc.date.accessioned2023-08-16T14:25:41Z
dc.date.available2024-04-05T23:00:10Z
dc.date.issued2023
dc.date.updated2023-08-16T14:11:53Z
dc.description.abstractPurpose: To perform a post hoc cost–utility analysis of a randomized controlled clinical trial comparing prostatic artery embolization (PAE) and transurethral resection of the prostate (TURP) in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia. Materials and Methods: We conducted a cost–utility analysis over a 5-year period to compare PAE versus TURP from a Spanish National Health System perspective. Data were collected from a randomized clinical trial performed at a single institution. Effectiveness was measured as quality-adjusted life years (QALYs), and an incremental cost-effectiveness ratio (ICER) was derived from the cost and QALY values associated with these treatments. Further sensitivity analysis was performed to account for the impact of reintervention on the cost-effectiveness of both procedures. Results: At the 1-year follow-up, PAE resulted in mean cost per patient of €2904.68 and outcome of 0.975 QALYs per treatment. In comparison, TURP had cost €3846.72 per patient and its outcome was 0.953 QALYs per treatment. At 5 years, the cost for PAE and TURP were €4117.13 and €4297.58, and the mean QALY outcome was 4.572 and 4.487, respectively. Analysis revealed an ICER of €2121.15 saved per QALY gained when comparing PAE to TURP at long-term follow-up. Reintervention rate for PAE and TURP was 12% and 0%, respectively. Conclusions: Compared to TURP, in short term, PAE could be considered a cost-effective strategy within the Spanish healthcare system for patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia. However, in long term, the superiority is less apparent due to higher reintervention rates.en
dc.embargo.lift2024-04-05
dc.embargo.terms2024-04-05
dc.format.mimetypeapplication/pdfen
dc.identifier.citationCapdevila, F., Insausti, I., San Miguel, R., Sanchez-Iriso, E., & Montesino, M. (2023). Cost–utility analysis of prostatic artery embolization for treatment of lower urinary tract symptoms. CardioVascular and Interventional Radiology, 46(8), 1025-1035. https://doi.org/10.1007/s00270-023-03443-9en
dc.identifier.doi10.1007/s00270-023-03443-9
dc.identifier.issn0174-1551
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/45968
dc.language.isoengen
dc.relation.ispartofCardioVascular and Interventional Radiology (2023), 46(8), 1025–1035en
dc.relation.publisherversionhttps://doi.org/10.1007/s00270-023-03443-9
dc.rights© 2023, Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).en
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.subjectBenign prostatic hyperplasiaen
dc.subjectCost-effectivenessen
dc.subjectProstatic artery embolization (PAE)en
dc.subjectTransurethral resection of the prostate (TURP)en
dc.titleCost-utility analysis of prostatic artery embolization for treatment of lower urinary tract symptomsen
dc.typeArtículo / Artikuluaes
dc.typeinfo:eu-repo/semantics/articleen
dc.type.versionVersión aceptada / Onetsi den bertsioaes
dc.type.versioninfo:eu-repo/semantics/acceptedVersionen
dspace.entity.typePublication
relation.isAuthorOfPublicationc358467c-1a3f-4e2c-941c-11af306f1817
relation.isAuthorOfPublication8e25141c-c3ca-481d-98d1-87c85a90d9c6
relation.isAuthorOfPublication5a889cfb-af34-4085-aed8-c77bb154cac1
relation.isAuthorOfPublication.latestForDiscoveryc358467c-1a3f-4e2c-941c-11af306f1817

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