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dc.creatorÁlvarez Álvarez, Ismaeles_ES
dc.creatorNiu, Haoes_ES
dc.creatorGuillén Grima, Franciscoes_ES
dc.creatorAguinaga Ontoso, Inéses_ES
dc.date.accessioned2018-06-17T12:16:39Z
dc.date.available2018-06-17T12:16:39Z
dc.date.issued2016
dc.identifier.issn0301-0546 (Print)
dc.identifier.issn1578-1267 (Electronic)
dc.identifier.urihttps://hdl.handle.net/2454/28894
dc.description.abstractBackground: Wheezing affects children’s quality of life, and is related with asthma in childhood. Although prevalence of wheezing has been previously studied in several countries, there are no reference of worldwide prevalence in infants. The aim of this meta-analysis is to estimate the prevalence of wheezing and recurrent wheezing in infants aged up to two years, and compare the prevalence across world regions. Methods: Literature search was conducted in MEDLINE and SCOPUS databases, looking for observational studies published up to June 2016, including as keywords “prevalence” or “epidemiology” combined with “wheeze”, “wheezing” or “asthma symptoms” and “infant” or “preschool”. Fast*Pro software and random effects Bayesian model were used. Heterogeneity was estimated using I2 statistic, and sensitivity analyses were performed. Results: We identified 109 studies after duplicates were removed. After exclusions, 14 studies were included in the meta-analysis. Prevalence of wheezing and recurrent wheezing were 36.06% (95% CI 35.17-36.96), and 17.41% (95% CI 16.74-18.09), respectively. In European countries, prevalence of wheezing was 30.68% (95% CI 28.97-32.45), and 12.35% (95% CI 11.27-13.47) for recurrent wheezing. Prevalence of wheezing and recurrent wheezing in Latin America were higher, 40.55% (95% CI 39.40-41.71), and 19.27% (95% CI 18.44-20.11), respectively. In Africa, prevalence of wheezing was 15.97% (95% CI 14.05-18.00). Low or no heterogeneity was found in all cases. Conclusions: More than one third of infants suffer from wheezing and almost one fifth from recurrent wheezing, being these illnesses especially prevalent in Latin American countries, pointing out an important public health problem.en
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherElsevieren
dc.relation.ispartofAllergologia et Immunopathologia, Volume 46, Issue 3, May–June 2018, Pages 210-217en
dc.rights© 2016 SEICAP. Published by Elsevier España, S.L.U. The manuscript version is made available under the CC BY-NC-ND 4.0 license.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEpidemiologyen
dc.subjectInfantsen
dc.subjectMeta-analysisen
dc.subjectPrevalenceen
dc.subjectRecurrent wheezingen
dc.subjectWheezingen
dc.titleMeta-analysis of prevalence of wheezing and recurrent wheezing in infantsen
dc.typeArtículo / Artikuluaes
dc.typeinfo:eu-repo/semantics/articleen
dc.contributor.departmentUniversidad Pública de Navarra. Departamento de Ciencias de la Saludes_ES
dc.contributor.departmentNafarroako Unibertsitate Publikoa. Osasun Zientziak Sailaeu
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.identifier.doi10.1016/j.aller.2016.08.011
dc.relation.publisherversionhttps://doi.org/10.1016/j.aller.2016.08.011
dc.type.versionVersión aceptada / Onetsi den bertsioaes
dc.type.versioninfo:eu-repo/semantics/acceptedVersionen


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© 2016 SEICAP. Published by Elsevier España, S.L.U. The manuscript version is made available under the CC BY-NC-ND 4.0 license.
Except where otherwise noted, this item's license is described as © 2016 SEICAP. Published by Elsevier España, S.L.U. The manuscript version is made available under the CC BY-NC-ND 4.0 license.