Díaz Fernández, MarcosAlgarra González, ManuelCalvo Losada, SaturninoQuirante, José JoaquínSarabia, FranciscoPino-González, María Soledad2024-10-032024-10-032024-08-15Díaz-Fernández, M., Algarra, M., Calvo-Losada, S., Quirante, J. J., Sarabia, F., Pino-González, M. S. (2024) Diverse methods with stereoselective induction in the asymmetric Biginelli reaction. Molecules, 29(16), 1-20. https://doi.org/10.3390/molecules291638641420-304910.3390/molecules29163864https://academica-e.unavarra.es/handle/2454/51961The relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric synthetic advances in the formation of dihydropyrimidinones (DHPMs), dihydropyrimidinethiones (DHPMTs), and related compounds. The relevant bibliography on general processes in the Biginelli reaction and some methods of separation of isomers have also been referenced.application/pdfeng© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.PyrimidinesMulticomponent reactionsAsymmetricEnantioselectiveN-heterocyclesBiginelli reactioninfo:eu-repo/semantics/article2024-10-03info:eu-repo/semantics/openAccess