García Hermoso, AntonioEzzatvar, YasminHuerta Uribe, NidiaAlonso Martínez, AliciaChueca-Guindulain, María J.Berrade-Zubiri, SaraIzquierdo Redín, MikelRamírez Vélez, Robinson2022-08-082022-08-082022García-Hermoso, A.; Ezzatvar, Y.; Huerta-Uribe, N.; Alonso-Martínez, A. M.; Chueca-Guindulain, M. J.; Berrade-Zubiri, S.; Izquierdo, M.; Ramírez-Vélez, R. (2022). Effects of exercise training on glycaemic control in youths with type 1 diabetes: a systematic review and meta-analysis of randomised controlled trials. European Journal of Sport Science. 1-121746-139110.1080/17461391.2022.2086489https://academica-e.unavarra.es/handle/2454/43706The aim of the study is to evaluate whether exercise interventions are associated with improved glycaemic control in children and adolescents with type 1 diabetes mellitus (T1DM), and to examine its relationship with the characteristics of the intervention (i.e. type, intensity, length, and duration of the sessions). Eligible criteria were randomised controlled trials of youth aged 6– 18 years with T1DM, participating in an exercise-based intervention where glycaemic control is measured (i.e. glycated haemoglobin [HbA1c]). Pooled effect sizes (Hedges’g) were calculated using random-effects inverse-variance analyses. Fourteen studies enrolling 509 patients were analysed. Effect size was expressed as Hedges’ g to correct for possible small sample bias. Overall, HbA1c levels in the exercise group (g = –0.38 95% confidence interval [CI], –0.66 to –0.11; mean difference [MD] = –0.62%) were reduced compared with the control group. Concurrent training (g = –0.63 95%CI, –1.05 to –0.21), high-intensity exercise (g = –0.43 95%CI, –0.83 to –0.03), interventions ≥24 weeks (g = –0.92 95%CI, –1.44 to –0.40), and sessions ≥60 minutes (g = –0.71 95%CI, –1.05 to –0.08) showed larger changes (MD = –0.66% to 1.30%). In conclusion, our study suggests that programmes longer than 24 weeks with at least 60 min/session of high-intensity concurrent exercise may serve as a supportive therapy to metabolic control in youth with T1DM.application/pdfeng© 2022 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.Type 1 diabetes mellitusGlycaemic controlExerciseAerobicResistanceinfo:eu-repo/semantics/article2022-08-08info:eu-repo/semantics/openAccess