Pimenta, Adriano MarçalDeus Mendonça, Raquel deLahortiga Ramos, FranciscaFernández-Lázaro, CésarMartínez González, Miguel ÁngelSánchez Villegas, María Almudena2022-08-022022-08-022022Pimenta, A. M.; De-Deus-Mendonça, R.; Lahortiga-Ramos, F.; Fernandez-Lazaro, C. I.; Martínez-González, M. A.; Sánchez-Villegas, A. (2022). Sedentary behaviors and risk of depression in the Seguimiento Universidad de Navarra cohort: the SUN Project. Cadernos de Saude Publica. 38,20102-311X10.1590/0102-311X00076621https://academica-e.unavarra.es/handle/2454/43655The study aimed to prospectively examine the association between different sedentary behaviors and the risk of depression. We included 12,691 Spanish university graduates (mean age: 36.7 year; SD: 11.5), participants of the Seguimiento Universidad de Navarra cohort (the SUN Project), initially free of depression who were followed-up for a median of 10.9 years. Based on items presented in our baseline questionnaire, time spent in four sedentary behaviors (hours/day) were evaluated: overall sitting time; TV-viewing; computer use; and driving. Participants were classified as incident cases of depression if they reported a physician diagnosis of depression in at least one of the follow-up assessments conducted after the first two years of follow-up. Cox regression models were used to assess the relationship between sedentary behaviors and depression. A total of 560 incident cases of depression were identified during follow-up. We found no significant association between overall sitting time, TV-viewing or driving and risk of depression. On the other hand, computer use was directly associated with the risk of developing depression during the follow-up (p-value for trend = 0.020), with the participants in the highest quartile of computer use (3.64 to 10 hours/week) having a higher risk of developing depression (HR = 1.33; 95%CI: 1.05-1.70) than those in the lowest quartile (0 to 0.25 hours/week) after adjusting for potential confounders. Prolonged use of computer was independently associated with an increased risk of developing depression among young middle-aged adult university graduates from a Spanish cohort.application/pdfengThis article is published in Open Access under the Creative Commons Attribution licenseAdultCohort studiesComputersDepressionSedentary behaviorinfo:eu-repo/semantics/article2022-07-20info:eu-repo/semantics/openAccess