Rapún Araiz, BeatrizHaag, Andreas F.Solano Goñi, CristinaLasa Uzcudun, Íñigo2021-01-202021-01-2020201369-5274 (Electronic)10.1016/j.mib.2020.02.004https://academica-e.unavarra.es/handle/2454/39034Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. Differences in the content of two-component systems are related with the capacity of the bacteria to colonize different niches or improve the efficiency to grow under the conditions of the existing niche. This review highlights differences in the TCS content between Staphylococcus aureus and Staphylococcus saprophyticus as a case study to exemplify how the ability to sense and respond to the environment is relevant for bacterial capacity to colonize and survive in/on different body surfaces.8 p.application/pdfeng© 2020 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.Staphylococcus aureusStaphylococcus saprophyticusBacteriasinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessAcceso abierto / Sarbide irekia