Campano, Teresa E.Iriarte, IgorOlaizola, OlatzEtxabe, JulenMielgo, AntoniaGanboa, IñakiOdriozola Ibarguren, José ManuelGarcía Castillo, Jesús MaríaOiarbide, MikelPalomo, Claudio2019-12-202020-01-1620190947-653910.1002/chem.201805542https://academica-e.unavarra.es/handle/2454/35938Various sets of enolizable alkynyl ketones (including methyl ynones with α-aryl, α-alkenyl, and α-alkoxy groups) were able to react smoothly with nitroolefins with the assistance of bifunctional Brønsted base/H-bond catalysts to provide adducts with two consecutive tertiary stereocenters in a highly diastereo- and enantioselective fashion. Further transformation of the obtained adducts into optically active acyclic and polycyclic molecules, including some with intricate carbon skeletons, was also demonstrated.9 p.application/pdfeng© 2019 Wiley-VCH Verlag GmbH &Co. KGaA, WeinheimAlkynyl ketonesAsymmetric catalysisBrønsted basesMichael reactionOrganocatalysisEnantioselective addition of alkynyl ketones to nitroolefins assisted by Brønsted base/H-bonding catalysisinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccess