Listar por autor UPNA "Sánchez Ruiz de Gordoa, Javier"
Mostrando ítems 1-5 de 5
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Association of blood-based DNA methylation markers with late-onset alzheimer disease: a potential diagnostic approach
Background and Objectives: There is an urgent need to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent advances in blood-based measurements of phosphorylated tau (pTau) species are promising ... -
Gender-dependent deregulation of linear and circular RNA variants of homer1 in the entorhinal cortex of Alzheimer’s disease
The HOMER1 gene is involved in synaptic plasticity, learning and memory. Recent studies show that circular RNA derived from HOMER1 (circHOMER1) expression is altered in some Alzheimer’s disease (AD) brain regions. In ... -
Is the phenotype designation by PSP-MDS criteria stable throughout the disease course and consistent with tau distribution?
Introduction: the MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do not discriminate the phenotype diversity. Our purpose was to search for anatomopathological differences among PSP phenotypes ... -
Parálisis supranuclear progresiva: correlación clínico-patológica y aproximación al papel patogénico de lamicroglía
La parálisis supranuclear progresiva (PSP) es una enfermedad neurodegenerativa que se manifiesta clínicamente como un parkinsonismo atípico y su base patológica son los depósitos de proteína tau en neuronas y células ... -
Twofold binary image consensus for medical imaging meta-analysis
In the field of medical imaging, ground truth is often gathered from groups of experts, whose outputs are generally heterogeneous. This procedure raises questions on how to compare the results obtained by automatic algorithms ...