Listar por autor UPNA "Encío Martínez, Ignacio"
Mostrando ítems 21-32 de 32
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A novel prognostic biomarker panel for early‐stage colon carcinoma
Azcue Sanromán, Pablo; Guerrero Setas, David; Encío Martínez, Ignacio
; Ibáñez Beroiz, B. ; Mercado Gutiérrez, María R.; Vera García, Ruth; Gómez Dorronsoro, María Luisa (MDPI, 2021)
Artículo / Artikulua 
Molecular characterization of colorectal cancer has helped us understand better the biology of the disease. However, previous efforts have yet to provide significant clinical value in order to be integrated into clinical ... -
Novel selenadiazole derivatives as selective antitumor and radical scavenging agents
Ruberte, Ana Carolina; Plano, Daniel; Encío Martínez, Ignacio ; Aydillo, Carlos; Sharma, Arun K.; Sanmartín, Carmen (Elsevier, 2018)
Artículo / Artikulua
Twenty-seven novel benzo[c][1,2,5]selenadiazole-5-carboxylic acid (BSCA) derivatives were designed and synthesized. Anti-proliferative activity of these structures was tested in vitro against a panel of five human cancer ... -
Organoseleno cytostatic derivatives: autophagic cell death with AMPK and JNK activation
Garnica, Pablo; Encío Martínez, Ignacio ; Plano, Daniel; Palop, Juan Antonio; Sanmartín, Carmen (Elsevier Masson SAS, 2019)
Artículo / Artikulua
Selenocyanates and diselenides are potential antitumor agents. Here we report two series of selenium derivatives related to selenocyanates and diselenides containing carboxylic, amide and imide moieties. These compounds ... -
PD-L1 as a prognostic factor in early-stage colon carcinoma within the immunohistochemical molecular subtype classification
Azcue Sanromán, Pablo; Encío Martínez, Ignacio ; Guerrero Setas, David; Suárez Alecha, Javier; Galbete Jiménez, Arkaitz ; Mercado Gutiérrez, María R.; Vera García, Ruth; Gómez Dorronsoro, María Luisa (MDPI, 2021)
Artículo / Artikulua
Colorectal cancer (CRC) is a very heterogeneous disease. Efforts to characterize and search for biomarkers for these patients are currently ongoing in the hope of establishing a more targeted therapeutic approach. The role ... -
Pediococcus acidilactici pA1c® improves the beneficial effects of metformin treatment in type 2 diabetes by controlling glycaemia and modulating intestinal microbiota
Cabello Olmo, Miriam ; Oneca, María ; Urtasun Alonso, Raquel ; Pajares Villandiego, María Josefa ; Goñi Irigoyen, Saioa ; Riezu Boj, José I.; Milagro, F. I. ; Ayo, Josune; Encío Martínez, Ignacio ; Barajas Vélez, Miguel Ángel ; Araña Ciordia, Miriam (MDPI, 2023)
Artículo / Artikulua
Type 2 diabetes (T2D) is a complex metabolic disease, which involves maintained hyperglycemia, mainly due to the development of an insulin resistance process. Metformin administration is the most prescribed treatment for ... -
Role of postbiotics in diabetes mellitus: current knowledge and future perspectives
Cabello Olmo, Miriam ; Araña Ciordia, Miriam ; Urtasun Alonso, Raquel ; Encío Martínez, Ignacio ; Barajas Vélez, Miguel Ángel (MDPI, 2021)
Artículo / Artikulua
In the last decade, the gastrointestinal microbiota has been recognised as being essential for health. Indeed, several publications have documented the suitability of probiotics, prebiotics, and symbiotics in the management ... -
Seleno-analogs of scaffolds resembling natural products a novel warhead toward dual compounds
Astráin-Redín, Nora; Talavera, Irene; Moreno, Esther; Ramírez, María J.; Martínez-Sáez, Nuria; Encío Martínez, Ignacio ; Sharma, Arun K.; Sanmartín, Carmen; Plano, Daniel (MDPI, 2023)
Artículo / Artikulua
Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated ... -
Synthesis and pharmacological screening of several aroyl and heteroaroyl selenylacetic acid derivatives as cytotoxic and antiproliferative agents
Sanmartín, Carmen; Plano, Daniel; Domínguez, Enrique; Font, María; Calvo, Alfonso; Prior, Celia; Encío Martínez, Ignacio ; Palop, Juan Antonio (MDPI, 2009)
Artículo / Artikulua
The synthesis and cytotoxic activity of a series of twenty six aroyl and heteroaroyl selenylacetic acid derivatives of general formula Ar-CO-Se-CH(2)-COOH or Heterar-CO-Se-CH(2)-COOH are reported. The synthesis was carried ... -
Targeting key players of neuroendocrine differentiation in prostate cancer
Zamora Álvarez, Irene; Freeman, Michael R.; Encío Martínez, Ignacio ; Rotinen Díaz, Mirja Sofia (MDPI, 2023)
Artículo / Artikulua
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer (PC) that commonly emerges through a transdifferentiation process from prostate adenocarcinoma and evades conventional therapies. ... -
Thermal characterization, polymorphism, and stability evaluation of Se-NSAID derivatives with potent anticancer activity
Ramos Inza, Sandra; Almagro, Eneko; Font, María; Encío Martínez, Ignacio ; Plano, Daniel; Sanmartín, Carmen; Sirera, Rafael; Lizarraga, Elena (Springer, 2024)
Artículo / Artikulua
Stability, thermal characterization, and identification of possible polymorphism are relevant in the development of novel therapeutic drugs. In this context, thirty new nonsteroidal anti-inflammatory drug (NSAID) derivatives ... -
Transcriptional regulation of type 11 17β-hydroxysteroid dehydrogenase expression in prostate cancer cells
Rotinen Díaz, Mirja Sofia ; Villar Bécares, Joaquín ; Celay Leoz, Ion ; Serrano Mendioroz, Irantzu ; Notario, Vicente; Encío Martínez, Ignacio (Elsevier, 2011)
Artículo / Artikulua
Type 11 Hydroxysteroid (17-beta) dehydrogenase (HSD17B11) catalyzes the conversion of 5α-androstan-3α,17β-diol into androsterone suggesting that it may play an important role in androgen metabolism. We previously described ... -
Unveiling a new selenocyanate as a multitarget candidate with anticancer, antileishmanial and antibacterial potential
Ramos Inza, Sandra; Henriquez-Figuereo, Andreina; Moreno, Esther; Berzosa, Melibea; Encío Martínez, Ignacio ; Plano, Daniel; Sanmartín, Carmen (MDPI, 2022)
Artículo / Artikulua
Currently, cancer, leishmaniasis and bacterial infections represent a serious public health burden worldwide. Six cinnamyl and benzodioxyl derivatives incorporating selenium (Se) as selenocyanate, diselenide, or selenide ...
