Listar por autor UPNA "García Martínez, Begoña"
Mostrando ítems 1-13 de 13
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Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection
Gil Puig, Carmen
; Solano Goñi, Cristina ; Burgui Erice, Saioa ; Latasa Osta, Cristina ; García Martínez, Begoña ; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo ; Valle Turrillas, Jaione (American Society for Microbiology, 2014)
Artículo / Artikulua 
The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ... -
Biofilm switch and immune response determinants at early stages of infection
Valle Turrillas, Jaione ; Solano Goñi, Cristina ; García Martínez, Begoña ; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo (Elsevier (Cell Press), 2013)
Artículo / Artikulua
Biofilm development is recognized as a major virulence factor underlying most chronic bacterial infections. When a biofilm community is established, planktonic cells growing in the surroundings of a tissue switch to a ... -
Coordinated cyclic-di-GMP repression of salmonella motility through YcgR and cellulose
Zorraquino Salvo, Violeta; García Martínez, Begoña ; Latasa Osta, Cristina ; Echeverz Sarasúa, Maite ; Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Lasa Uzcudun, Íñigo ; Solano Goñi, Cristina (American Society for Microbiology, 2013)
Artículo / Artikulua
Cyclic di-GMP (c-di-GMP) is a secondary messenger that controls a variety of cellular processes, including the switch between a biofilm and a planktonic bacterial lifestyle. This nucleotide binds to cellular effectors in ... -
A DIVA vaccine strain lacking RpoS and the secondary messenger c-di-GMP for protection against salmonellosis in pigs
Gil Puig, Carmen ; Latasa Osta, Cristina ; García Ona, Enrique ; Lázaro, Isidro; Labairu, Javier; Echeverz Sarasúa, Maite ; Burgui Erice, Saioa ; García Martínez, Begoña ; Lasa Uzcudun, Íñigo ; Solano Goñi, Cristina (BioMed Central, 2020)
Artículo / Artikulua
Salmonellosis is the second most common food-borne zoonosis in the European Union, with pigs being a major reservoir of this pathogen. Salmonella control in pig production requires multiple measures amongst which vaccination ... -
Evaluation of a Salmonella strain lacking the secondary messenger c-di-GMP and RpoS as a live oral vaccine
Latasa Osta, Cristina; Echeverz Sarasúa, Maite ; García Ona, Enrique ; Burgui Erice, Saioa ; Casares, Noelia; Hervás Stubbs, Sandra ; Lasarte, Juan José; Lasa Uzcudun, Íñigo ; Solano Goñi, Cristina ; García Martínez, Begoña ; Gil Puig, Carmen (Public Library of Science, 2016)
Artículo / Artikulua
Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through the consumption of contaminated food, with chicken and pig related products being key reservoirs of infection. Although numerous ... -
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
San Román Aberasturi, Beatriz ; Lasa Uzcudun, Íñigo ; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz ; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria ; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña ; Andrés, Ximena de; Zabaleta, Virginia ; Mansilla, Cristina; Farrán Blanch, Inmaculada (BioMed Central, 2012)
Artículo / Artikulua
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ... -
Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella
Solano Goñi, Cristina ; García Martínez, Begoña ; Latasa Osta, Cristina ; Toledo Arana, Alejandro ; Zorraquino Salvo, Violeta; Valle Turrillas, Jaione ; Casals, Joan; Pedroso, Enrique; Lasa Uzcudun, Íñigo (National Academy of Sciences, 2009)
Artículo / Artikulua
Bacteria have developed an exclusive signal transduction system involving multiple diguanylate cyclase and phosphodiesterase domain-containing proteins (GGDEF and EAL/HD-GYP, respectively) that modulate the levels of the ... -
Lack of the PGA exopolysaccharide in Salmonella as an adaptive trait for survival in the host
Echeverz Sarasúa, Maite ; García Martínez, Begoña ; Sabalza Baztán, Amaia ; Valle Turrillas, Jaione ; Gabaldón Estevan, Juan Antonio; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo (Public Library of Science, 2017)
Artículo / Artikulua
Many bacteria build biofilm matrices using a conserved exopolysaccharide named PGA or PNAG (poly-β-1,6-N-acetyl-D-glucosamine). Interestingly, while E. coli and other members of the family Enterobacteriaceae encode the ... -
El ozono no consigue la desinfección de los vehículos de emergencias de virus similares al SARS-CoV-2
Biurrun Cía, Jorge; García Martínez, Begoña ; Pérez Montero, Andrea; Kochan, Grazyna; Escors Murugarren, David; Crespo Martínez, José; Lasa Uzcudun, Íñigo; Echarri Sucunza, Alfredo (SEMES, 2020)
Artículo / Artikulua
Ante la pandemia generada por el coronavirus SARS-CoV-2, la desinfección de los vehículos de emergencias supone una cuestión crucial. No en vano, son medio de transporte de pacientes contagiados y podrían ser vector de ... -
The regulon of the RNA chaperone CspA and its auto-regulation in Staphylococcus aureus
Caballero Sánchez, Carlos; Menéndez Gil, Pilar; Catalán Moreno, Arancha; Vergara Irigaray, Marta ; García Martínez, Begoña ; Segura, Víctor; Irurzun Domínguez, Naiara; Villanueva San Martín, Maite ; Ruiz de los Mozos Aliaga, Igor ; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro (Oxford University Press, 2018)
Artículo / Artikulua
RNA-binding proteins (RBPs) are essential to finetune gene expression. RBPs containing the coldshock domain are RNA chaperones that have been extensively studied. However, the RNA targets and specific functions for ... -
Relevant role of fibronectin-binding proteins in Staphylococcus aureus biofilm-associated foreign-body infections
Vergara Irigaray, Marta; Valle Turrillas, Jaione ; Merino, Nekane ; Latasa Osta, Cristina ; García Martínez, Begoña ; Ruiz de los Mozos Aliaga, Igor ; Solano Goñi, Cristina ; Toledo Arana, Alejandro ; Penadés, José R.; Lasa Uzcudun, Íñigo (American Society for Microbiology, 2009)
Artículo / Artikulua
Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains ... -
Salmonella biofilm development depends on the phosphorylation status of RcsB
Latasa Osta, Cristina; García Martínez, Begoña ; Echeverz Sarasúa, Maite ; Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo (American Society for Microbiology, 2012)
Artículo / Artikulua
The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ... -
Sensory deprivation in Staphylococcus aureus
Villanueva San Martín, Maite ; García Martínez, Begoña ; Valle Turrillas, Jaione ; Rapún Araiz, Beatriz ; Ruiz de los Mozos Aliaga, Igor ; Solano Goñi, Cristina ; Martí, Miguel; Penadés, José R.; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo (Springer Nature, 2018)
Artículo / Artikulua
Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ...
