Now showing items 41-48 of 48

    • Sensory deprivation in Staphylococcus aureus 

      Villanueva San Martín, Maite Upna; García Martínez, Begoña Upna; Valle Turrillas, Jaione Upna; Rapún Araiz, Beatriz; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna; Martí, Miguel; Penadés, José R.; Toledo Arana, Alejandro Upna; Lasa Uzcudun, Íñigo Upna (Springer Nature, 2018)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ...
    • Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals 

      Taglialegna, Agustina Upna; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Matthews, Steve; Penadés, José R.; Lasa Uzcudun, Íñigo Upna; Valle Turrillas, Jaione Upna (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
      Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
    • Staphylococcus aureus develops an alternative, ica-independent biofilm in the absence of the arlRS two-component system 

      Toledo Arana, Alejandro Upna; Merino, Nekane; Vergara Irigaray, Marta Upna; Débarbouillé, Michel; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      The biofilm formation capacity of Staphylococcus aureus clinical isolates is considered an important virulence factor for the establishment of chronic infections. Environmental conditions affect the biofilm formation capacity ...
    • Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins 

      Tormo Más, María Ángeles; Ferrer, María Desamparados; Maiques, Elisa; Ubeda, Carles; Selva, Laura; Lasa Uzcudun, Íñigo Upna; Calvete, Juan J.; Novick, Richard P.; Penadés, José R. (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus pathogenicity islands (SaPIs) have an intimate relationship with temperate staphylococcal phages. During phage growth, SaPIs are induced to replicate and are efficiently encapsidated into special small ...
    • Study of the molecular mechanisms underlying Bap-mediated cell-cell interactions in Staphylococcus aureus 

      Taglialegna, Agustina Upna (2016)   Tesis doctoral / Doktoretza tesia  OpenAccess
      La mayoría de los microorganismos son capaces de vivir en comunidades sésiles, siendo esta forma de crecimiento bastante más frecuente que la forma de vida planctónica. En estas comunidades microbianas, conocidas como ...
    • A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria 

      Quiles Puchalt, Nuria; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Toledo Arana, Alejandro Upna; Monedero, Vicente; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2013)   Artículo / Artikulua  OpenAccess
      The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families ...
    • Towards the identification of the common features of bacterial biofilm development 

      Lasa Uzcudun, Íñigo Upna (Sociedad Española de Microbiología, 2006)   Artículo / Artikulua  OpenAccess
      Los microorganismos pueden vivir y proliferar como células individuales que nadan libremente en el medio o crecer en comunidades multicelulares muy bien organizadas dentro de una matriz que ellas mismas han sintetizado y ...
    • Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray 

      Segura, Víctor; Toledo Arana, Alejandro Upna; Uzqueda, Maite; Lasa Uzcudun, Íñigo Upna; Muñoz Barrutia, Arrate (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: High-density oligonucleotide microarray is an appropriate technology for genomic analysis, and is particulary useful in the generation of transcriptional maps, ChIP-on-chip studies and re-sequencing of the ...